A5009290484- Cholinesterase and Neurodegenerative Diseases
- Neuroscience and Neuropharmacology Research
- Alzheimer's disease research and treatments
- Drug Solubulity and Delivery Systems
- Nicotinic Acetylcholine Receptors Study
- Memory and Neural Mechanisms
- Computational Drug Discovery Methods
- Receptor Mechanisms and Signaling
- Neuropeptides and Animal Physiology
- Pesticide Exposure and Toxicity
- Analytical Methods in Pharmaceuticals
- Crystallization and Solubility Studies
- Aluminum toxicity and tolerance in plants and animals
- Ion channel regulation and function
- Olfactory and Sensory Function Studies
- Protein purification and stability
- Medicinal Plants and Neuroprotection
- Chemical synthesis and alkaloids
- Polysaccharides Composition and Applications
- Trace Elements in Health
- Photoreceptor and optogenetics research
- Enzyme function and inhibition
- Neurological Disorders and Treatments
- Mitochondrial Function and Pathology
- Advanced Drug Delivery Systems
University of Szeged
2005-2015
University of Göttingen
1992
Centre National de la Recherche Scientifique
1981
Institute of Animal Physiology of the Slovak Academy of Sciences
1968-1972
Consiglio per la ricerca in agricoltura e l’analisi dell’economia agraria
1969-1972
University of Liège
1965
Abstract: The in vivo and vitro effects of A1 on the cholinergic system rat brain were studied. amount accumulated after chronic, intraperitoneal administration aluminum gluconate (Al‐G) or AlCl3, both at a dose 1 mg/ml/100 g body weight, increased frontal parietal cortices, hippocampus, striatum. Significantly decreased choline acetyltransferase activities chronic Al treatment measured cortex, striatum, but not cortex. acetylcholinesterase activity was changed significantly any area...
Abstract— Choline acetyltransferase (ChAc) and acetylcholinesterase (AChE) levels were measured quantitatively in samples from the archi‐ paleocerebellar vermis (Larsell's Lobules IX c,d,‐X, VII‐VIII, respectively) cerebellar peduncles, nuclei white matter of rat guinea pig. Lesions to isolate or areas made some rats effect on enzyme ultrastructure studied. In there was a striking correlation between activity ChAc AChE different areas; thus archicerebellar cortex both enzymes 3–4 times those...
Objective: The purpose of this study was to investigate and quantify flow properties, compressibility, compactibility various pharmaceutical lactose powders found on the market today (DCL-11, DCL-21, M‐200, Flowlac-100, Tablettose 70, 80, 100). Methods: Flow properties were estimated by measuring time, angle repose, Hausner ratio. Particle rearrangement studied using Kawakita's linear model. Compressibility two 'out-of-die' methods: (i) Heckel model (ii) a modified Walker Compactibility...
Apolipoprotein D (apoD) levels were examined in the temporal cortex as well an assessment of location apoD positive cells within brain by immunohistochemical and biochemical methods young control (YC), aged (AC), Alzheimer's demented (AD) probands. Scattered astrocytes oligodendrocytes found throughout white matter immunohistochemistry. ApoD immunoreactivity was also observed In cerebellar YC group. There faint staining scattered cortical a few neurons same contrast, some AC all AD probands...
Betulin and betulinic acid are pentacyclic triterpenes present in the bark of birch tree other vegetal sources. Quantitatively, betulin is more significant than acid; therefore, can be a large feasible source raw material for extraction. used as extracted or, after chemical modification, starting compound its acid, with both substances possessing various interesting pharmacological properties. The purpose this study to analyse content extract, well cytotoxic activity. extraction was done...
During an entire lifetime, sensory axons of regenerating olfactory receptor neurons can enter glomeruli in the bulb and establish synaptic junctions with central neurons. The role played by astrocytes this unique permissiveness is still unclear. Glomerular have been identified immunocytochemistry for glial fibrillary acidic protein S100 proteins at light electron microscopic levels. latter labeling included submicroscopic lamellar filopodial extensions astroglial processes. Cell bodies...