A5001598752- Advancements in Transdermal Drug Delivery
- Advanced Drug Delivery Systems
- Drug Solubulity and Delivery Systems
- RNA Interference and Gene Delivery
- Ocular Surface and Contact Lens
- Bee Products Chemical Analysis
- Glaucoma and retinal disorders
- Dermatology and Skin Diseases
- Crystallization and Solubility Studies
- Lipid Membrane Structure and Behavior
- Neurological Disorders and Treatments
- Gastroesophageal reflux and treatments
- 3D Printing in Biomedical Research
- Pharmaceutical studies and practices
- Respiratory and Cough-Related Research
- Pharmacological Effects of Natural Compounds
- Microencapsulation and Drying Processes
- Analytical Chemistry and Chromatography
- MicroRNA in disease regulation
- Skin Protection and Aging
- Advanced biosensing and bioanalysis techniques
- Computational Drug Discovery Methods
- Potassium and Related Disorders
- Biochemical Analysis and Sensing Techniques
- Neuroscience and Neural Engineering
University of Sarajevo
2019-2024
For many years, researchers have been making efforts to find a manufacturing technique, as well drug delivery system, that will allow for oral of biopharmaceuticals their target site action without impairing biological activity. Due the positive in vivo outcomes this formulation strategy, self-emulsifying systems (SEDDSs) intensively studied last few years way overcoming different challenges associated with macromolecules. The purpose present study was examine possibility developing solid...
Dimenhydrinate (DMH), used to alleviate motion sickness symptoms such as nausea, vomiting, dizziness, and vertigo, encounters limitations in oral pharmaceutical formulations due its poor water solubility bitter taste. Our research hypothesized that inclusion complexation with β-cyclodextrin (β-CD) might address these drawbacks while ensuring the newly formed complexes exhibit no cytotoxic or genotoxic effects on peripheral blood mononuclear cells (PBMCs). Inclusion were prepared using...
Abstract Four natural sweeteners (sucrose, xylitol, fructose, and isomalt) were selected to examine the influence of their qualities amounts on characteristics orodispersible films. Sodium carboxymethylcellulose (2% w/w) was utilized as film-forming polymer 1% w/w glycerol a plasticizer. Films produced through solvent casting method, rendering them suitable for convenient application in community or hospital pharmacy settings. The physicochemical optical properties films analyzed,...
Paediatric and geriatric populations, as well other special patient populations with swallowing problems, require patient-tailored dosage forms. One promising form for these specific is orodispersible films.<br /> When preparing films using sodium carboxymethyl cellulose the film-forming polymer glycerine plasticizer, it essential to determine optimal mixing time speed of casting solution achieve desired transparency/opacity films. In this paper, primary focus on speed, determining how...
To examine the influence of vehicles on stability extemporaneous suspensions proton pump inhibitors (PPIs), to single out formulation most suitable for children, providing appropriate evidence and arguments.A review was performed data identified from Medline, Embase, Science Direct, as well public digital archive PubMed, including reference texts, related field testing PPI suspensions.Fourteen selected formulations are presented discussed. Depending vehicle its composition, which analyzed...
Cationic NLCs represent lipid vesicles bearing cationic lipids on its surface, which leads to electrostatic interactions with negative charges of the nucleic acids such as miRNA and formation a complex protect from inevitable physicochemical biological impacts within blood circulation [1].This study aimed develop cNLCs in order obtain most suitable formulation for further delivery miRNAs.cNLCs containing stearylamine, Precirol® ATO 5 Miglyol® 812 phase different concentrations Poloxamer® 188...
Although homeostasis is a commonly accepted concept, there incontrovertible evidence that biological processes and functions are variable variability occurs in cycles. In order to explain understand dysregulation, which has not been embraced by homeostatic principles, the allostatic model emerged as first serious challenge homeostasis, going beyond its roots. Circadian rhythm predominant variation body, it pattern according many physiological pathological events occur. As strong experimental...
Since glaucoma is a serious health problem, numerous therapeutics are being developed to reduce Intraocular Pressure (IOP) as the only modifiable factor of all symptoms. IOP-lowering agents divided into six groups, each which has specific mechanism action and side effects, focus this article explained in detail. All mentioned formulated eye drops. However, conventional topical drops have significant disadvantages, poor bioavailability patient noncompliance main, novel approaches designing...