A5036048949- Electrospun Nanofibers in Biomedical Applications
- Muon and positron interactions and applications
- biodegradable polymer synthesis and properties
- Electrohydrodynamics and Fluid Dynamics
- Advanced Drug Delivery Systems
- Drug Solubulity and Delivery Systems
- 3D Printing in Biomedical Research
- Advanced Cellulose Research Studies
- Membrane Separation and Gas Transport
- Graphene and Nanomaterials Applications
- Synthesis and characterization of novel inorganic/organometallic compounds
- Wound Healing and Treatments
- Advanced Sensor and Energy Harvesting Materials
- Bee Products Chemical Analysis
- Antimicrobial agents and applications
- Chemical Reactions and Isotopes
- Dermatology and Skin Diseases
- Autophagy in Disease and Therapy
- Fluid Dynamics Simulations and Interactions
- Microencapsulation and Drying Processes
- Coordination Chemistry and Organometallics
- Engineering Applied Research
- Fire effects on concrete materials
- Pharmacological Receptor Mechanisms and Effects
- Antimicrobial Peptides and Activities
Semmelweis University
2014-2024
Egis Pharmaceuticals (Hungary)
2024
Eötvös Loránd University
2013
Gedeon Richter (Hungary)
2012
Drug repositioning is a high-priority and feasible strategy in the field of oncology research, where unmet medical needs are continuously unbalanced. Disulfiram potential non-chemotherapeutic, adjuvant anticancer agent. However, clinical translation limited by drug's poor bioavailability. Therefore, molecular encapsulation disulfiram with cyclodextrins evaluated to enhance solubility stability drug. The present work describes for first time complexation randomly methylated-β-cyclodextrin. A...
The application of high-speed rotary spinning can offer a useful mean for either preparation fibrous intermediate conventional dosage forms or drug delivery systems. Polyvinylpyrrolidone (PVP) and poly(vinylpyrrolidone-vinylacetate) (PVP VA) micro- nanofibers different polymer concentrations solvent ratios were prepared with technique. In order to study the influence parameters that enable successful fiber production from polymeric viscous solutions, complex macrostructural screening method...
The vertical diffusion cell is an in vitro laboratory device for the study of drug release and permeation semi-solid topical formulations patches. Both static dynamic versions are used practice, operation which can be automated. available at a reasonable cost smaller, mainly transdermal patches, amount sampling fluid replenished same time as sample, sampled without automation system, simultaneous replenishment acceptor by hydrostatic pressure helps keeping chamber bubble-free.
During the last decade, formulation of nanofibrous materials loaded with different drugs for biomedical applications has evoked considerable interest. The large specific surface area, special micro- and macrostructure fiber mats, possibility gradual release site-specific local delivery active compounds lead to cytotoxicity decrease enhancement therapeutic effect implants. present review details spinning techniques applied design drug systems. It furthermore deals use various polymers that...
In our current research, sucrose palmitate (SP) was applied as a possible permeation enhancer for buccal use. This route of administration is novelty there no literature on the use SP in mucoadhesive films. Films containing were prepared at different temperatures, with concentrations and lengths hydroxypropyl methylcellulose (HPMC) chains. The mechanical, structural, vitro properties films investigated. Tensile strength force measured device software developed Institute. Positron...
Fiber-based dosage forms are potential alternatives of conventional from the point improved extent and rate drug dissolution. Rotary-spun polymer fibers cast films were prepared micronized in order to direct compress after homogenization with tabletting excipients. Particle size distribution powder mixtures homogenized excipients determined by laser scattering particle analyzer. Powder rheological behavior containing was also compared. Positron annihilation lifetime spectroscopy applied for...