A5029725271- MRI in cancer diagnosis
- Renal cell carcinoma treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Neuroendocrine Tumor Research Advances
- Renal and Vascular Pathologies
- Lung Cancer Research Studies
- Neuroblastoma Research and Treatments
- Pediatric Urology and Nephrology Studies
- Radiomics and Machine Learning in Medical Imaging
- Liver Disease Diagnosis and Treatment
- Renal and related cancers
- Advanced X-ray and CT Imaging
- Aortic aneurysm repair treatments
- Liver Disease and Transplantation
- Pancreatic and Hepatic Oncology Research
- Ultrasound and Hyperthermia Applications
- Radiation Dose and Imaging
- Medical Imaging and Pathology Studies
- Radiopharmaceutical Chemistry and Applications
- Lung Cancer Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Medical Imaging Techniques and Applications
- Congenital Anomalies and Fetal Surgery
- Urological Disorders and Treatments
- Prostate Cancer Treatment and Research
Ludwig-Maximilians-Universität München
2016-2025
LMU Klinikum
2017-2025
European Neuroendocrine Tumor Society
2021-2024
München Klinik
2018-2022
Baylor College of Medicine
2020
University of Alabama at Birmingham
2020
Thomas Jefferson University
2020
University Radiology
2020
Northeast Ohio Medical University
2020
University of Atlanta
2020
Purpose: The aim of the present retrospective single-center study is to evaluate diagnostic performance contrast-enhanced ultrasound (CEUS) in evaluation renal oncocytoma.Method: Thirteen patients with histopathologically confirmed oncocytoma and 26 cell carcinoma were included this on whom CEUS was performed between 2005 2015. applied contrast agent a second-generation blood pool agent. examinations interpreted by single radiologist more than 15 years experience (EFSUMB Level 3).Results:...
Background: Metastatic castration-resistant prostate cancer poses a therapeutic challenge with poor prognosis. The VISION trial showed prolonged progression-free and overall survival in patients treated lutetium Lu 177 vipivotide tetraxetan ( Lu-PSMA-617) radioligand therapy compared using the standard of care (SoC) alone. objective this study was to determine cost-effectiveness Lu-PSMA-617 treatment SoC therapy. Methods: A partitioned model developed data from trial, which included regimens...
Ultrasound is an essential imaging tool for evaluating physiological and pathological fetal or maternal conditions during pregnancy. Published data limited with respect to the application of CEUS has already been safely applied assessing uteroplacental blood flow, cesarean scar pregnancy invasive placenta percreta. CT MRI scans must be thoroughly evaluated due harmful ionizing radiation cerebral gadolinium deposition, respectively. The aim present retrospective single-center study assess...
Background and Purpose: Basilar artery occlusion is associated with high morbidity mortality. Optimal imaging treatment strategy are still controversial prognosis estimation challenging. We, therefore, aimed to determine the predictive value of computed tomography perfusion (CTP) parameters for functional outcome in patients basilar context endovascular treatment. Methods: Patients who underwent were selected from a prospectively acquired cohort. Ischemic changes assessed...
Abstract Our retrospective single-center study aims to evaluate the impact of structured reporting (SR) using a self-developed template on report quality compared free-text (FTR) in [ 18 F]SiTATE Positron Emission Tomography/Computer Tomography (PET/CT) for primary staging and therapy monitoring patients diagnosed with neuroendocrine tumors (NET). In total 50 were included. FTRs SRs generated post-examination. All reports evaluated by radiologist surgeon through questionnaire determine their...
Targeted alpha therapy (TAT) with 225Ac has shown promising results in metastatic castration-resistant prostate cancer (mCRPC) patients pre-treated [177Lu]Lu-PSMA radioligand (RLT). A combination treatment regimen adding 177Lu to decreased activities may improve toxicity profile while maintaining sufficient anti-tumor effect. We therefore evaluated clinical and image-based response parameters treated 225Ac-/177Lu-PSMA therapies (ALCT). Complete (RECIP-CR), partial (RECIP-PR), stable disease...
Background/Objectives: Peptide Receptor Radionuclide Therapy (PRRT) is approved for patients with inoperable, progressive and/or metastatic well-differentiated NETs. Before the approval of Lutathera®, locally manufactured 177Lu-HA-DOTATATE was used on a regular basis in clinical routine. The aim this study (1) to compare hematotoxicity Lutathera® GEP-NET and (2) recommended treatment interval 8 weeks between each cycle prolonged scheme up 11 both Lutathera®. Methods: included GEP NETs (n =...
To compare the sensitivity and specificity of contrast-enhanced ultrasound (CEUS) magnetic resonance imaging (MRI) in evaluation unclear renal lesions to histopathological outcome.A total 36 patients with a single solid lesion initial studies between 2005 2015 were included. CEUS MRI used for determining malignancy or benignancy findings correlated outcome. Out masses 28 malignant (77.8%) 8 found be benign (22.2%). Diagnostic accuracy was testes by using diagnosis as gold standard.CEUS...
Radiolabelled somatostatin analogues targeting receptors (SSR) are well established for combined positron emission tomography/computer tomography (PET/CT) imaging of neuroendocrine tumours (NET). [18F]SiTATE has recently been introduced showing high image quality, promising clinical performance and improved logistics compared to the reference standard 68Ga-DOTA-TOC. Here we present first dosimetry optimal scan time analysis.Eight NET patients received a [18F]SiTATE-PET/CT (250 ± 66 MBq) with...
Background: Digital breast tomosynthesis (DBT) and abbreviated MRI (AB-MRI) offer superior diagnostic performance compared to conventional mammography in screening women with intermediate risk of cancer due dense tissue. The aim this model-based economic evaluation was analyze whether AB-MRI is cost-effective cohort DBT. Methods: Decision analysis Markov simulations were used model the cumulative costs quality-adjusted life-years (QALYs) over a time horizon 30 years. Model input parameters...
Background: Colorectal cancer is among the most prevalent entities worldwide, with every second patient developing liver metastases during their illness. For local treatment of metastases, a surgical approach as well ablative options, such microwave ablation (MWA) and radiofrequency (RFA), are available. The aim this study to evaluate cost-effectiveness RFA, MWA surgery in oligometastatic colorectal (omCRC) that amenable for all investigated modalities. Methods: A decision analysis based on...
Abbreviated breast MRI (AB-MRI) was introduced to reduce both examination and image reading times improve cost-effectiveness of cancer screening. The aim this model-based economic study analyze the full protocol (FB-MRI) vs. AB-MRI in screening women with dense tissue for cancer.Decision analysis a Markov model were designed cumulative costs effects biennial terms quality-adjusted life years (QALYs) from US healthcare system perspective. Model input parameters cohort adopted recent...
Abstract Objective This study analyzes the potential cost-effectiveness of integrating an artificial intelligence (AI)–assisted system into differentiation incidental renal lesions as benign or malignant on MR images during follow-up. Materials and methods For estimation quality-adjusted life years (QALYs) lifetime costs, a decision model was created, including MRI strategy + AI strategy. Model input parameters were derived from recent literature. Willingness to pay (WTP) set $100,000/QALY....
Contrast-enhanced-ultrasound (CEUS) has been frequently used in assessment of cystic renal lesions.The aim this study was to investigate the Bosniak classification CEUS compared CT and MRI a multi-center setting.Bosniak examinations lesions were imaging findings computed-tomography (ceCT) magnetic-resonance-imaging (ceMRI). Imaging results correlated histopathological reports. All performed by experts (EFSUMB level 3) using up-to-date examination-protocols.Overall, 173 subgroups (n = 87)...
Correct differentiation between malignant and benign incidentally found cystic renal lesions has critical implications for patient management. In several studies contrast-enhanced ultrasound (CEUS) showed higher sensitivity with respect to the accurate characterization of these compared MRI, but cost-effectiveness CEUS yet be investigated. The aim this study was analyze as an alternative imaging method MRI lesions. A decision model including diagnostic modalities created based on Markov...
Despite of the more potent immunosuppressive medication, vascular rejection is still a major issue after renal transplantation. Renal biopsy gold standard diagnostic to evaluate acute and chronic allograft rejection. As it an invasive there risk complications like haematoma, arteriovenous fistulas, active bleeding or infection. Contrast-enhanced ultrasound non-invasive imaging modality that allows visualising transplant perfusion.To analyse sensitivity specificity contrast-enhanced (CEUS)...