A5059982336- Amoebic Infections and Treatments
- Parasitic Infections and Diagnostics
- Heme Oxygenase-1 and Carbon Monoxide
- Immunotherapy and Immune Responses
- SARS-CoV-2 and COVID-19 Research
- Neonatal Health and Biochemistry
- Pediatric Hepatobiliary Diseases and Treatments
- Hedgehog Signaling Pathway Studies
- Evolution and Paleontology Studies
- Animal Virus Infections Studies
- Pluripotent Stem Cells Research
- Bone and Joint Diseases
- Rabbits: Nutrition, Reproduction, Health
- Primate Behavior and Ecology
- 3D Printing in Biomedical Research
- Cancer Cells and Metastasis
- Pancreatitis Pathology and Treatment
- Peroxisome Proliferator-Activated Receptors
- Legionella and Acanthamoeba research
- Infectious Diseases and Tuberculosis
Center for Research and Advanced Studies of the National Polytechnic Institute
2020-2024
Instituto Politécnico Nacional
2018-2024
Centro de Investigación en Materiales Avanzados
2022
Universidad Nacional Autónoma de México
2015
Three-dimensional cultures are powerful tools to recapitulate animal and human tissues. Under the influence of specific growth factors, adult stem cells differentiate organize into 3D named organoids. The molecular phenotyping these structures is an essential step for validating organoid model. However, limited number organoids generated in culture yields very low amounts genetic material, making difficult. Recently, digital PCR (dPCR) techniques have become available highly sensitive...
From August 2011 to November 2013, 68 opossums (8 Didelphis sp., 40 virginiana, 15 marsupialis, and 5 Philander opossum) were collected in 18 localities from 12 Mexican states. A total of 12,188 helminths representing 21 taxa identified (6 trematodes, 2 cestodes, 3 acanthocephalans 10 nematodes). Sixty-six new locality records, 9 host one species, the trematode Brachylaima didelphus, is added composition helminth fauna Mexico. These data, conjunction with previous bring number parasitizing...
The Receptor-Binding Domain (RBD) of the Spike (S) protein from Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has glycosylation sites which can limit production reliable antigens expressed in prokaryotic platforms, due to glycan-mediated evasion host immune response. However, regions without glycosylated residues capable inducing neutralizing antibodies could be useful for antigen systems that do not carry machinery. To test this hypothesis, potential NG06 and NG19, located...
Early steps of tissue invasion by Entamoeba histolytica are mediated adhesion and migration through matrix components such as fibronectin with the participation actin cytoskeleton. Striking differences in their produced structures, movement, were found. These observations suggest differential changes ability to organize cytoskeleton and, therefore, modify its morphology after fibronectin. To understand these observations, we explore deeper pathway E. compared dispar, analyzing activation...
Human amoebiasis still represents a major health problem worldwide. Metronidazole has been used as the most common drug to treat disease; however, it is also known that causes undesirable side effects. This led search for new pharmacological alternatives which include phytochemical compounds with antiamoebic We analyzed amoebicidal activity of stevioside (STV), diterpene glycoside present in Stevia rebaudiana, on trophozoites E. histolytica. Different concentrations STV were tested, and an...
The development of amoebic liver abscess (ALA) leads to necrosis, accompanied by an exacerbated inflammatory response and the formation multiple granulomas. Adequate management infection through administration treatment timely organ damage allows injury heal with optimal regeneration without leaving scar tissue, which does not occur in other types such as viral hepatitis that may conducts fibrosis or cirrhosis. Hedgehog signaling pathway (Hh) is crucial embryonic stage, while adults it...
Abstract Highly dynamic ribosomes, glycogen granules, thinly fibrillar material, and multiple membrane‐bound vesicles are embedded in the matrix‐rich cytoplasm of Entamoeba spp. trophozoites. The absence a Golgi apparatus these amoebae has been commonly accepted. Here we challenge this observation by incubating histolytica dispar with monensin, an ionophore that produces swelling apparatus. We observe changes trophozoites through standard transmission electron microscopy, cryofixation...