Paula S. Haddad

ORCID: 0000-0001-5362-1861
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About
Contact & Profiles
Research Areas
  • Nanoparticle-Based Drug Delivery
  • Iron oxide chemistry and applications
  • Characterization and Applications of Magnetic Nanoparticles
  • Nanoparticles: synthesis and applications
  • Inorganic and Organometallic Chemistry
  • Magnetic Properties and Synthesis of Ferrites
  • Nanoplatforms for cancer theranostics
  • Catalytic Processes in Materials Science
  • Transition Metal Oxide Nanomaterials
  • Organometallic Complex Synthesis and Catalysis
  • Lipid Membrane Structure and Behavior
  • Gold and Silver Nanoparticles Synthesis and Applications
  • X-ray Diffraction in Crystallography
  • Nanomaterials for catalytic reactions
  • Multicomponent Synthesis of Heterocycles
  • Advanced Nanomaterials in Catalysis
  • Nitric Oxide and Endothelin Effects
  • Crystal structures of chemical compounds
  • Crystallization and Solubility Studies
  • Graphene and Nanomaterials Applications
  • Metal complexes synthesis and properties
  • Photodynamic Therapy Research Studies
  • Advanced Drug Delivery Systems
  • Gas Sensing Nanomaterials and Sensors
  • Nanocluster Synthesis and Applications

Universidade Federal de São Paulo
2014-2024

Fundação de Apoio à Universidade Federal de São Paulo
2017

Diversité, adaptation et développement des plantes
2017

Universidade de São Paulo
2004-2012

Brazilian Synchrotron Light Laboratory
2007-2010

Universidade Estadual do Paraná
2009

Universidade Estadual de Campinas (UNICAMP)
2009

Centre National de la Recherche Scientifique
2006

Institut Charles Sadron
2006

Centro Universitário de Araraquara
2003-2004

The present study is focused on the synthesis and characterization of nitric oxide (NO)-releasing superparamagnetic iron nanoparticles, their incorporation in Pluronic F127 hydrogel with great potential for topical applications.

10.1039/c6ra28633j article EN cc-by-nc RSC Advances 2017-01-01

Iron oxide magnetic nanoparticles have been proposed for an increasing number of biomedical applications, such as drug delivery. To this end, toxicological studies their potent effects in biological media must be better evaluated. The aim study was to synthesize, characterize, and examine the potential vitro cytotoxicity genotoxicity thiolated (SH) S-nitrosated (S-NO) iron superparamagnetic toward healthy cancer cell lines. Fe3O4 were synthesized by coprecipitation techniques coated with...

10.1021/tx500113u article EN publisher-specific-oa Chemical Research in Toxicology 2014-06-20

We study the photodecomposition of phospholipid bilayers in aqueous solutions methylene blue. Observation giant unilamellar vesicles under an optical microscope reveals a consistent pattern membrane disruption as function blue concentration and photon density for different substrates supporting vesicles.

10.1021/la061510v article EN Langmuir 2006-12-15

The presence of textile dyes in the environment is a concern since they can be composed organic and inorganic recalcitrant and/or toxic compounds.Ferromagnetic nanocomposites prepared from agroindustry residues, cork powder (CP), yeast biomass (YB) were synthetized, characterized, applied for adsorption.The CP, YB, ferromagnetic nanoparticles (MNP), powdered (CP-MNP), ethanol industry (YB-MNP) evaluated as sorbents methylene blue.All also to cleanup dyed cotton fabric effluent, containing...

10.5004/dwt.2018.21914 article EN cc-by-nc-nd Desalination and Water Treatment 2018-04-01

Iron oxide magnetic nanoparticles have been employed as potential vehicles for a large number of biomedical applications, such drug delivery. This article describes the synthesis, characterization and in vitro cytotoxic COVID-19 cells evaluation DMSA superparamagnetic iron nanoparticles. Magnetite (Fe3O4) were synthesized by co-precipitation salts coated with meso-2,3-dimercaptosuccinic acid (DMSA) molecule. Structural morphological characterizations performed X-ray diffraction (XRD),...

10.1002/slct.202101900 article EN ChemistrySelect 2021-08-17

This work reports the synthesis and toxicological evaluation of surface modified magnetic iron oxide nanoparticles as vehicles to carry deliver nitric (NO). The (MNPs) was coated with two thiol-containing hydrophilic ligands: mercaptosuccinic acid (MSA) or dimercaptosuccinic (DMSA), leading thiolated MNPs. Free thiols groups on MSA- DMSA-MNPs were nitrosated NO-releasing genotoxicity thiolated-coated MNPs evaluated towards human lymphocyte cells by comet assay. No observed due exposure...

10.1088/1742-6596/429/1/012021 article EN Journal of Physics Conference Series 2013-04-10

Nitric oxide (NO) is involved in several physiological and pathophysiological processes, such as control of vascular tone immune responses against microbes. Thus, there great interest the development NO-releasing materials to carry deliver NO for biomedical applications. Magnetic iron nanoparticles have been used important pharmacological applications, including drug-delivery. In this work, magnetic were coated with thiol-containing hydrophilic ligands: mercaptosuccinic acid (MSA)...

10.1088/1742-6596/429/1/012034 article EN Journal of Physics Conference Series 2013-04-10

Superparamagnetic iron oxide nanoparticles (SPIONs), with appropriate surface coating, are commonly used for biomedical applications such as photodynamic therapy (PDT). This work describes the preparation and characterization of methylene blue (MB)-containing silica-coated SPIONs. Upon exposure to light, MB reacts molecular oxygen generates singlet (1O2) which is cytotoxic causes irreversible damage tumor tissues. In this work, SPIONs were synthesized by co-precipitation coated a...

10.1166/jnn.2017.12715 article EN Journal of Nanoscience and Nanotechnology 2017-01-01

This work is an innovative study of ordered mesoporous silica (SBA-15) nanocomposites, with different morphologies, and superparamagnetic iron oxide nanoparticles (SPIONs), as promising drug delivery vehicles guided by magnetization. Incorporating SPIONs into SBA-15 great interest because it can improve controlled drugs well avoid agglomeration the nanoparticles. were prepared coprecipitation thermal decomposition methods incorporated SBA-15, incipient wetness impregnation method. The...

10.1021/acsanm.1c02861 article EN ACS Applied Nano Materials 2021-12-06
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