A5057062110- Eating Disorders and Behaviors
- Pain Mechanisms and Treatments
- Obesity and Health Practices
- Additive Manufacturing and 3D Printing Technologies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Obesity, Physical Activity, Diet
- Pharmacology and Obesity Treatment
- Respiratory Support and Mechanisms
- Neuropeptides and Animal Physiology
- Healthcare and Venom Research
- High Altitude and Hypoxia
- Helicobacter pylori-related gastroenterology studies
- Augmented Reality Applications
- Essential Oils and Antimicrobial Activity
- Pediatric health and respiratory diseases
- Advanced Numerical Analysis Techniques
- Cognitive Computing and Networks
- Facial Rejuvenation and Surgery Techniques
- Nutrition and Health in Aging
- QR Code Applications and Technologies
- Robotics and Automated Systems
- Advanced Image and Video Retrieval Techniques
- Phytochemistry and Biological Activities
- Hungarian Social, Economic and Educational Studies
- T-cell and B-cell Immunology
University of Debrecen
2012-2024
University of Pecs
2023
Semmelweis University
2003-2021
University of Miskolc
2016
Orszagos Kornyezetegeszsegugyi Intezet
2014-2015
National Institute for Food and Nutrition Science
2010
Harvard University
1992-1993
Beth Israel Deaconess Hospital
1992
Vaginal drug delivery systems can provide a long-term and constant liberation of the active pharmaceutical ingredient even for months. For our experiment, FDM 3D printing was used to manufacture vaginal ring samples from thermoplastic polyurethane filament, which enables fast manufacturing complex, personalized medications. be an excellent alternative instead industrial manufacturing, is complicated time-consuming. In work, printed rings were filled manually with jellified metronidazole or...
The in vivo relevance of functional dichotomy CD4+ Th clones was studied by analyzing the induction mRNA encoding for Th1- (IL-2) and Th2- (IL-4) specific lymphokines a model accelerated (24 h) cardiac allograft (Tx) rejection presensitized rats. polymerase chain reaction-assisted screening total cellular RNA from Tx otherwise untreated sensitized recipients has revealed sequential lymphokine expression, with peak IL-2 (6-12 preceding that IL-4 mRNA, which maximal at time actual loss h)....
The accelerated (24 h) rejection of (LEWxBN)F1 cardiac allografts (Tx) in LEW rats sensitized with BN skin grafts, is abrogated CD4 mAb (BWH-4) administration between (day -7) and heart 0) transplantation (Tx survival ca. 11 days, p < 0.0001). This study analyzed the effects CD4-targeted therapy upon host IgG IgM alloantibody (allo-Ab) within serum by two-color flow cytometry, Tx, immunohistology. These data were correlated mRNA protein production profiles Th1 (IL-2, IFN-gamma) vs Th2 (IL-4)...
Abstract A great deal of experimental evidence has already been accumulated that hyperpolarization‐activated and cyclic nucleotide‐gated cation channels (HCN) expressed by peripheral nerve fibers contribute to the initiation activities leading pain. Complementing these findings, we have recently demonstrated HCN subunit 2 (HCN2) channel protein is also widely axon terminals substance P (SP)‐containing peptidergic nociceptive primary afferents in laminae I‐IIo spinal dorsal horn, postulated...
All known biological functions of the pro-inflammatory cytokine interleukin-1β (IL-1β) are mediated by type 1 interleukin receptor (IL-1R1). IL-1β–IL-1R1 signaling modulates various neuronal including spinal pain processing. Although role IL-1β in processing is generally accepted, there a discussion literature whether exerts its effect on activating or glial IL-1R1. To contribute to this debate, here we investigated expression and cellular distribution IL-1R1 superficial dorsal horn control...
ABSTRACT The uncatalyzed reactions of 2,4‐TDI (2,4‐ toluenediisocyanate ) and MDI (4,4 ′ ‐ diphenylmethane‐diisocyanate with alcohols including butan‐1‐ol, butan‐2‐ol, diethylene glycol monomethylether (DEGME) were studied by high performance liquid chromatography (HPLC) electrospray ionization mass spectrometry (ESI‐MS). carried out at different temperatures from 22°C to 75°C using molar ratios diisocyanates. It was found that the first isocyanate group reacts about 1.5 times faster than...
Abstract Hyperpolarization‐activated cyclic nucleotide‐gated cation channel proteins (HCN1–4), which are potentially able to modulate membrane excitability, abundantly expressed by neurons in spinal dorsal root ganglia (DRG). In the present experiment, we investigated whether HCN2 protein is confined exclusively perikarya of DRG or transported from somata central axons that terminate horn. Using immunohistochemical methods, have demonstrated laminae I‐IIo superficial horn adult rat cord show...
What is obvious in real life may be rather complicated to represent and reproduce a digital environment. A growing number of technologies devices have an associated property called 3D, referring their ability approximating reality. This study presents the forms 3D education ways which using printer affects educational institution.
One of the most promising emerging innovations in personalized medication is based on 3D printing technology. For use as authorized medications, 3D-printed products require different vitro tests, including dissolution and biocompatibility investigations. Our objective was to manufacture implantable drug delivery systems using fused deposition modeling, tests were performed for assessment these products. Polylactic acid, antibacterial polylactic polyethylene terephthalate glycol, poly(methyl...
Abstract We have previously demonstrated that hyperpolarization‐activated and cyclic nucleotide‐gated cation channel subunit 2 (HCN2) is expressed by terminals of peptidergic nociceptive primary afferents in laminae I–IIo the rat spinal dorsal horn. In this study, we investigated possible neurotransmitters postsynaptic targets these HCN2‐expressing afferent superficial horn using immunocytochemical methods. HCN2 widely colocalizes with substance P (SP), HCN2‐positive are also immunoreactive...
Providing additional information for parts or items usually means to enclose it next the object affix on component when that is possible. However, another solution available by gaining benefits of an additive manufacturing technology, 3D printing. This technology makes possible embed onto surface items, example, in forms QR codes. In work Kikuchi et al. (2018), code embedded into CAD models consist B-spline surfaces grooving its dark regions shadow them. The method proposed Peng (2019)...
The rapid advancement of technology and innovation is also impacting education across different levels. rise Artificial Intelligence (AI) beginning to transform in various areas, from course materials assessment systems. This requires educators reconsider how they evaluate students’ knowledge. It crucial understand if what extent assignments can be completed using AI tools. study explores two hypotheses about the risks code-based 3D modeling software potential for students delegate their...
Cognitive impairment and learning ability of the brain are directly linked to synaptic plasticity as measured in changes long-term potentiation (LTP) depression (LTD) animal models diseases. LTD reflects a sustained reduction AMPA receptor content based on targeted clathrin-mediated endocytosis. endocytosis is initiated by dephosphorylation Tyr876 C-terminus AMPAR subunit GluA2. The brain-specific striatal-enriched protein tyrosine phosphatase (STEP) responsible for this process. To identify...
Elméleti háttér: A nyugati kultúrában negatív attitűdök kapcsolódnak az elhízáshoz. Az elhízással kapcsolatos előítéletek már óvodáskortól kezdődően kimutathatóak. előítélet és diszkrimináció káros hatást gyakorolhat elhízott gyermekek serdülők mentális testi egészségére. stigmatizáció típusának mértékének felmérése kulcsfontosságú lehet a megfelelő intervenciós programok kidolgozása szempontjából. Cél: kutatás célja elhízottakkal szembeni potenciális magyarázó változóinak vizsgálata volt...
Finding connections between information or inside tabular data is a challenging task. Therefore, we want to demonstrate the actual state of our three-dimensional visualization tool which helps better understand behind tables in an efficient way.