- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Pediatric Hepatobiliary Diseases and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Organ Transplantation Techniques and Outcomes
- Pancreatitis Pathology and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Biliary and Gastrointestinal Fistulas
- Liver Disease and Transplantation
- Appendicitis Diagnosis and Management
- Drug Transport and Resistance Mechanisms
- Liver Disease Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Abdominal Trauma and Injuries
- Colorectal Cancer Treatments and Studies
- Colorectal Cancer Screening and Detection
- Cancer Genomics and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Liver physiology and pathology
- Colorectal Cancer Surgical Treatments
- Gastrointestinal disorders and treatments
- Pneumonia and Respiratory Infections
- Renal cell carcinoma treatment
Washington University in St. Louis
2014-2023
Jewish Hospital
2014-2023
Barnes-Jewish Hospital
2014-2023
Alvin J. Siteman Cancer Center
2008-2023
The Ohio State University
2021
Indiana University – Purdue University Indianapolis
2007-2020
University of Michigan
2020
Rush University Medical Center
2020
American College of Surgeons
2000-2017
Massachusetts General Hospital
2017
Abstract Regulatory T cells (Treg) that prevent autoimmune diseases by suppression of self-reactive may also suppress the immune response against cancer. In mice, depletion Treg Ab therapy leads to more efficient tumor rejection. Treg-mediated antitumor responses partly explain poor clinical vaccine-based immunotherapy for human this study, we measured prevalence coexpress CD4 and CD25 in PBLs, tumor-infiltrating lymphocytes, regional lymph node lymphocytes from 65 patients with either...
In Brief Objective: To summarize the current world position on laparoscopic liver surgery. Summary Background Data: Multiple series have reported safety and efficacy of Small medium sized procedures become commonplace in many centers, while major resections been performed with equaling open surgery highly specialized centers. Although field has begun to expand rapidly, no consensus meeting convened discuss evolving Methods: On November 7 8, 2008, 45 experts hepatobiliary were invited...
The use of laparoscopy for liver surgery is increasing rapidly. Second International Consensus Conference on Laparoscopic Liver Resections (LLR) was held in Morioka, Japan, from October 4 to 6, 2014 evaluate the current status laparoscopic and provide recommendations aid its future development. Seventeen questions were addressed. first 7 focused outcomes that reflect benefits risks LLR. These addressed using Zurich-Danish consensus conference model which literature expert opinion weighed by...
To report the first 5-year overall survival results in patients with colorectal carcinoma metastatic to liver who have undergone hepatic resection after staging [18F] fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET).The for cancer metastases without preoperative FDG-PET has been established 19 studies (6070 patients). The median rate these is 30% and not improved over time. detects unsuspected tumor 25% of considered resectable metastasis by conventional staging.From March...
We have previously defined viability limits in a rat transplantation model. All liver allografts stored simple preservation solution (NaCl 0.9%, CaCl2 2 mM) at 4 degrees C for hr or 37 1 were viable upon transplantation, but all those 8 nonviable. Only cold-preserved, nonviable livers showed increased vascular resistance, platelet trapping and an initially low, then high, rise aspartate transaminase (AST) reperfusion, suggesting injury to the microcirculation, with secondary hepatocyte. In...
To compare perioperative outcomes of laparoscopic left-sided pancreatectomy (LLP) with traditional open (OLP) in a multicenter experience.LLP is being performed more commonly limited data comparing results from OLP.Data 8 centers were combined for all cases between 2002-2006. OLP and LLP cohorts matched by age, American Society Anesthesiologists, resected pancreas length, tumor size, diagnosis. Multivariate analysis was using binary logistic regression.Six hundred sixty-seven LPs performed,...
Abstract Since its publication in 2007, the Tokyo Guidelines for management of acute cholangitis and cholecystitis (TG07) have been widely adopted. The validation TG07 conducted terms clinical practice has shown that diagnostic criteria are highly reliable but definition definite diagnosis is ambiguous. Discussion by Revision Committee concluded should be suspected when Murphy's sign, local inflammatory findings gallbladder such as right upper quadrant abdominal pain tenderness, fever...