A5041315199- Carcinogens and Genotoxicity Assessment
- Nigella sativa pharmacological applications
- Viral Infectious Diseases and Gene Expression in Insects
- Smoking Behavior and Cessation
- Drug Solubulity and Delivery Systems
- Ethnobotanical and Medicinal Plants Studies
- Bone Tissue Engineering Materials
- Essential Oils and Antimicrobial Activity
- Computational Drug Discovery Methods
- Air Quality and Health Impacts
- 3D Printing in Biomedical Research
- Genomic variations and chromosomal abnormalities
- DNA Repair Mechanisms
- Analytical Chemistry and Chromatography
- Mycotoxins in Agriculture and Food
- Genetically Modified Organisms Research
- Plant Genetic and Mutation Studies
- Effects and risks of endocrine disrupting chemicals
- Orthopaedic implants and arthroplasty
- Tissue Engineering and Regenerative Medicine
University of Sarajevo
2019-2024
Lavender and immortelle essential oils (EOs) are widely used to treat a spectrum of human conditions. The aim this study was investigate cyto/genotoxic effects lavender EOs using plant cells (Allium cepa) lymphocytes, as well their antimicrobial potential nine strains bacteria fungi. Our results for showed that the frequency chromosome aberrations (CAs) increased in comparison with controls. For both oils, apoptosis all concentrations, necrosis (0.10/0.30 µl/ml lavender/immortelle,...
Abstract Air pollution, recognized as a human carcinogen, is significant cause of death in industrial and developing countries, Bosnia Herzegovina (B&H) one the leading countries for air pollution—caused rate has poorest urban quality Europe. Despite population decrease, pollution B&H increased due to traffic still intensive use solid fuel heating cooking. Human biomonitoring studies, regarding described have not been conducted before, particularly region Sarajevo. Good health,...
Dimenhydrinate (DMH), used to alleviate motion sickness symptoms such as nausea, vomiting, dizziness, and vertigo, encounters limitations in oral pharmaceutical formulations due its poor water solubility bitter taste. Our research hypothesized that inclusion complexation with β-cyclodextrin (β-CD) might address these drawbacks while ensuring the newly formed complexes exhibit no cytotoxic or genotoxic effects on peripheral blood mononuclear cells (PBMCs). Inclusion were prepared using...
The aim of this study was to determine the cytogenotoxic effects methylparaben, ethylparaben and butylparaben using battery tests in plant cells (Allium cepa assay) human lymphocytes (chromosome aberration test alkaline comet assay). Our results for A. assay showed that none tested parabens an inducing effect on root growth. Mitotic index values decreased with increasing concentration. Ethylparaben (0.10 mg/L) induced a higher number vagrants multipolarity, as well sticky chromosomes (0.50...
Waterpipe, also known as a hookah or narghile, is type of tobacco products consumption device. Recently it has been increasingly popular in Bosnia and Herzegovina the region. Waterpipe consumers are predominantly adolescents young adults. Many them believe slighter harmful effects waterpipes, compared to cigarettes. We aimed determine DNA damage oral leukocytes buccal cells individuals who have smoked waterpipe for more than one year.The study group consisted 40 cigarette non-smokers...
Spontaneous chromosomal aberrations are structural or numerical changes of chromosomes that occur naturally, without exposure to external genotoxic factors. They not inherited, randomly in the karyotype, and do have direct clinical significance. However, they can affect genomic instability disease predisposition. result from DNA replication repair processes errors, typically observed cells actively dividing. may arise due natural be elevated individuals exposed mutagens. We analyzed...