A5062841892- Down syndrome and intellectual disability research
- Family and Disability Support Research
- Dementia and Cognitive Impairment Research
- Autism Spectrum Disorder Research
- Sleep and Work-Related Fatigue
- Cerebral Palsy and Movement Disorders
- Forest Biomass Utilization and Management
- Alzheimer's disease research and treatments
- Adolescent and Pediatric Healthcare
- Disability Rights and Representation
- Mechanical Engineering Research and Applications
- Chronic Disease Management Strategies
- Child Nutrition and Feeding Issues
- Mechanical and Thermal Properties Analysis
- Thermoregulation and physiological responses
- Physical Education and Training Studies
- Ergonomics and Musculoskeletal Disorders
- Occupational Health and Safety in Workplaces
- Public health and occupational medicine
- Sports Performance and Training
- Genetics and Neurodevelopmental Disorders
- Workplace Health and Well-being
- Ergonomics and Human Factors
- Disability Education and Employment
- Occupational exposure and asthma
Illinois College
2025
University of Illinois Urbana-Champaign
2025
University of Illinois Chicago
2019-2024
University of Pitesti
2024
Special Olympics
2024
Universitatea Națională de Știință și Tehnologie Politehnica București
2024
University of Wisconsin–Madison
2014-2019
Nearly all adults with Down syndrome show neuropathology of Alzheimer's disease, including amyloid-β deposition, by their fifth decade life. In the current study, we examined association between brain assessed via in vivo assessments neocortical Pittsburgh compound B, and scores on an extensive neuropsychological battery measures cognitive functioning 63 (31 male, 32 female) aged 30–53 years who did not exhibit symptoms dementia. Twenty-two were identified as having elevated B retention...
Abstract Introduction In Down syndrome (DS), the overproduction of amyloid precursor protein is hypothesized to predispose young adults early expression Alzheimer‐like neuropathology. Methods PET imaging with carbon 11–labeled Pittsburgh compound B examined pattern amyloid‐β deposition in 68 nondemented DS (30–53 years) determine relationship between and normal aging. Standard uptake value ratio (SUVR) images were created cerebellar gray matter as reference region. Results Multiple linear...
Couples who have a child or adolescent with autism spectrum disorder (ASD) are faced the difficult decision of how to divide childcare responsibilities and paid employment. We examined division labor its relation parenting stress marital adjustment in 73 married couples ASD. Mothers fathers independently reported on their global level then completed 7-day online daily diary time spent childcare, employment, satisfaction that one's spouse childcare. Overall, demonstrated pattern partial role...
Abstract Introduction Down syndrome (DS) arises from a triplication of chromosome 21, causing overproduction the amyloid precursor protein and predisposes individuals to early Alzheimer's disease (AD). Methods Fifty‐two nondemented adults with DS underwent two cycles carbon 11‐labeled Pittsburgh compound B ([ 11 C]PiB) T1 weighted magnetic resonance imaging (MRI) scans 3.0 ± 0.6 years apart. Standard uptake value ratio (SUVR) images (50–70 minutes; cerebellar gray matter [GM]) GM volumes...
Despite the prevalence of depressive disorders among youth, there is no health system model to address prevention these disorders. With goal creating effective, tolerable, and scalable interventions for adolescent depression, we have fielded three randomized clinical trials, centered in care delivery organizations that use a whole-of-society approach: (a) Path 2 Purpose (N = 664), comparing Competent Adulthood Transition with Cognitive Behavioral, Humanistic, Interpersonal Training...
Participatory action research methodologies may empower and protect marginalized individuals; however, they remain underutilized. Limited studies have investigated the impact of participatory research, specifically on individuals with intellectual disability (ID). This study examines (1) perspectives co-researchers ID their involvement in process (2) feasibility inclusion based staff (academic faculty graduate students without ID). Three were interviewed regarding participation. Thematic...
This study explored the impact of parental sleep quality on experience behavior problems by children with autism spectrum disorder. A 14-day daily diary was used in a sample 176 mother–father couples. Dyadic multilevel models were conducted to examine between-person and within-person effects previous-night parents’ rating level child disorder positive negative affect. Results indicated that persistently poor associated differences initial for mothers. At level, moderated association between...
There is a paucity of research on psychosocial treatments for depression in adults with intellectual disability (ID). In this pilot study, we explored the efficacy group CBT treatment that involved caregiver component mild ID depressive disorder.Sixteen and disorder participated 10-week 8 served as usual (TAU) control group. Adults caregivers completed measures symptoms, behavior problems, social skills at pre-treatment, post-treatment, 3-month follow-up. also series tasks to measure their...
Leisure activity has been linked to optimal ageing outcomes, yet little is known about the type and level of leisure adults with Down syndrome currently engage in, factors that promote hinder their activities.A daily diary was utilized provide an in-depth description average 44 (aged 25-56 years) across a typical 7-day period. Factors related participation, including initiators, social partners, settings barriers, were examined.Findings indicated majority did not meet established physical...
To build capacity among people with intellectual and developmental disabilities to become co-researchers they need the opportunity learn about research.
Background:The Down syndrome (DS) population is genetically predisposed to amyloid-β protein precursor overproduction and Alzheimer's disease (AD). Objective:The temporal ordering spatial association between amyloid-β, glucose metabolism, gray matter (GM) volume in the DS can pro vide insight into those associations more common sporadic AD. Methods:Twenty-four adults (13 male, 11 female; 39±7 years) with underwent [11C]PiB, [18F]FDG, volumetric MRI scans. Voxel-wise PiB SUVR, FDG GM were...
The present study examined leisure activity and its association with caregiver involvement (i.e., residence time spent primary caregiver) in 62 middle-aged older adults Down syndrome (aged 30-53 years). Findings indicated that frequently participated social passive activities, low participation physical mentally stimulating activities. Residence were associated activity. findings suggest a need for support services aimed at increasing opportunities participating by syndrome. These should...
The present study provided an investigation of associations between leisure activity and early Alzheimer's disease neuropathology (i.e., brain β-amyloid) episodic memory in a sample 65 adults with Down syndrome (aged 30-53 years), at baseline follow-up, approximately three years apart. Findings indicated that was not associated β-amyloid or change from to follow-up. Greater cognitively stimulating better baseline, greater social less decline High (as opposed low) levels overall moderated the...
The paper aims to determine the relation of indices lower limbs strength in 12-13-year-old soccer players. Methods. Therefore, exploratory research was conducted within CS Otopeni, department, with a group 26 children aged 12-13 years. tested by means Opto Jump Next system. Specific tests used: Test 1, CMJ (flight time and height), test 2, Squat jumps (SJ) time, height) 3, Jumps 15 sec (number jumps, contact flight power, pace RSI). between measured analyzed using Pearson correlation...
By carefully watching the handball games both in domestic championship and from World European Championships, we come to conclusion that great performances are only achieved by teams have a very good physical training, so implicitly general specific motor ability excellently doubled preparation on training factors: technical, theoretical, tactical psychological. The choice of plyometric exercises must imitate skills, maximize strengthening muscles trigger movement and, certain cases,...
The present study examined the association between adverse childhood experiences (ACEs) and body mass index (BMI) status among children youth with special health care needs (CYSHCN), role of characteristics lifestyle factors in predicting BMI. Data from 2016–2020 National Survey Children's Health were utilized. Key variables included: ACEs, BMI status, level functional impairment, depression, weekly physical activity, daily screen time. Multivariable ordinal logistic regression analyses used...
In Down syndrome (DS), the overproduction of amyloid precursor protein gene results in increased β-amyloid accumulation and consequently, an risk for early Alzheimer's disease (AD). Individuals with DS also have prevalence disordered sleep. Poor sleep has been associated AD-related pathology cognitive impairment general population; however, relationship between accumulation, cognition population remains unknown. As a part ongoing Neurodegeneration Aging Syndrome (NiAD) project, forty-eight...