A5025536005- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Graphene and Nanomaterials Applications
- Blood properties and coagulation
- Photodynamic Therapy Research Studies
- Polymer Surface Interaction Studies
- Photoacoustic and Ultrasonic Imaging
- Heme Oxygenase-1 and Carbon Monoxide
- Nanoparticles: synthesis and applications
- Atmospheric chemistry and aerosols
- Quantum Dots Synthesis And Properties
- Pharmaceutical and Antibiotic Environmental Impacts
- Ultrasound and Hyperthermia Applications
- Air Quality and Health Impacts
- Antimicrobial Peptides and Activities
- Polymer composites and self-healing
- Noise Effects and Management
- Ultrasound and Cavitation Phenomena
- Photonic and Optical Devices
- Iron Metabolism and Disorders
- Advanced Polymer Synthesis and Characterization
- Carbon and Quantum Dots Applications
- Flame retardant materials and properties
- Bacterial biofilms and quorum sensing
Delft University of Technology
2022-2024
University of Turin
2017-2023
Inorganic materials are receiving significant interest in medicine given their usefulness for therapeutic applications such as targeted drug delivery, active pharmaceutical carriers and medical imaging. However, poor knowledge of the side effects related to use is an obstacle clinical translation. For development molecular drugs, concept safe-by-design has become efficient strategy with aim reducing costs, which can also accelerate translation into market. In case materials, application...
Transition metals play a key role in the pathogenic potential of urban particulate matter (PM). However, air quality regulations include exposure limits only for having known toxic like Pb, As, Cd, and Ni, neglecting other transition Fe Cu. Cu are mainly found water-soluble fraction PM. ions may persist strongly bound to particles, thus potentially acting as surface reactive sites. The contribution oxidative (OP) PM is likely different from that free since redox activity modulated by their...
Antimicrobial peptides (AMPs) are widely studied as therapeutic agents due to their broad-spectrum efficacy against infections. However, clinical use is hampered by the low in vivo bioavailability and systemic toxicity. Such limitations might be overcome using appropriate drug delivery systems. Here, preparation of a system (DDS) physical conjugation an arginine-rich peptide hydrothermal carbon nanoparticles (CNPs) has been explored, its antimicrobial Eschericia coli (E. coli) Staphylococcus...
Aim: To investigate near infrared-induced phototoxicity toward lung cancer cells, and the biodegradability effect on immune cells of glucose-derived carbon nanoparticles (CNPs). Methods: The human A549 adenocarcinoma cell line was used as a model to study CNPs. demonstrated in primary neutrophils macrophages. Results: Near infrared-activated CNPs elicited rapid death, characterized by elevation heat shock proteins induction DNA damage. were found be noncytotoxic macrophages susceptible...
Waterborne polyurethane (WPU) has attracted significant interest as a promising alternative to solvent-based (SPU) due its positive impact on safety and sustainability. However, limitations of WPU, such weaker mechanical strength, limit ability replace SPU. Triblock amphiphilic diols are materials enhance the performance WPU their well-defined hydrophobic-hydrophilic structures. Yet, our understanding relationship between arrangements triblock physical properties remains limited. In this...
Iron oxide nanoparticles (IONPs) have been largely investigated in a plethora of biological fields for their interesting physical-chemical properties, which make them suitable application cancer therapy, neuroscience, and imaging. Several encouraging results reported these contexts. However, the possible toxic effects some IONP formulations can limit applicability. In this work, IONPs were synthesized with carbon shell (IONP@C), providing enhanced stability both as colloidal dispersion...
Inorganic materials are receiving significant interest in medicine given their usefulness for therapeutic applications such as targeted drug delivery, carriers of active pharmaceutical and medical imaging. However, the poor knowledge side effects related to use is an obstacle clinical translation. For molecular development, safe-by-design has become a novel strategy that allows reduction costs acceleration translation research market. In case materials, application approaches hampered by how...
The paper first reviews the main laser based cancer therapies and then presents a new 9xx nm high power diode system specifically devised to irradiate carbon graphitic nanoparticles that have shown photodynamic photo-thermal behavior when exposed near-IR light. peculiarity of is its delivery through fiber probe integrates Bragg gratings allow monitoring induced temperature increase without introducing artifacts due interaction with beam. Experimental validations EPR spectrum measurements on...