A5087640878- Gastroesophageal reflux and treatments
- Gastric Cancer Management and Outcomes
- Immunodeficiency and Autoimmune Disorders
- Colorectal Cancer Screening and Detection
- Liver Disease Diagnosis and Treatment
- Gastrointestinal motility and disorders
- Eosinophilic Esophagitis
- Inflammatory Bowel Disease
- Intestinal and Peritoneal Adhesions
- Liver Disease and Transplantation
- Helicobacter pylori-related gastroenterology studies
- Aortic Thrombus and Embolism
- Esophageal Cancer Research and Treatment
- Abdominal vascular conditions and treatments
- Esophageal and GI Pathology
- Renal and Vascular Pathologies
- Hepatocellular Carcinoma Treatment and Prognosis
Meditest
2015
University of Szczecin
2009
Abstract Background Tumor necrosis factor-like cytokine 1A (TL1A) is an upstream regulator of pro-inflammatory cytokines and fibrosis signals. PRA023 anti-TL1A monoclonal antibody in development for multiple inflammatory/fibrotic diseases using a precision medicine approach with companion diagnostic (CDx). This Phase 2 placebo-controlled, multi-center, double-blind study aimed to assess the efficacy safety induction treatment adults moderately severely active ulcerative colitis (UC). Methods...
Abstract Background Randomized trials have confirmed the efficacy of prucalopride for treatment chronic constipation up to 12 weeks. This study aimed assess over a 24‐week period (ClinicalTrials.gov: NCT01424228). Methods Adults with and ≤2 spontaneous complete bowel movements ( SCBM s)/week were randomized receive 2 mg or placebo daily 24 The primary endpoint was proportion patients achieving mean ≥3 s/week period, assessed using e‐diaries. Secondary outcomes safety parameters throughout...
The proper visibility of mucosa during esophagogastroduodenoscopy (EGD) is crucial for the detection early upper gastrointestinal tract lesions. In contrast to colonoscopy, no validated scoring system assessment mucosal cleanliness has been developed so far. aim study was create and validate standardized grading (POLPREP) assess EGD.To EGD, 4-point scale (0-3). Twelve operators assessed 18 images esophagus, stomach, duodenum twice (in 2 weeks interval). validation round, endoscopy reports...
Endoscopic ultrasound (EUS) permits identification of dilated veins the intrinsic rectal venous system (deep varices) in portal hypertension. The aim this cross-sectional study was to assess prevalence of, and risk factors for, deep varices, using EUS.A cohort 96 patients with cirrhosis studied. Both routine rectoscopy EUS were performed. Deep varices assessed as peri-rectal para-rectal. A three-grade scale used size varices.On rectoscopic examination, congestive rectopathy seen 11(11%)...
EsoCap is a thin mucoadhesive film designed to target the oesophageal mucosa. The device loaded with mometasone furoate (ESO-101) under investigation for treatment of eosinophilic oesophagitis (EoE).
A 62-year-old male presented with mild dysphagia and upper abdominal discomfort. He underwent gastrointestinal endoscopy, which was described as showing “unusual- looking” oesophageal varices. …