A5067787009- Cystic Fibrosis Research Advances
- Emergency and Acute Care Studies
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Infections and bacterial resistance
- Asthma and respiratory diseases
- COVID-19 and healthcare impacts
- Respiratory Support and Mechanisms
- Antimicrobial Resistance in Staphylococcus
- Diabetes Management and Research
- Nosocomial Infections in ICU
- Respiratory and Cough-Related Research
- NF-κB Signaling Pathways
- IL-33, ST2, and ILC Pathways
- Trauma and Emergency Care Studies
- Viral Infections and Vectors
- Streptococcal Infections and Treatments
- Genetic and rare skin diseases.
- Urinary Tract Infections Management
- Phytochemistry and biological activities of Ficus species
- Tracheal and airway disorders
- Dialysis and Renal Disease Management
- Diabetes and associated disorders
- Dermatological and COVID-19 studies
- Medical research and treatments
Centro Hospitalar de Lisboa Central
2022-2023
Hospital de Dona Estefânia
2022
Centro Hospitalar Lisboa Norte
2010-2021
Royal Brompton Hospital
2015
Hospital de Santa Maria
2008-2013
University of Lisbon
2008-2012
Seacroft Hospital
2008
St James's University Hospital
2008
The mechanism underlying severe asthma with fungal sensitization (SAFS) is unknown. IL-33 important in fungus-induced exacerbations, but its role unexplored.We sought to determine whether children therapy-resistant mediated by IL-33.Eighty-two (median age, 11.7 years; 63% male) were included. SAFS (n = 38) was defined as specific IgE or skin prick test response positivity Aspergillus fumigatus, Alternaria alternata, Cladosporium herbarum. Clinical features and airway immunopathology...
Background During the initial phase of Coronavirus Disease 2019 (COVID-19) pandemic, reduced numbers acutely ill or injured children presented to emergency departments (EDs). Concerns were raised about potential for delayed and more severe presentations an increase in diagnoses such as diabetic ketoacidosis mental health issues. This multinational observational study aimed number presenting EDs across Europe during early COVID-19 pandemic factors influencing this investigate changes severity...
Background Bronchiolitis is a major source of morbimortality among young children worldwide. Non-pharmaceutical interventions (NPIs) implemented to reduce the spread severe acute respiratory syndrome coronavirus 2 may have had an important impact on bronchiolitis outbreaks, as well societal consequences. Discriminating between their respective impacts would help define optimal public health strategies against bronchiolitis. We aimed assess each NPI outbreaks in 14 European countries. Methods...
Cardoso, Bruno Miguel; Dupont, Juliette; Castanhinha, Susana; Ejarque-Albuquerque, Margarida; Pereira, Sónia; Miltenberger-Miltenyi, Gabriel; Oliveira, Graça Author Information
Introdução: a Diabetes Mellitus tipo 1 (DM1) é doença crónica endócrino-metabólica mais frequente em idade pediátrica. Associa-se complicações vasculares e neuropáticas, podendo afectar também o crescimento desenvolvimento. Objectivo: relacionar controlo metabólico duração da com puberdade jovens DM1 seguidos consulta de Endocrinologia Pediátrica um Hospital Central. Material métodos: estudo retrospectivo analítico. Amostra obtida partir dos doentes na Unidade do Santa Maria (HSM) (Lisboa,...
<h3>Introduction</h3> Severe asthma with fungal sensitisation (SAFS) in adults is associated reduced lung function and increased morbidity [<i>EurRespir J</i> 2006;<b>27</b>:615–26, <i>Am J RespirCare Med</i> 2009; <b>179</b>:11–18]. We hypothesised that children severe, therapy-resistant (STRA) symptoms, medication use airway inflammation, function. <h3>Methods</h3> STRA was defined as before [<i>Lancet</i> 2010;<b>376</b>:814–25]. All had been through a detailed assessment to optimise...
Objetivos : Relatar dois casos de edema hemorragico agudo da infância, que consiste numa vasculite rara, caracterizada por lesoes cutâneas purpuricas e periferico, sem envolvimento sistemico (excetuando-se a febre), tem inicio subito, curso benigno evolui espontaneamente para cura. Descricao dos casos: Os autores apresentam criancas do sexo masculino, com 11 12 meses idade, foram atendidos no servico urgencia febre exuberantes agravamento progressivo. O diagnostico infância foi feito...
Introdução: Ao Staphylococcus aureus resistente à meticilina (MRSA) é classicamente reconhecido um papel patogénico no âmbito da fibrose quística (FQ). Objectivos: Avaliação evolução prevalência e incidência colonização por MRSA, impacto clínico ano após o primeiro isolamento, factores de risco padrão resistência antimicrobiana. Métodos: Estudo retrospectivo dos doentes pediátricos colonizados MRSA seguidos centro FQ do Hospital Santa Maria 2003 a 2007. Resultados: O foi isolado em secreções...
Abstract Background To investigate the impact of COVID-19 pandemic and infection prevention measures on children visiting emergency departments across Europe. Methods Routine health data were extracted retrospectively from electronic patient records aged <16 years, presenting to 38 (ED) in 16 European countries for period January 2018 – May 2020, using predefined standardized domains. Observed predicted numbers ED attendances calculated February 2020 2020. Poisson models incidence rate...