A5027254983- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Crystallization and Solubility Studies
- Protein purification and stability
- Bone Tissue Engineering Materials
- Analytical Chemistry and Chromatography
- Analytical Methods in Pharmaceuticals
- Pharmaceutical studies and practices
- Nanoparticles: synthesis and applications
- Ocular Surface and Contact Lens
- Spectroscopy and Chemometric Analyses
- Microencapsulation and Drying Processes
- Muon and positron interactions and applications
- Hydrogels: synthesis, properties, applications
- Pharmacological Effects of Natural Compounds
- Granular flow and fluidized beds
- Graphene and Nanomaterials Applications
- Thermal and Kinetic Analysis
- Drug-Induced Hepatotoxicity and Protection
- Pharmaceutical Quality and Counterfeiting
- biodegradable polymer synthesis and properties
- Pregnancy and Medication Impact
- Mineral Processing and Grinding
- Proteins in Food Systems
- Synthesis and properties of polymers
University of Szeged
2016-2025
University of Novi Sad
2022
Országos Gyógyintézeti Központ
1990
Currently, pharmaceutical companies are working on innovative methods, processes and products. Oral mucoadhesive systems, such as tablets, gels, polymer films, among these possible systems possess many advantages, including the possibility to be applied in swallowing problems. The present study focused formulating buccal films investigating physical physical–chemical properties of films. Sodium alginate (SA) hydroxypropyl methylcellulose (HPMC) were used film-forming agents, glycerol (GLY)...
Recently, titanate nanotubes (TNTs) have been receiving more attention and becoming an attractive candidate for use in several disciplines. With their promising results outstanding performance, they bring added value to any field using them, such as green chemistry, engineering, medicine. Their good biocompatibility, high resistance, special physicochemical properties also provide a wide spectrum of advantages that could be crucial importance investment different platforms, especially...
Vaginal drug delivery systems can provide a long-term and constant liberation of the active pharmaceutical ingredient even for months. For our experiment, FDM 3D printing was used to manufacture vaginal ring samples from thermoplastic polyurethane filament, which enables fast manufacturing complex, personalized medications. be an excellent alternative instead industrial manufacturing, is complicated time-consuming. In work, printed rings were filled manually with jellified metronidazole or...
Background: Nanotechnology has been the main area of focus for research in different disciplines, such as medicine, engineering, and applied sciences. Therefore, enormous efforts have made to insert use nanoparticles into daily routines platforms due their impressive performance huge potential they could offer. Among numerous types nanomaterials, titanate nanotubes widely recognised some most promising nanocarriers outstanding profile brilliant design. Their implementation pharmaceutical...
Background: Captopril (CAP), an angiotensin-converting enzyme inhibitor (ACEI), is widely prescribed for managing hypertension, heart failure, and related conditions. When administered orally, CAP undergoes hepatic metabolism, resulting in a bioavailability of 60–75%. However, to bypass the first-pass metabolism other limitations oral route, mucoadhesive buccal films have gained attention as promising alternative with several advantages. The aim this work was formulation optimization...
For many years, researchers have been making efforts to find a manufacturing technique, as well drug delivery system, that will allow for oral of biopharmaceuticals their target site action without impairing biological activity. Due the positive in vivo outcomes this formulation strategy, self-emulsifying systems (SEDDSs) intensively studied last few years way overcoming different challenges associated with macromolecules. The purpose present study was examine possibility developing solid...
Sorbic acid and its potassium calcium salts used as food preservatives sorbic chloride were submitted to thermal analysis in order characterize their behavior on heating cooling processes, using TG/DTG/DTA, TG-MS, DSC, hot stage microscopy DRX analysis. melted decomposed under dynamic heating. Under isothermal it sublimated without decomposition before melting (T < 134 °C). The salt presented a solid-solid phase transition decomposition. Both temperatures higher than the melting, producing...
Buccal drug administration is a less explored area, therefore researchers and companies focus on its research because of innovative potential opportunities. polymer films (patches) are considered to be an form have great number advantageous properties. Firstly, patients who suffer from swallowing problems children can also apply them. The active pharmaceutical ingredient enters the systemic circulation directly without degradation transformation. aim this study was formulate buccal with...
Nowadays, the buccal administration of mucoadhesive films is very promising. Our aim was to prepare ascorbic acid-containing chitosan study properties and structures important for applicability optimize composition. During formulation films, as polymer basis film used. Ascorbic acid, which provided acidic pH, used in different concentrations (2-5%). The were formulated by solvent casting method. investigated, such physical parameters, force, surface free energy, breaking strength. fine...
Counterfeiting of the products for healing is as old trading, and it difficult to quantify magnitude problem. It known that substandard and/or falsified (SF) medicines are a growing global threat health, they cause serious social economic damage. The EU has strong legal framework medicines, mandatory meet requirements Directive 2011/62/EU. Serialisation prevents SF medicinal from entering distribution chain. present study an extension original idea aims develop laser technology-based method...
Oral mucoadhesive systems, such as polymer films, are among innovative pharmaceutical products. These systems can be applied in swallowing problems and also used geriatrics paediatrics. In our earlier work, we successfully formulated buccal which contained cetirizine-hydrochloride (CTZ) the API. The present study focused on investigating stability permeability of prepared films. films was studied with an accelerated test. During test, thickness, breaking hardness vitro mucoadhesivity were...
One of the most promising emerging innovations in personalized medication is based on 3D printing technology. For use as authorized medications, 3D-printed products require different vitro tests, including dissolution and biocompatibility investigations. Our objective was to manufacture implantable drug delivery systems using fused deposition modeling, tests were performed for assessment these products. Polylactic acid, antibacterial polylactic polyethylene terephthalate glycol, poly(methyl...