Lixin Zhu

ORCID: 0000-0003-0780-4055
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About
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Research Areas
  • Quantum Dots Synthesis And Properties
  • Nanocluster Synthesis and Applications
  • Advanced Photocatalysis Techniques
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Epigenetics and DNA Methylation
  • Nanoplatforms for cancer theranostics
  • Cancer-related gene regulation
  • Chalcogenide Semiconductor Thin Films
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cancer-related molecular mechanisms research
  • Advanced biosensing and bioanalysis techniques
  • Ferroptosis and cancer prognosis
  • 2D Materials and Applications
  • Perovskite Materials and Applications
  • Liver Disease Diagnosis and Treatment
  • Copper-based nanomaterials and applications
  • Cancer, Hypoxia, and Metabolism
  • Plasmonic and Surface Plasmon Research
  • Semiconductor materials and devices
  • Organ Transplantation Techniques and Outcomes
  • Carbon and Quantum Dots Applications
  • RNA modifications and cancer
  • Cell Adhesion Molecules Research
  • Wnt/β-catenin signaling in development and cancer
  • Cholangiocarcinoma and Gallbladder Cancer Studies

First Affiliated Hospital of Anhui Medical University
2015-2025

Anhui Medical University
2015-2025

Zhujiang Hospital
2025

Southern Medical University
2025

Harbin Institute of Technology
2024

Shaanxi Normal University
2023

Hefei University
2015-2021

Union Hospital
2005

Huazhong University of Science and Technology
2005

University of Hong Kong
1995-1996

The visible-light-driven CO2 reduction efficiency is largely restrained by the negative photoabsorption and high recombination rate of electron–hole pairs. It an effective method to increase photoreduction doping alkali metal elements engineer electronic properties catalyst. Here, we report a new study on potassium-doped g-C3N4 (K-CN) being used for irradiated visible light. DFT calculations XPS tests show that potassium interlayer doping, changing structure g-C3N4. higher ID/IG value...

10.1021/acssuschemeng.0c01151 article EN ACS Sustainable Chemistry & Engineering 2020-05-13

As a rising star in two-dimensional (2D) layered materials, transition metal dichalcogenides (TMDs) have attracted tremendous attention for their potential applications nanoelectronics, optoelectronics and photonics. Driven by the high standards of practical devices, alloying theory has been proposed modulating electronic structure TMDs materials as well physical chemical properties. To date, however, very limited alloy can be synthesized vapor deposition (CVD) band gap range achieved....

10.1039/c5nr02515j article EN Nanoscale 2015-01-01

Attention on semiconductor nanocrystals have been largely focused because of their unique optical and electrical properties, which can be applied as light absorber luminophore. However, the band gap structure engineering nanomaterials is not so easy finite size. Here we demonstrate an approach for preparing ternary AgInS2 (AIS), quaternary AgZnInS (AZIS), AgInS2/ZnS AgZnInS/ZnS nanocompounds based cation exchange. First, pristine Ag2S quantum dots (QDs) with different sizes were synthesized...

10.1021/acsami.6b07768 article EN ACS Applied Materials & Interfaces 2016-08-30

Abstract Photoreduction of CO 2 without photosensitizers and scavengers runs into the development bottleneck for lack excellent photocatalysts ambiguous reduction mechanism. Herein, an ultrathin CoO layer containing Zn‐dopants O‐vacancies (V o ‐Zn‐CoO) is designed as archetype to explore influence mechanism Zn on in nanolayer photoreduction. DFT calculations illustrate that not only reduce formation barriers *COOH *CO intermediates, but also form π‐back‐bonding with stimulating CH 4...

10.1002/adfm.202109336 article EN Advanced Functional Materials 2021-12-29

Cu doped Zn–In–S/ZnS QDs were synthesized for labeling the cytoplasm and their multiple peak emission mechanisms proposed.

10.1039/c4tb01957a article EN Journal of Materials Chemistry B 2015-01-01

Here we demonstrate a novel and facile strategy of highly luminescent water-soluble Zn-doped AgIn5S8 (ZAIS) nanocrystals ZAIS/ZnS core/shell structures, which were based on hydrothermal reaction between the acetate salts corresponding metals sulfide precursor in presence l-cysteine at 110 °C Teflon-lined autoclave. The photoluminescent (PL) emission wavelength can be conveniently tuned from 560 to 650 nm by tailoring stoichiometric ratio [Ag]/[Zn]. as prepared characterized systematically...

10.1021/ic502600u article EN Inorganic Chemistry 2015-01-16

In this work, we prepared ultrathin MoS<sub>2</sub> nanosheets with exposed active edge sites and high electric conductivity that can sufficiently absorb light in the visible region to enable solar energy conversion.

10.1039/c8nr10320h article EN Nanoscale 2019-01-01

AIM:To investigate the promoter methylation status and mRNA expression of DKK-3 WIF-1 gene in hepatocellular carcinoma (HCC).METHODS: acted as Wnt-antagonists t umor suppressors, but hypermethylation low activated Wnt signaling aberrantly induced development HCC.Methylation was investigated using specific polymerase chain reaction (PCR) tumor adjacent non-cancerous tissues from 33 HCC patients 20 normal liver served control.The also determined by real-time quantitative reverse transcriptase...

10.3748/wjg.15.2595 article EN cc-by-nc World Journal of Gastroenterology 2009-01-01

Despite the fact that Au-Ag hollow nanoparticles (HNPs) have gained much attention as ablation agents for photothermal therapy, instability of Ag element limits their applications. Herein, excess Au atoms were deposited on surface a HNP by improving reduction power l-ascorbic acid (AA) and thereby preventing reaction between HAuCl4 in alloy nanostructure. Significantly, obtained Au-Ag@Au HNPs show excellent chemical stability an oxidative environment, together with remarkable increase...

10.1021/acsami.5b08305 article EN ACS Applied Materials & Interfaces 2015-09-15

We report on the synthesis of water dispersible Zn<sub>3</sub>In<sub>2</sub>S<sub>6</sub> and Ag–Zn–In–S QDs their relaxation dynamics.

10.1039/c6tb02297a article EN Journal of Materials Chemistry B 2016-01-01

Osteosarcoma (OS) is the most common primary malignant bone tumor. Recent evidence suggests that novel long noncoding RNA DHRS4 antisense 1 (DHRS4-AS1) serves an important role in cancer progression and metastasis. However, its function molecular mechanism OS remain largely unknown. In present study, DHRS4-AS1 expression was detected cells by quantitative PCR. Gain- loss-of-function experiments were conducted to study effects of on proliferation apoptosis cells. The potential examined...

10.1038/s41598-025-87246-7 article EN cc-by-nc-nd Scientific Reports 2025-01-23

Cancer stem cells (CSCs) possess the ability to self-renew and exhibit high differentiation potential, they have been proven be responsible for maintenance, growth, metastasis of tumors. As such, accurate identification targeted therapy CSCs are great importance in clinical treatment. Here, a dual-targeted light-responsive nanoprobe is presented, utilizing reconstructed mesoporous SiO2 binary fatty acid eutectic mixture gold porous shell. The shell sustains large absorption cross-section,...

10.1039/d4tb02508c article EN Journal of Materials Chemistry B 2025-01-01

Chimeric antigen receptor (CAR) T cell therapy has shown promising responses in patients with refractory or relapsed aggressive B-cell malignancies that are resistant to conventional chemotherapy stem transplantation. A potentially combinatorial therapeutic strategy may be the inhibition of anti-apoptotic Bcl-2 family proteins, overexpressed most cancer cells. In this study we investigated combination 3rd-generation CD19.CAR-T cells and BH3 mimetics venetoclax, a inhibitor, S63845, Mcl-1...

10.3389/fimmu.2020.608167 article EN cc-by Frontiers in Immunology 2020-12-09

We prepared novel photoanodes structured as FTO/ZnO nanoflowers/ZnTiO3/CdS/CdTeS/ZnS quantum dots (QDs) with highly exposed large specific area and energy coupling. The design of the photoanode expressed significant enhanced photoelectrochemical (PEC) performance such improved absorption efficiency, reduced recombination rate, charge transportation state, resulting in a increase photoelectron current. multinanoheterostructures provides high photocatalytic activity maximum photocurrent...

10.1021/acs.jpcc.7b04701 article EN The Journal of Physical Chemistry C 2017-09-06

A multifunctional nanoprobe (based on Au [email protected]@Fe3O4) is developed for tumor targeted imaging and photothermal therapy. nanostars Fe3O4 are connected with polydopamine, combined antibody-FITC or antibody-quantum dots in vitro vivo fluorescence labeling (FL), respectively, to form the composite nanoprobe. The shape lattice structure of were confirmed TEM, HRTEM XRD experiments. Compared other protected]3O4 probes, protected]@Fe3O4 has a low conversion threshold. corresponding pure...

10.1016/j.matdes.2021.109707 article EN cc-by-nc-nd Materials & Design 2021-04-16

Cancer stem cells, which are a population of cancer cells sharing common properties with normal have strong self-renewal ability and multi-lineage differentiation potential to trigger tumor proliferation, metastases, recurrence. From this, targeted therapy for may be one the most promising strategies comprehensive treatment tumors in future. We design facile approach establish colon cells-selective fluorescent probe based on low-density lipoprotein (LDL) novel AgGaxIn(1–x)S2 quantum dots...

10.1021/acsami.9b00121 article EN ACS Applied Materials & Interfaces 2019-02-19
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