A5081277628- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Appendicitis Diagnosis and Management
- Biliary and Gastrointestinal Fistulas
- Liver Disease Diagnosis and Treatment
- Amoebic Infections and Treatments
- Pneumonia and Respiratory Infections
- Pancreatitis Pathology and Treatment
- Cancer, Lipids, and Metabolism
- Cancer Cells and Metastasis
- Hepatitis B Virus Studies
- Neuroendocrine Tumor Research Advances
- Neonatal Health and Biochemistry
- Diverticular Disease and Complications
- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Angiogenesis and VEGF in Cancer
- Cancer, Hypoxia, and Metabolism
- Gastrointestinal disorders and treatments
- Liver Disease and Transplantation
- Drug Transport and Resistance Mechanisms
- Abdominal Trauma and Injuries
I-Shou University
2023-2024
E-Da Hospital
2023-2024
Kaohsiung Medical University Chung-Ho Memorial Hospital
2007-2023
GTx (United States)
2023
Yuan's General Hospital
2005-2022
Kaohsiung Medical University
1991-2012
National Taiwan University Hospital
1999
Abstract Since its publication in 2007, the Tokyo Guidelines for management of acute cholangitis and cholecystitis (TG07) have been widely adopted. The validation TG07 conducted terms clinical practice has shown that diagnostic criteria are highly reliable but definition definite diagnosis is ambiguous. Discussion by Revision Committee concluded should be suspected when Murphy's sign, local inflammatory findings gallbladder such as right upper quadrant abdominal pain tenderness, fever...
Abstract Background The Tokyo Guidelines 2007 ( TG 07) first presented the diagnostic and severity grading criteria for acute cholangitis. Subsequently updated in 2013, 13) have been widely adopted throughout world as global standard guidelines. We set out to verify efficacy of these 13 an international multicenter study. Methods reviewed 6,063 patients who were clinically diagnosed with cholangitis Japan Taiwan over a 2‐year period. retrospectively applied, 30‐day mortality was...
Abstract Background The international practice guidelines for patients with acute cholangitis and cholecystitis were released in 2007 (TG07) revised 2013 (TG13). This study investigated updated epidemiology outcomes among on a larger scale the first time. Methods is an multi‐center retrospective observational Japan Taiwan. All consecutive older than 18 years of age given clinical diagnosis by clinicians between 1 January 2011 31 December 2012 enrolled. Those who met diagnostic criteria TG 13...
Abstract Background Although early laparoscopic cholecystectomy is widely performed for acute cholecystitis, the optimal timing of a in clinically ill patients remains controversial. This study aims to determine best practice presenting with cholecystitis focused on disease severity and comorbidities. Methods An international multicentric retrospective observational was conducted over 2‐year period. Patients were divided into four groups: Group A: primary cholecystectomy; B: after...
Serious complications continue to occur in laparoscopic cholecystectomy (LC). The commonly used indicators of surgical difficulty such as the duration surgery are insufficient because they surgeon and institution dependent. We aimed identify appropriate during LC.A total 26 Japanese expert LC surgeons discussed using nominal group technique (NGT) generate a list intraoperative findings that contribute difficulty. Thereafter, survey was circulated 61 experts Japan, Korea, Taiwan....
Vascular endothelial growth factor (VEGF) can be produced by monocytes and cells. It plays important role in angiogenesis vascular permeability. The phenomenon of extensive plasma leakage into various serous cavities the body is a cardinal symptom dengue hemorrhagic fever (DHF). This study was performed to investigate VEGF patients with DHF. Plasma samples collected from 53 (DF) (including 14 DHF), 5 additional subjects non-dengue febrile illness as controls were tested for levels using...
Tokyo Guideline 2013 (TG13) proposed three drainage techniques for the treatment of acute cholecystitis. We evaluated clinical efficacy and adverse events between percutaneous transhepatic intervention (PTGBI) including gallbladder (PTGBD) aspiration (PTGBA) endoscopic transpapillary (EGBD).A cohort study was performed using propensity score matching to reduce selection bias. This involved analysis collected data 1,764 patients who underwent PTGBI EGBD.Propensity extracted 330 pairs...
In this study, we try to compare the benefit of laparoscopic versus open operative procedures. Patients and Methods . One hundred sixteen patients underwent liver resection (LR) another 208 went for (OR) hepatocellular carcinoma (HCC). Patients' selection or approach was not randomized. Results The CLIP score LR OR 0.59 ± 0.75 0.86 1.04, respectively, (). operation time 156.3 308.2 190.9 79.2 min groups, respectively. necessity blood transfusion found in 8 (6.9%) 106 (50.9%) groups. resumed...
Since the publication of Tokyo Guidelines (TG13) for management acute cholecystitis (AC), multidirectional studies have been published. However, epidemiological research about AC with big data was not projected. The aim this study to reveal actual clinical conditions AC.The designed as an international multicenter retrospective in Japan and Taiwan from 2011 2013. factors investigated comprised related demographic, history, physical examinations, laboratory imaging findings. Based on these...
The collaborative multicenter retrospective study of acute cholecystitis (AC) was performed in Japan and Taiwan. aim for this evaluation the clinical value TG13 severity grading AC.The designed as an international AC from 2011 to 2013. Based on data, we investigated by analyzing correlations between grade prognosis, surgical procedures, histopathology, organ dysfunction prognosis.An investigation revealed that 30-day overall mortality rate 1.1% Grade I, 0.8% II, 5.4% III. III significantly...
During mitosis, 2 centrosomes ensure accurate assembly of bipolar spindles and fidelity the chromosomal segregation. The presence more than copies during mitosis can result in formation multipolar spindles, unbalanced chromosome segregation, aneuploidy. Recent studies have provided evidence that centrosome hyperamplification plays a pivotal role carcinogenesis. Using immunofluorescence analysis with gamma-tubulin pericentrin antibodies, paraffin-embedded sections from 40 malignant biliary...