A5079018247- Classical Antiquity Studies
- Archaeology and Historical Studies
- Ancient Egypt and Archaeology
- Ancient Mediterranean Archaeology and History
- Acute Lymphoblastic Leukemia research
- Historical and Architectural Studies
- Childhood Cancer Survivors' Quality of Life
- Global Cancer Incidence and Screening
- Glioma Diagnosis and Treatment
- Byzantine Studies and History
- Historical, Religious, and Philosophical Studies
- Ancient Near East History
- Colonialism, slavery, and trade
- African history and culture analysis
- Classical Studies and Legal History
- Cutaneous Melanoma Detection and Management
- Lymphoma Diagnosis and Treatment
- Meningioma and schwannoma management
- Biblical Studies and Interpretation
- Neuroblastoma Research and Treatments
- Ancient and Medieval Archaeology Studies
- Historical and Religious Studies of Rome
- Sarcoma Diagnosis and Treatment
- RNA modifications and cancer
- Regional Development and Policy
University of London
2002-2021
University of Manchester
2008-2019
Royal Holloway University of London
2004-2017
Manchester Academic Health Science Centre
2011-2016
St Mary's Hospital
2016
Cancer Research UK
2003-2014
Cancer Research UK Manchester Institute
2011-2012
Universidad de Londres
1998-2010
Royal Manchester Children's Hospital
2000-2008
The Christie NHS Foundation Trust
2008
A new index and four graphical displays, termed “red–blue” plots, are presented to study measure clustering in spatially referenced count data. The can detect clusters the form of patches, comprising several nearby large counts, gaps, small counts. methods quantify degree which for each sample unit contributes towards overall clustering, either as part a patch or gap; provide tests nonrandomness clustering; facilitate comprehensive definition size dimension cluster. illustrated using aphid field
Cancer patients aged 15-24 years have distinct special needs. High quality cancer statistics are required for service planning. Data presented by primary site inappropriate this age group. We developed a morphology-based classification and applied it to national registration data England 1979-1997. The study included 25,000 cancers 134 million person-years at risk. Rates each diagnostic group age, sex time period (1979-83, 1984-87, 1988-92, 1993-1997) were calculated. Overall rates in 15-19...
Around 25% of all tumors in those 0–14 years age and 9% 15–24 involve the CNS. They are most common cause cancer-related deaths both groups. In adults 25–84 age, proportion CNS is 2%; 5-year overall survival 10%–15%; survivors have considerable morbidity. Comprehensive up-to-date population-based incidence data on these lacking. We present rates for primary based derived from high-quality national cancer registration system England. A total 54,336 malignant, benign, uncertain behavior were...
Abstract Background Langerhans cell histiocytosis (LCH) is a rare proliferative disorder of pathological cells, for which the aetiology and pathogenesis remain largely unknown. Procedure Information on 101 children with LCH registered population‐based Manchester Children's Tumour Registry (MCTR) between 1954 1998 was extracted from records MCTR. This included age, sex, date diagnosis, systems affected at diagnosis follow‐up. Results The overall incidence rate 2.6 cases per million child...
In a recent issue of this Journal, M. Alexander Speidel published new document concerning Roman military pay, receipt from Vindonissa dating to A.D. 38. This document, he claims, provides the missing link, which allows him present table pay rates for legionaries and auxiliaries Caesar Diocletian prove finally proposition resurrected by P. that soldiers auxiliary cohorts were paid five sixths annual legionaries. From re-examination texts documents traditionally used as evidence military, I...
Abstract BACKGROUND: It is believed that gonadal and extragonadal germ cell tumors (GCTs) arise from primordial cells may have similar etiopathogenesis. Unlike testicular GCTs, there has been limited comprehensive population‐based analysis of ovarian GCTs. METHODS: All malignant GCTs all central nervous system (CNS) with benign uncertain behavior were registered in England the age group 0 to 84 years 1979 2003 included current study. Incidence rates calculated adjusted world standard...
In England, cervical cancer is the second most common in women aged under 35 years. Overall incidence of has decreased since introduction national screening programme 1988 but recent trends young have not been studied detail. Information on 71 511 incident cases 1982–2006, 20–79-year-olds was extracted from a registration database. Changes were analysed by age group, time period and birth cohort. Poisson regression used to estimate annual percentage change (APC). incidence, during fell...
Cancer is the leading cause of disease-related death in teenagers and young adults aged 13-24 years (TYAs) England. We have analysed national 5-year relative survival among more than 30,000 incident cancer cases TYAs. For overall, improved from 63% 1979-84 to 74% during 1996-2001 (P<0.001). However, there were no sustained improvements over time high-grade brain tumours bone soft tissue sarcomas. Survival patterns varied by age group (13-16, 17-20, 21-24 years), sex diagnosis. leukaemia was...
Abstract Bone tumours comprise 0.2% of cancers overall but 5.7% in 15–24 year olds. To explore the relationship with adolescence we have analysed age‐incidence patterns bone a large national dataset. Data on incident cases 0–84 olds England, 1979–2003, were extracted from cancer registration data. Incidence rates per million person‐years by 5‐year age‐group, sex, morphology and primary site calculated adjusted to world standard population. Nine thousand one hundred forty‐six identified...
National melanoma incidence trends with details of anatomical site have not been previously described for England.To describe site-specific in cutaneous England as a whole during the last three decades.Anonymized data, 1979-2006, were obtained from national cancer registrations all patients up to age 89years incident primary invasive melanomas (n=124055). Sex-specific age-standardized rates and average annual percentage change calculated each broad site.Overall England, 81 100 per million,...
<h3>Background</h3> Neurofibromatosis Type 2 (NF2) is a dominantly inherited tumour syndrome with phenotype which includes bilateral vestibular (eighth cranial nerve) schwannomas. Conventional thinking suggests that these tumours originate at single point along the superior division of eighth nerve. <h3>Methods</h3> High resolution MRI was performed in children genetically proven to have NF2. The nerve (SVN) and inferior (IVN) were visualised their course points origin calculated as...