- Occupational exposure and asthma
- Occupational Health and Safety Research
- Indoor Air Quality and Microbial Exposure
- Air Quality and Health Impacts
- Occupational and environmental lung diseases
- Inhalation and Respiratory Drug Delivery
- Contact Dermatitis and Allergies
- Hip and Femur Fractures
- Bone fractures and treatments
- Orthopedic Surgery and Rehabilitation
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Facilities and Workplace Management
- Foot and Ankle Surgery
- Asthma and respiratory diseases
- Quality and Safety in Healthcare
- Noise Effects and Management
- Infection Control and Ventilation
- Mycobacterium research and diagnosis
- Mining Techniques and Economics
- Pelvic and Acetabular Injuries
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Trauma and Emergency Care Studies
- Bone health and osteoporosis research
- Building Energy and Comfort Optimization
- Chemical Safety and Risk Management
Royal Sussex County Hospital
2017-2024
University Hospitals Sussex NHS Foundation Trust
2024
NIHR Surgical Reconstruction and Microbiology Research Centre
2009-2023
Heartlands Hospital
2011-2022
University Hospitals Birmingham NHS Foundation Trust
2018-2021
Queen Elizabeth Hospital Birmingham
2021
East Sussex Healthcare NHS Trust
2020-2021
Conquest Hospital
2020
University of Birmingham
1985-2019
Heart of England NHS Foundation Trust
2011-2018
A cross sectional survey investigating "building sickness" was carried out in two buildings with similar populations of office workers but differing ventilation systems, one being fully air conditioned humidification and the other naturally ventilated. The prevalence symptoms related to work assessed by a questionnaire administered doctor. stratified, randomly selected sample seen (84% response). Building sickness includes several distinct syndromes work, most which were significantly more...
Exposure to chromium during electroplating is a recognised though poorly characterised cause of occupational asthma. The first series such patients referred specialist lung disease clinic reported.The diagnosis asthma was made from history with rest day improvement and confirmed by specific bronchial provocation testing potassium dichromate nickel chloride.Seven workers had been exposed chrome fumes for eight months six years before developed. One subject, although 11 without symptoms,...
To study the health, employment, and financial outcome of occupational asthma.A follow workers with confirmed specialist lung disease clinic.All had a diagnosis asthma made at least one year earlier. Diagnosis was by serial peak expiratory flow measurement, specific bronchial provocation testing, or immunology.Respiratory symptoms, medication, pulmonary function, employment state, position.112 total 140 eligible were followed up. 32% patients remained exposed to causative agent. These more...
There has been a growing awareness of the importance dermal exposure in recent years. A wide range techniques are employed to measure exposure, which surrogate skin such as patch sampling and whole body frequently used. One problems associated with is that different methods often produce results due differences principles involved sample collection. As consequence little progress towards establishing limits made. Both patches clothing act passive samplers intended collect all substance...
Acute irritant exposures at work are well-recognized causes of asthma. In the occupational setting, low-dose exposure to same agent does not provoke Occupational asthma (OA) with latency due irritants is widely accepted.To compare workers OA likely be more usual sensitization-induced OA.Following identification a worker who fulfils all criteria for irritant-induced whose investigation documented lime dust as cause his OA, we searched Shield reporting scheme database between 1989 and 2010...
The British Thoracic Society (BTS) Standards of Care (SoC) Committee produced a standard care for occupational asthma (OA) in 2008, based on systematic evidence review performed 2004 by the Occupational Health Research Foundation (BOHRF).BOHRF updated base from 2004-2009 2010.This article summarises changes and is aimed at physicians, nurses other healthcare professionals primary secondary care, health public employers, workers their health, safety representatives.Various recommendations...
Office lighting has been suggested as one of the possible factors in producing 'building sickness'. Health questionnaires were completed by 106 out 109 (97%) workers six randomly sampled multi-occupied offices each two buildings, air-conditioned and naturally ventilated. There was a significantly higher prevalence work-related headache lethargy building than ventilated one. also less daylight lower mean luminance illuminance work positions despite there being more lights on (p 0.01). The had...
<h3>Background:</h3> The diagnosis of occupational asthma requires objective confirmation. Analysis serial measurements peak expiratory flow (PEF) is usually the most convenient first step in diagnostic process. A new method analysis originally developed to detect late asthmatic reactions following specific inhalation testing described. This was applied PEF made over many days workplace supplement existing methods analysis. <h3>Methods:</h3> 236 records from workers with independently...
Funnel plots are an increasingly common graphical tool which widely used in the literature. They were first introduced by Light and Pillemer 1984 . In scientific literature, funnel to identify probability of bias meta-analyses compare institutional performance. The ability variation is better with than tabular display. addition, way data presented can directly influence interpretation results. This was demonstrated Marshall et al (2004) , who mortality both a league table control chart...
Background This study used data from a large UK outbreak investigation, to develop and validate new case definition for hypersensitivity pneumonitis due metalworking fluid exposure (MWF‐HP). Methods The clinical all workers with suspected MWF‐HP were reviewed by an experienced panel of clinicians. A Score was then developed match the “gold standard” opinion as closely possible, using standard diagnostic criteria that relatively weighted their positive predictive value. Results reproducible,...
OBJECTIVES: To describe the radiographic changes in coalworkers exposed to unusual concentrations of respirable quartz during 1970s, and relate these exposure measurements. METHODS: Men who had worked at one Scottish colliery 1970s were invited a health survey. Chest radiographs taken from 547 subjects. Classifications films under International Labour Organisation (ILO) 1980 scheme related, by logistic regression, existing data on individual men's exposures dust quartz. RESULTS: Taking...
Introduction The COVID-19 pandemic presented extraordinary challenges to the UK healthcare system. This study aimed assess impact of lockdown on epidemiology, treatment pathways and 30-day mortality rates hip fractures. Outcomes positive patients were compared against those who tested negative. Methods An observational, retrospective, multicentre was conducted across six hospitals in South East England. Data retrieved from National Hip Fracture Database electronic medical records. collected...
Cleaning agents are now a common cause of occupational asthma (OA) worldwide. Irritant airway and sensitization mechanisms implicated for variety old new agents.To describe the exposures responsible cleaning agent OA diagnosed within UK specialist lung disease service between 2000 2016.The Birmingham NHS Occupational Lung Disease Service clinical database was searched cases caused by agents, data were gathered on age, gender, atopic status, smoking history, symptom onset, diagnostic...
Healthcare practice in the UK has moved away from using aldehyde disinfectants for decontamination of endoscopes, part due to risk respiratory sensitization. Peracetic acid (PAA) combination with hydrogen peroxide (HP) is a commonly used alternative.We describe case occupational asthma (OA) diagnosed at our specialist lung disease clinic and caused by exposure PAA-HP mixture, as disinfectant an endoscope washer-disinfector machine.A 48-year-old man employed mycologist environmental...