- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Medicinal Plant Extracts Effects
- Peripheral Neuropathies and Disorders
- Peripheral Artery Disease Management
- IgG4-Related and Inflammatory Diseases
- Neurological Disease Mechanisms and Treatments
- Neurological Disorders and Treatments
- Mycobacterium research and diagnosis
- Pharmacological Receptor Mechanisms and Effects
- Simulation-Based Education in Healthcare
- Vasculitis and related conditions
- Dysphagia Assessment and Management
- Stroke Rehabilitation and Recovery
- Esophageal and GI Pathology
- Cancer Immunotherapy and Biomarkers
- Innovations in Medical Education
- Autoimmune Neurological Disorders and Treatments
- Clinical Nutrition and Gastroenterology
- Migraine and Headache Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Tuberculosis Research and Epidemiology
- Brain Metastases and Treatment
- Hallucinations in medical conditions
- Diagnosis and treatment of tuberculosis
University of Cincinnati
2021-2025
University of Cincinnati Medical Center
2021-2025
Rocky Vista University
2017
Introduction: Acute treatment for stroke often requires emergent interhospital transfer access to advanced therapies not available at the initial hospital. Prolonged times have been associated with worse outcomes. Door-in-door-out time (DIDO: amount of a patient spends in transferring emergency department [ED]) is an important quality metric acute care, current recommendations DIDO ≤ 120 minutes. We sought characterize trends and predictors transfers using Greater Cincinnati Northern...
Background: Understanding the trends of stroke incidence and how those strokes are distributed across race is a critical step to implement trials programs decrease burden caused by nationally. In 2015, we reported that decreasing in both Black White adults. We investigated continued 2020. Methods: this population-based surveillance study, all cases within 5-county population surrounding Cincinnati adults aged ≥20 years were ascertained during full year every 5 from 1993 Cases abstracted...
Introduction: ICD-10 codes are often used for stroke research in administrative databases. Few studies have assessed their reliability large, representative populations of the United States. We validated a large population-based study Greater Cincinnati/Northern Kentucky (GCNK) region. Methods: ascertained all acute strokes GCNK region during 2020 using methodology. All hospitalizations were screened comprehensive list ICD any diagnosis position (G45-46/H34/I60-69). Additional cases captured...
Background: Black individuals are at a higher risk of stroke, but little is known about racial disparities in functional outcome. Using representative population-based study, we examined outcome over multiple timepoints the first year after acute ischemic stroke (AIS). Methods: We ascertained all hospitalized AIS events Greater Cincinnati Northern Kentucky region from July 2019-December 2020 (Black individuals) and January 2020-December (White individuals). Potential cases were identified by...
Background: Prior literature has reported patterns of racial differences in percutaneous endoscopic gastrostomy (PEG) placement for patients with post-stroke dysphagia. Reasons this disproportion are not well understood, but critical clinical decision making. Long-term implications PEG considerable, given complication rates and that reducing oral intake can significantly impact recovery swallow function. In population-based study, we evaluated the influence patient-related factors stroke...
Background: Ongoing surveillance of stroke incidence over time by demographic groups is critical to understand trends in disease burden and effective interventions. Our objective was examine changes sex age 27 years. Methods: In a population-based study covering 5-county region southern Ohio northern Kentucky, hospital cases were ascertained adjudicated trained physicians during six 1-year periods (07/1993–06/1994, 1999, 2005, 2010, 2015, 2020). Temporal evaluated sex, age, subtype (ischemic...
Introduction: Time from stroke symptom onset to emergency department (ED) arrival (OTA) is an important driver of acute functional outcomes and mortality for both ischemic (AIS) intracerebral hemorrhage (ICH). Acute therapies AIS are time-sensitive, there several recently published time-dependent therapeutic trials ICH, yet little known about the patterns ED presentation over time. We sought analyze trends predictors times ICH within Greater Cincinnati/Northern Kentucky Stroke Study....
Background: Large vessel occlusion (LVO) is associated with high morbidity and mortality but has had major advances in treatment options. Prior studies the United States have been limited by referral bias. We sought to study population-based prevalence, presenting features, management, of LVO stroke. Methods: From Greater Cincinnati/Northern Kentucky Stroke Study (GCNKSS), we selected patients a diagnosis acute ischemic stroke (AIS) using ICD-10 codes adults ≥18 years age symptomatic...
Idiopathic hypertrophic pachymeningitis (IHP) is a rare, chronic inflammatory disorder characterized by fibrotic thickening of the dura mater. The etiology IHP currently unknown; however, often mimics other conditions (causes secondary pachymeningitis) including neurosarcoidosis, granulomatosis with polyangiitis (GPA), and IgG4-related disease. manifests clinically spectrum neurologic symptoms, headache, paresthesia, cranial nerve (CN) palsies, seizures. Here, we discuss diagnosis management...
ABSTRACT. Tuberculosis (TB) can cause significant morbidity and mortality among solid organ transplant (SOT) recipients, including disseminated disease. Most TB cases after SOT occur in kidney although data about this population are sparse. may present atypically immunocompromised patients, underscoring why physicians must maintain high clinical suspicion when pertinent epidemiological risk factors present, birth or former residence a country with endemic TB. We describe unique case of...
To evaluate the frequency of neurological-immune-related adverse events (n-irAES) and associated demographic/clinical characteristics oncological patients treated with immune-checkpoint inhibitors (ICIs) at University Cincinnati (UC).
Background: Retinal artery occlusion (RAO) is a stroke equivalent that causes significant morbidity. There has been growing emphasis on urgent in-hospital evaluation of these patients, both to facilitate potential thrombolytic therapy and expedite workup; however, little known regarding its effect systems care. We thus examined presenting characteristics management hospitalized RAO patients using the Greater Cincinnati Northern Kentucky Stroke Study (GCNKSS). Methods: The GCNKSS...