A5073874275- Neonatal Respiratory Health Research
- Neonatal Health and Biochemistry
- Metabolism and Genetic Disorders
- Neonatal and fetal brain pathology
- Neonatal and Maternal Infections
- Infant Nutrition and Health
- Hemoglobinopathies and Related Disorders
- Infant Development and Preterm Care
- Virology and Viral Diseases
- Breastfeeding Practices and Influences
- Syphilis Diagnosis and Treatment
- Bacterial Infections and Vaccines
- COVID-19 Impact on Reproduction
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Congenital Heart Disease Studies
- Congenital Diaphragmatic Hernia Studies
- Vitamin D Research Studies
- Computational Drug Discovery Methods
- Preterm Birth and Chorioamnionitis
- Parvovirus B19 Infection Studies
- Infections and bacterial resistance
- Folate and B Vitamins Research
- Methemoglobinemia and Tumor Lysis Syndrome
- Genetic Syndromes and Imprinting
- Parathyroid Disorders and Treatments
King George's Medical University
2015-2025
Maharani Laxmi Bai Medical College
2023
Saint Peter's University Hospital
2019-2020
Indian Institute of Technology Jammu
2020
Medanta The Medicity
2020
Ganesh Shankar Vidyarthi Memorial Medical College
2020
Rutgers, The State University of New Jersey
2019
Institute of Medical Sciences
2018
Dr. Ram Manohar Lohia Institute of Medical Sciences
2010
Era's Lucknow Medical College and Hospital
2010
We present the case of a toddler displaying neuroregression post-acute gastroenteritis, initially suggesting neurodegenerative disorders. Further investigations showed atypical results—neuroimaging was inconsistent with suspected disorders, while fundus evaluation, evoked potentials and nerve conduction velocity were normal. Specialised tests using gas chromatography mass spectrometry tandem identified methylmalonic acidaemia (MMA), implicating abnormal neurometabolism. Early diagnosis...
The diagnosis of respiratory distress syndrome (RDS) is largely clinical with the support a chest X-ray. Lung ultrasound (LUS) emerging as reliable bedside technique to evaluate RDS. To determine LUS for preterm neonates ≤34 weeks gestation admitted within 12 h birth suspicion RDS and compare lung USG score X-ray predict need surfactant administration. This prospective observational study was conducted among 67 our NICU. Neonates underwent examination, followed promptly by LUS. decision...
Background India has set a goal to eliminate measles and rubella/Congenital Rubella Syndrome (CRS) by 2023. Towards this goal, conducted nationwide supplementary immunization activity (SIA) with measles-rubella containing vaccine (MRCV) targeting children aged between 9 months <15 years established hospital-based sentinel surveillance for CRS. Reliable data about incidence of CRS is necessary monitor progress towards the elimination goal. Methods We serosurveys in 2019–20 among pregnant...
ObjectivesIndia shares largest burden of congenital birth defects (CBDs) in the world. There is paucity data on CBDs our region country.MethodsThis was a hospital based observational study to find incidence, risk factors and outcome among live neonates.ResultsOf 7,075 babies, 92 had 124 CBDs, making incidence 1.3%. The system predominantly involved musculoskeletal (52.2%) followed by central nervous (28.3%), genitourinary (26.1%). Among single talipes equino varus (27.4%) commonest spina...
Background: Oral application of mother's own milk (MOM) in very low birth weight (VLBW) neonates may provide an effective method cleaning the oral cavity and influencing immunocompetent cells there. Methods: A double-blind randomized controlled trial was conducted a tertiary level neonatal unit on VLBW neonates; that is, with <1,500 g, hospitalized within 72 hours birth. The intervention care MOM. primary objective to observe effect MOM late onset sepsis (LOS) also mortality, days attain...
We report a successful case where newborn with transfusion-related acute lung injury following an exchange transfusion was effectively treated using conservative methods, eliminating the need for surfactant therapy. Very few instances of this complication have been documented globally. A low birth weight, small gestational age, term neonate, diagnosed hyperbilirubinaemia due to Rh incompatibility, experienced sudden respiratory distress in form severe retractions, tachypnoea and cyanosis 3...
In this paper, we apply the long short-term memory (LSTM), an advanced recurrent neural network based machine learning (ML) technique, to problem of transmitter selection (TS) for secrecy in underlay small-cell cognitive radio with unreliable backhaul connections. The communication scenario under consideration has a secondary that shares same spectrum primary agreement always maintain desired outage probability constraint network. Due interference from common all transmissions, rates...
BackgroundIn India, facility-based surveillance for congenital rubella syndrome (CRS) was initiated in 2016 to estimate the burden and monitor progress made control. We analyzed data 2016–2021 from 14 sentinel sites describe epidemiology of CRS.MethodWe distribution suspected laboratory confirmed CRS patients by time, place person characteristics. compared clinical signs discarded case-patients find independent predictors using logistic regression analysis developed a risk prediction...
The phenotypical profile of cardiovascular malformations in patients with congenital rubella syndrome (CRS) is varied. We aimed to describe the cardiac defects among CRS detected sentinel surveillance India during 2016-22.Sentinel sites enrolled infants suspected based on presence defects, hearing impairment, eye signs, or maternal history febrile rash illness. Suspected cases underwent detailed systemic examination, including echocardiography and serological investigation for rubella....
The mortality of neonatal pyogenic meningitis is reduced to 10–15%, but morbidity unchanged. Primary objective determine the outcome, i.e. death or abnormal neurological examination (NE) at discharge and developmental quotient (DQ) 3 months. Secondary find predictors poor outcome. In all, 89 neonates enrolled, 10 expired 24 had NE discharge. A total 59 came for follow up, 13 DQ < 70. Prolonged shock (odds ratio, OR: 8.28; p = 0.001), coma (OR: 4.3; seizures 14; 0.012), mechanical ventilation...
ObjectivesThe primary objective was to determine the outcome, in terms of mortality and development bilirubin encephalopathy, neonates with severe hyperbilirubinemia. The secondary possible risk factors for acute encephalopathy (ABE).MethodsConsecutive >35 weeks gestation admitted Neonatal Intensive Care Unit (NICU) a serum >20 mg% first 72 h life or >25 later were enrolled study. clinical demographic characteristics recorded. Neonates treated phototherapy exchange transfusion as...
Hydrocephalus is an abnormal excessive accumulation of cerebrospinal fluid (CSF) in the cavity and spaces brain. Endoscopic third ventriculostomy (ETV) has been established treatment modality for congenital hydrocephalus. However, very young infants, results are challenging. In our study, we have evaluated whether ETV really offers acceptable complication-free postoperative course.To study complication mortality rate infants having hydrocephalus treated with ETV.This a single-center...
Background Mother's milk is the best for neonates. Preterm very low birthweight (VLBW) neonates face many challenges leading to rates of breastfeeding at discharge. Aims (i) To determine proportion <32 weeks preterm VLBW who are exclusively breastfed (EB) discharge and (ii) determinants exclusive (EBF) Methods An observational study was conducted a duration 1 year, from May 2019 April 2020 in tertiary care neonatal intensive unit (NICU) North India. Consecutive admitted within 72 h birth...
Problem consideredThe gold standard for postnatal growth preterm neonates is their intrauterine standard. Extra uterine restriction (EUGR) implies weight less than minus 2 Z scores at discharge.1Clark R.H. Thomas P. Peabody J. Extrauterine remains a serious problem in prematurely born neonates.Pediatrics. 2003; 111: 986-990Crossref PubMed Scopus (414) Google ScholarMethodsA prospective observational study of admitted the level III neonatal unit tertiary care teaching hospital. Growth...
We performed a prospective observational study of 52 patients who were clinically suspected cervical spondylotic myelopathy (CSM), based on the modified Japanese Orthopaedic Association (mJOA) score, and referred for magnetic resonance imaging (MRI) spine.To evaluate quantitative parameters diffusion tensor (DTI) matrix (fractional anisotropy [FA] apparent coefficient [ADC] values) determine subsequent correlation with clinical assessment disease severity in CSM.Conventional MRI is modality...
ObjectivesTo determine the prevalence and predictors of Retinopathy prematurity (ROP) severe ROP.MethodsA prospective observational study (April 2019–May 2020) was conducted at a tertiary care center in preterm newborns with; 1) birth-weight <2000 g or gestation <34 weeks 2) 34–36 with risk factors that predispose to ROP.ResultsA total 340 were screened. ROP diagnosed 63 (18.5%), which 8 (2.4%) had ROP. 30.2%, 63.5%, 9.5% babies stage 1, 2, 3 ROP, respectively. Perinatal for assessed using...
ObjectiveTo assess etiology, clinical profile, and outcome of pathological neonatal unconjugated hyperbilirubinemia, including various Rhesus (Rh) blood group incompatibilities.MethodsThis was a prospective observational study 200 neonates, with hyperbilirubinemia requiring phototherapy and/or exchange transfusion, presented at tertiary care unit during August 2011 to July 2012. Detailed history, physical examination, laboratory work-up were performed. In case, if major incompatibility found...
Chryseobacterium species are widely distributed in nature and can rarely cause human infection. Few cases reported hospitalized patients immunocompromised hosts with indwelling devices associated comorbidities. usually multidrug resistant. We describe 2 of indologenes-associated pneumonia neonates review the published infant cases.
Background: Neonatal sepsis is a continuing problem causing significant burden on health care, especially in developing world. As blood culture has low sensitivity diagnosis of neonatal sepsis, strong clinical suspicion along with combination different laboratory tests required. The data available for extensively studied acute phase reactant, procalcitonin (PCT) remains controversial. This study was done to assess role PCT alone and diagnosing sepsis.Methods: Blood samples 275 neonates...
<title>Abstract</title> Objective Circulating homocysteine and Rubella infection are independent risk factors for congenital heart disease (CHD). The primary objective of the study was to assess association serum levels in cases CHD healthy controls secondary with rubella among cases. Methods This case-control conducted King George’s Medical University, Lucknow. Total 245 echo-graphically confirmed age-gender matched aged 0–11 months were recruited from outpatient clinic wards paediatric...