A5073384069- Reproductive System and Pregnancy
- Organ and Tissue Transplantation Research
- Immunotherapy and Immune Responses
- Cancer Cells and Metastasis
- Pharmacological Effects of Natural Compounds
- Microtubule and mitosis dynamics
- Cardiac Health and Mental Health
- Cell Adhesion Molecules Research
- Tissue Engineering and Regenerative Medicine
- Traditional Chinese Medicine Analysis
- Cardiac Ischemia and Reperfusion
- Psoriasis: Treatment and Pathogenesis
- Circular RNAs in diseases
- Aortic Disease and Treatment Approaches
- Cancer Immunotherapy and Biomarkers
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Ginseng Biological Effects and Applications
- Transplantation: Methods and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Blood Pressure and Hypertension Studies
- Endometriosis Research and Treatment
Tianjin Fourth Central Hospital
2018-2024
Tianjin Medical University
2018-2023
Nankai University
2018
Tianjin Medical University General Hospital
2018
Endometrial regenerative cells (ERCs) are a new type of mesenchymal-like stromal cells, and their therapeutic potential has been tested in variety disease models. SDF-1/CXCR4 axis plays chemotaxis role stem/stromal cell migration. The aim the present study was to investigate immunomodulation ERCs on experimental colitis. presence or absence pretreatment SDF-1 AMD3100 examined both vitro culture system dextran sulphate sodium-induced colitis mice. results showed that increased expression...
A tumor occurs because of abnormal cell multiplication caused by many variables like a significant disturbance in the regulation growth and instability chromosome mitosis. Budding uninhibited benzimidazoles 1 (BUB1), BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B), budding 3 (BUB3) are key regulators mitosis, their expression is highly correlated with breast cancer (BrCa), sarcoma, hepatic carcinoma, other malignant tumors. However, occurrence BUBs (BUB1, BUB1B, BUB3) development...
Vasculopathy is one of the primary pathological changes in chronic rejection vascularized allograft transplantation. Endometrial regenerative cells (ERCs) are mesenchymal-like stromal with immunosuppressive effect. B7-H1 a negative costimulator that mediates active immune suppression. The aim this study was to investigate requirement immunoregulation ERCs preventing transplant vasculopathy aorta allografts. results showed expression on upregulated by IFN- γ dose-dependent manner and it...
INTRODUCTION: The tumor cells could escape from the immune elimination through immunoediting mechanisms including generation of immunosuppressive or immunoregulative cells. By contrast, allograft transplantation activate system and induce a strong allogenic response. aim this study was to investigate efficacy skin in inhibition growth activation METHODS: Full-thickness performed C57BL/6 (H-2b) donors BALB/c (H-2d) recipients that were receiving subcutaneous injection isogenic CT26 colon...
<title>Abstract</title> The use of antidepressants has been increasing in recent years, however, the connection between antidepressant and risk venous thromboembolism inconsistent, with earlier research yielding contradictory findings about impact on thromboembolism. Mendelian randomization was used to determine if affects at genetic level. Genetic tools linked a large genome-wide level (P < 5e-7) were selected from FinnGen consortium. We acquired pooled VTE data European Bioinformatics...
Objective: This study used network pharmacology and molecular docking technology to explore the mechanism of Panax notoginseng in treatment disseminated intravascular coagulation. Methods: The main active components targets were screened by TCMSP database, DIC-related obtained from GeneCards database. PPI was constructed String Cytoscape, GO gene analysis KEGG pathway enrichment performed DAVID, AutoDock software. Results: Eight compounds 51 potential therapeutic Sanqi screened. key include...
Objective The aim of this study was to evaluate the effect human umbilical cord mesenchymal stem cell transplantation on degree intima, middle membrane and lumen stenosis after abdominal aorta injury in rabbits. Methods Twenty male 20 New Zealand white rabbits were divided into control group experimental with each 10 rabbits. The models made by balloon dilation two groups. In group, 1×107/kg cells injected vascular rabbit from side hole catheter. same amount normal saline method. 4...
Objective To explore the effect of LncRNA HOXD-AS1 on radiosensitivity H460 cells by targeting regulation miR-454-3p expression. Methods H460 were irradiated with 0, 2, 4, 6 and 8 Gy, expression levels detected qRT-PCR. Cell apoptosis rate measured flow cytometry experiments. cloning experiments used to detect cell radiosensitivity. The protein Caspase-3, Cyclin D1 γ-H2AX Western blot. Results The in was significantly increased after X-ray irradiation (P<0.05), while decreased...