A5068720597- Acute Myeloid Leukemia Research
- Hematological disorders and diagnostics
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Hemoglobinopathies and Related Disorders
- Digital Imaging for Blood Diseases
- Hematopoietic Stem Cell Transplantation
- Chronic Lymphocytic Leukemia Research
- Lymphoma Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Clinical Laboratory Practices and Quality Control
- Chronic Myeloid Leukemia Treatments
- Platelet Disorders and Treatments
- Blood groups and transfusion
- Erythrocyte Function and Pathophysiology
- Multiple Myeloma Research and Treatments
- Erythropoietin and Anemia Treatment
- Immunodeficiency and Autoimmune Disorders
- Blood disorders and treatments
- Histone Deacetylase Inhibitors Research
- Complement system in diseases
- Blood properties and coagulation
- Neutropenia and Cancer Infections
- Eosinophilic Disorders and Syndromes
- AI in cancer detection
- COVID-19 Clinical Research Studies
Università Cattolica del Sacro Cuore
2016-2025
Agostino Gemelli University Polyclinic
2007-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2009-2023
University of the Sacred Heart
2019-2020
Engineering (Italy)
2016
Odense University Hospital
2016
Catholic University of America
1993-2015
Policlinico Umberto I
2014
National and Kapodistrian University of Athens
2010
Centro di Riferimento Oncologico della Basilicata
2009
Summary These guidelines provide information on how to reliably and consistently report abnormal red blood cells, white cells platelets using manual microscopy. Grading of nomenclature a brief description the are provided. It is important that all countries in world use consistent reporting cells. An international group morphology experts have decided these consensus opinion. For some cell abnormalities, it was parameters produced by automated haematology analyser might be more accurate less...
Schistocytes are fragments of red blood cells (RBCs) produced by extrinsic mechanical damage within the circulation. The detection schistocytes is an important morphological clue to diagnosis thrombotic microangiopathic anemia (TMA). Reporting criteria between different laboratories, however, not uniform, owing variability shape and nature fragments, as well subjectivity heterogeneity in their assessment. Lack standardization may lead inconsistency or misdiagnosis, thereby affecting...
Summary This revision is intended to update the 1994 ICSH guidelines. It based on those guidelines but updated include new methods, such as digital image analysis for blood cells, a flow cytometric method replace reference manual 400 cell differential, and numerous indices not identified morphologically are introduced. Haematology analysers becoming increasingly complex with technological advancements in instrumentation more quantitative parameters being reported complete count. imperative...
Quantitative hematologic abnormalities have been described in the first patient studies of COVID-19, disease caused by SARS-CoV-2 virus, currently responsible for a rapidly spreading pandemic, worldwide infection with high mortality rate. In severe cases, progresses, through subsequent phases, from an upper respiratory tract local and general flu-like symptoms to viral pneumonia hyperinflammatory host reaction, which leads acute distress multi-organ failure. The most common hematological...
Epigenetic changes play a role and cooperate with genetic alterations in the pathogenesis of myelodysplastic syndromes (MDS). We conducted phase II multicenter study on combination DNA-methyltransferase inhibitor 5-azacytidine (5-AZA) histone deacetylase valproic acid (VPA) patients higher risk MDS.We enrolled 62 MDS (refractory anemia excess blasts, 39 patients; refractory blasts transformation, 19 chronic myelomanocytic leukemia (CMML), 4 patients) an International Prognostic Scoring...
Chronic myelomonocytic leukemia (CMML) is a complex clonal hematological disorder classified among myelodysplastic (MDS)/myeloproliferative neoplasms. Prognosis poor and there lack of effective treatments. The hypomethylating agent decitabine has shown activity against MDS elderly acute myeloid leukemia, but little data focusing specifically on its efficacy in CMML. In this prospective, phase 2 Italian study, CMML patients received intravenous 20 mg/m2 per day Days 1-5 28-day treatment...
In myelodysplastic syndromes (MDS), severe thrombocytopenia is associated with poor prognosis. This multicenter trial presents the second-part long-term efficacy and safety results of eltrombopag in patients low-risk MDS thrombocytopenia.In this single-blind, randomized, placebo-controlled, phase-II adult International Prognostic Scoring System low- or intermediate-1-risk MDS, a stable platelet (PLT) count (<30 × 103/mm3) received placebo until disease progression. Primary end points were...
Electronic noses (e-noses), artificial sensor systems generally consisting of chemical arrays for the detection volatile compound profiles, have potential applications in respiratory medicine. We assessed within-day and between-day repeatability an e-nose made from 32 sensors patients with stable chronic obstructive pulmonary disease (COPD). also compared e-nose, fraction exhaled nitric oxide (FENO) function testing. Within-day was two breath samples collected 30 min seven days apart,...
Summary An evaluation of the significance specified dyserythropoietic features in suspected myelodysplastic syndrome ( MDS ) and acute myeloid leukaemia with erythroid dysplasia was made by means 100 electronic images bone marrow erythroblasts from each 20 subjects: 11 a neoplasm, six another condition that could cause three healthy controls. The carried out independently seven experienced haematologists/haematopathologists who were blinded to diagnosis. majority listed World Health...
We aimed at comparing exhaled and non-exhaled non-invasive markers of respiratory inflammation in patients with chronic obstructive pulmonary disease (COPD) healthy subjects define their relationships smoking habit. Forty-eight stable COPD who were ex-smokers, 17 current smokers, 12 smokers ex-smokers included a cross-sectional, observational study. Inflammatory outcomes, including prostaglandin (PG) E2 15-F2t-isoprostane (15-F2t-IsoP) concentrations breath condensate (EBC) sputum...