Stéphane Nicolas

ORCID: 0000-0003-0758-9930
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About
Contact & Profiles
Research Areas
  • Genetic Mapping and Diversity in Plants and Animals
  • Handwritten Text Recognition Techniques
  • Image Retrieval and Classification Techniques
  • Genetics and Plant Breeding
  • Advanced Image and Video Retrieval Techniques
  • Horticultural and Viticultural Research
  • Genetic and phenotypic traits in livestock
  • Crop Yield and Soil Fertility
  • Solid State Laser Technologies
  • Wheat and Barley Genetics and Pathology
  • Image Processing and 3D Reconstruction
  • Genetic diversity and population structure
  • Chromosomal and Genetic Variations
  • Developmental Biology and Gene Regulation
  • Fermentation and Sensory Analysis
  • Laser Design and Applications
  • Luminescence Properties of Advanced Materials
  • Laser-Matter Interactions and Applications
  • Advanced Fiber Laser Technologies
  • Photorefractive and Nonlinear Optics
  • Infrared Target Detection Methodologies
  • MicroRNA in disease regulation
  • Genomics and Phylogenetic Studies
  • Plant Physiology and Cultivation Studies
  • Advanced optical system design

Génétique Quantitative et Évolution Le Moulon
2016-2025

AgroParisTech
2012-2025

Centre National de la Recherche Scientifique
2012-2025

Université Paris-Saclay
1998-2025

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2020-2025

Université Grenoble Alpes
2020-2024

CEA LETI
2012-2024

Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2012-2024

CEA Grenoble
2012-2024

Institut Pascal
2024

Abstract Genomic selection refers to the use of genotypic information for predicting breeding values candidates. A prediction formula is calibrated with genotypes and phenotypes reference individuals constituting calibration set. The size composition this set are essential parameters affecting reliabilities. objective study was maximize reliabilities by optimizing Different criteria based on diversity or error variance (PEV) derived from realized additive relationship matrix–best linear...

10.1534/genetics.112.141473 article EN Genetics 2012-08-04

Assessing the genetic variability of plant performance under heat and drought scenarios can contribute to reduce negative effects climate change. We propose here an approach that consisted (1) clustering time courses environmental variables simulated by a crop model in current (35 years × 55 sites) future conditions into six temperature water deficit as experienced maize (Zea mays L.) plants; (2) performing 29 field experiments contrasting across Europe with 244 hybrids; (3) assigning...

10.1104/pp.16.00621 article EN PLANT PHYSIOLOGY 2016-07-19

As for many crops, new high-quality grapevine varieties requiring less pesticide and adapted to climate change are needed. In perennial species, breeding is a long process which can be speeded up by gaining knowledge about quantitative trait loci linked agronomic traits variation. However, due the juvenile period of these establishing numerous highly recombinant populations high resolution mapping both costly time-consuming. Genome wide association studies in germplasm panels an alternative...

10.1186/s12870-016-0754-z article EN cc-by BMC Plant Biology 2016-03-22

The ECPGR European Evaluation Network (EVA) for Maize involves genebanks, research institutions, and private breeding companies from nine countries focusing on the valorization of maize genetic resources across Europe. This study describes a diverse collection 626 local landraces traditional varieties (Zea mays L.) including criteria selection its phenotypic diversity. High-throughput pool genotyping grouped into groups with threshold 0.6 admixture, while 277 accessions were designated...

10.3390/biology13060454 article EN cc-by Biology 2024-06-19

A simple scheme for generation of high power in the midinfrared is demonstrated. By using a 15 W thulium-doped fiber laser emitting at 1907 nm to pump Q-switched Ho:YAG laser, we obtained 9.8 2096 20 kHz pulse repetition rate with excellent beam quality. The output this was used doubly resonant zinc germanium phosphide based optical parametric oscillator, and 5.1 average 3-5 microm range M2 approximately = 1.8.

10.1364/ao.45.003839 article EN Applied Optics 2006-05-24

Chromosomal rearrangements can be triggered by recombination between distinct but related regions. Brassica napus (AACC; 2n = 38) is a recent allopolyploid species whose progenitor genomes are widely replicated. In this article, we analyze the extent to which chromosomal originate from homeologous during meiosis of haploid B. (n 19) genotyping progenies x euploid with molecular markers. Our study focuses on three pairs regions selected for their differing levels divergence (N1/N11, N3/N13,...

10.1534/genetics.106.062968 article EN Genetics 2006-12-07

Although the genetic regulation of recombination in allopolyploid species plays a pivotal role evolution and plant breeding, it has received little recent attention, except wheat (Triticum aestivum). PrBn is main locus that determines number nonhomologous associations during meiosis microspore cultured Brassica napus haploids (AC; 19 chromosomes). In this study, we examined played by recombination. We generated two haploid x euploid populations using B. with differing (and interacting genes)...

10.1105/tpc.108.062273 article EN The Plant Cell 2009-02-01

The migration of maize from tropical to temperate climates was accompanied by a dramatic evolution in flowering time. To gain insight into the genetic architecture this adaptive trait, we conducted 50K SNP-based genome-wide association and diversity investigation on panel American European representatives. Eighteen genomic regions were associated with number early alleles cumulated along these highly correlated Polymorphism vicinity ZCN8 gene, which is closest homologue Arabidopsis major...

10.1371/journal.pone.0071377 article EN cc-by PLoS ONE 2013-08-30

Abstract Association mapping has permitted the discovery of major QTL in many species. It can be applied to existing populations and, as a consequence, it is generally necessary take into account structure and relatedness among individuals statistical model control false positives. We analytically studied power association studies by computing noncentrality parameter tests its relationship with parameters characterizing diversity (genetic differentiation between groups allele frequencies)...

10.1534/genetics.113.159731 article EN Genetics 2014-02-16

Through the local selection of landraces, humans have guided adaptation crops to a vast range climatic and ecological conditions. This is particularly true maize, which was domesticated in restricted area Mexico but now displays one broadest cultivated ranges worldwide. Here, we sequenced 67 genomes with an average sequencing depth 18x document routes introduction, admixture selective history European maize its American counterparts. To avoid confounding effects recent breeding, targeted...

10.1371/journal.pgen.1006666 article EN cc-by PLoS Genetics 2017-03-16

High-throughput re-sequencing, new genotyping technologies and the availability of reference genomes allow extensive characterization Single Nucleotide Polymorphisms (SNPs) insertion/deletion events (indels) in many plant species. The rapidly increasing amount re-sequencing data generated by large-scale genetic diversity projects requires development integrated bioinformatics tools able to efficiently manage, analyze, combine these with genome structure external data. In this context, we...

10.1186/1471-2105-12-134 article EN cc-by BMC Bioinformatics 2011-05-05

A combined metabolomic, biochemical, fluxomic, and metabolic modeling approach was developed using 19 genetically distant maize (Zea mays) lines from Europe America. Considerable differences were detected between the when leaf profiles activities of main enzymes involved in primary metabolism compared. During grain filling, composition appeared to be a reliable marker, allowing classification matching genetic diversity lines. same period, there significant correlation distance carbon...

10.1105/tpc.16.00613 article EN The Plant Cell 2017-04-10

Single Nucleotide Polymorphism (SNP) array and re-sequencing technologies have different properties (e.g. calling rate, minor allele frequency profile) drawbacks ascertainment bias). This lead us to study their complementarity the consequences of using them separately or combined in diversity analyses Genome-Wide Association Studies (GWAS). We performed GWAS on three traits (grain yield, plant height male flowering time) measured 22 environments a panel 247 F1 hybrids obtained by crossing...

10.1186/s12870-019-1926-4 article EN cc-by BMC Plant Biology 2019-07-16

Landraces, that is, traditional varieties, have a large diversity is underexploited in modern breeding. A novel DNA pooling strategy was implemented to identify promising landraces and genomic regions enlarge the genetic of varieties. As proof concept, pools from 156 American European maize representing 2340 individuals were genotyped with an SNP array assess their genome-wide diversity. They compared elite cultivars produced across 20th century, represented by 327 inbred lines. Detection...

10.1111/pbi.14022 article EN cc-by-nc Plant Biotechnology Journal 2023-02-06

Background and Aims Berry weight in the grapevine, as tomato, is variable, ranging from less than 1 g to 10 g. In berry depends on cell number volume but also carpel number. The aim of this work was decipher range variation propose a role for subtraits possibly underlying size highly diverse collection cultivated grapevines. Methods Results Cell division before after anthesis expansion appeared be major determinants flesh between cultivars. Carpel varied cultivars, with two three carpels per...

10.1111/ajgw.12021 article EN Australian Journal of Grape and Wine Research 2013-04-22

Summary Chromosome rearrangements are common, but their dynamics over time, mechanisms of occurrence and the genomic features that shape distribution rate still poorly understood. We used allohaploid Brassica napus (AC, n = 19) as a model to analyze effect on formation diversity meiotically driven chromosome rearrangements. showed B. meiosis leads extensive new structural diversity. Almost every offspring carried unique combination multiple throughout genome, was thus structurally...

10.1111/j.1365-313x.2012.04914.x article EN The Plant Journal 2012-01-23

After having successfully demonstrating a 2-layer face-to-back (F2B) test vehicle (TV), we reached the next level of integration by achieving 3-layer TV with fine-pitch Cu-Cu hybrid bonding (HB) technology and high-density (HD) Through Silicon Via (TSV). Different Cu damascene levels that simulate back-end-of-line (BEOL) layers are used on 300mm wafers to fabricate TV. bonded first two (tier 1 tier 2) within face-to-face (F2F) configuration, backside 2 is thinned down 9 μm. 1x10μm TSVs then...

10.1109/ectc51529.2024.00057 article EN 2024-05-28

Elucidating the genetic components of plant genotype-by-environment interactions is key importance in context increasing climatic instability, diversification agricultural practices and pest pressure due to phytosanitary treatment limitations. The genotypic response environmental stresses can be investigated through multi-environment trials (METs). However, genome-wide association studies (GWAS) MET data are significantly more complex than that single environments. In this context, we...

10.1371/journal.pgen.1011553 article EN cc-by PLoS Genetics 2025-01-10
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