Shu‐Yi Chen

ORCID: 0000-0002-6227-9081
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Research Areas
  • Polymer composites and self-healing
  • Peroxisome Proliferator-Activated Receptors
  • Advanced Polymer Synthesis and Characterization
  • Genomics, phytochemicals, and oxidative stress
  • Advanced Sensor and Energy Harvesting Materials
  • Flame retardant materials and properties
  • Dyeing and Modifying Textile Fibers
  • Marine and coastal ecosystems
  • Mineral Processing and Grinding
  • Connective tissue disorders research
  • Glycosylation and Glycoproteins Research
  • Escherichia coli research studies
  • Fuel Cells and Related Materials
  • Salmonella and Campylobacter epidemiology
  • Systemic Sclerosis and Related Diseases
  • Vitamin C and Antioxidants Research
  • Genetic factors in colorectal cancer
  • Insect Resistance and Genetics
  • Antimicrobial agents and applications
  • Polymer Nanocomposites and Properties
  • Surface Modification and Superhydrophobicity
  • Photopolymerization techniques and applications
  • Skin Protection and Aging
  • Invertebrate Immune Response Mechanisms
  • Coal Combustion and Slurry Processing

South China Agricultural University
2022-2024

National Taipei University of Technology
2019-2023

Delft University of Technology
2023

National Taiwan University of Science and Technology
2020

Tianjin Medical University
2017-2018

Jiangsu University
2017

First People's Hospital of Kunshan
2017

National Taiwan University
2002-2005

National United University
2005

Kaohsiung Medical University
2003

Endotoxin is a deadly pyrogen, rendering it crucial to monitor with high accuracy and efficiency. However, current endotoxin detection relies on multistep processes that are labor-intensive, time-consuming, unsustainable. Here, we report an aptamer-based biosensor for the real-time optical of endotoxin. The sensor exploits distance-dependent scattering gold nanoparticles (AuNPs) coupled nanofilm. This enabled by conformational changes endotoxin-specific aptamer upon target binding. can be...

10.1126/sciadv.adf5509 article EN cc-by-nc Science Advances 2023-02-08

Long non-coding RNAs (lncRNAs) are widely accepted as key players in various biological processes. However, the roles of lncRNA peripheral nerve regeneration remain completely unknown. Thus, this study, we performed microarray analysis to measure expression distal segment sciatic at 0, 3, 7 and 14 days following injury. We identified 5,354 lncRNAs that were differentially expressed: 3,788 expressed between 0 3; 3,314 7; 2,400 14. The results RT-qPCR two dysregulated consistent with those...

10.3892/ijmm.2017.2963 article EN cc-by-nc-nd International Journal of Molecular Medicine 2017-04-21

Introduction Alcoholic liver disease (ALD) is a global health problem for which there no current food and drug administration (FDA)-approved therapy. Oenothein B (OEB) macrocyclic dimer ellagic tannin that possesses abundant biological activities including antioxidant, anti-inflammation, antitumor, immunomodulatory, antimicrobial properties. Materials methods In this study, the hepatoprotective effect of OEB against ALD was investigated in vivo vitro . Results We found treatment dramatically...

10.3389/fnut.2022.1053718 article EN cc-by Frontiers in Nutrition 2022-12-12

Abstract As an environmental‐friendly coating material in industry, waterborne polyurethane–urea (WPU) is still not comparable with solvent‐based polyurethane (SPU) mechanical properties, due to the hydrophilic chain‐extender. Herein, a synthetic scheme increase abrasion resistance of WPU ether diol, and conventional chain‐extender (DMBA, 2,2‐bis[hydroxymethyl]butanoic acid) revealed. This study discuss degree micro‐phase separation (DPS) toughness, elongation, resistance, compared contain...

10.1002/app.50561 article EN Journal of Applied Polymer Science 2021-02-18

Waterborne polyurethane (WPU) has attracted significant interest as a promising alternative to solvent-based (SPU) due its positive impact on safety and sustainability. However, limitations of WPU, such weaker mechanical strength, limit ability replace SPU. Triblock amphiphilic diols are materials enhance the performance WPU their well-defined hydrophobic-hydrophilic structures. Yet, our understanding relationship between arrangements triblock physical properties remains limited. In this...

10.1021/acs.langmuir.3c00921 article EN cc-by Langmuir 2023-07-11

Treatment of carcinoma cell lines with 15-deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2), a natural ligand the peroxisome proliferator-activated receptor-γ, has been reported to induce apoptosis and/or inhibit proliferation. In this study, we investigated cytotoxic effect and action mechanisms 15d-PGJ2 in thyroid papillary cancer line, CG3. The results indicate that caused cytotoxicity increased amount intracellular reactive oxygen species (ROS) these cells. Mitochondrial oxidative phosphorylation...

10.1097/00001813-200208000-00011 article EN Anti-Cancer Drugs 2002-08-01

ABSTRACT: The penetration of sunlight into the water column plays a critical role in aquatic ecosystem. This study investigates light attenuation through Danshuei River estuary and explores models for quantifying it. measurement photosynthetically active radiation (PAR) indicates that conventional exponential with depth is very good model. A coefficient may be derived from PAR measurements at each location. simpler Secchi (SD) provide an approximate estimate coefficients inverse linear...

10.1111/j.1752-1688.2005.tb03746.x article EN JAWRA Journal of the American Water Resources Association 2005-04-01

ABSTRACT Due to increasing environmental concerns and depletion of petroleum resources, the use green materials has become popular with garment industry. In past, natural rubber, which is one most prevalent bio‐based elastomers, was used as waterproof coating for many applications due its inherent elasticity, high tear abrasion resistance, hydrophobicity. However, NR significant drawbacks when applying garments including poor adhesion polyester fabrics low breathability. Polyurethane, on...

10.1002/app.48002 article EN Journal of Applied Polymer Science 2019-06-02

To propose a green dyeing strategy permitting the incorporation of chromophores via promotion physical bonding and simple sewage processing procedure, for increasing reactivity conventional disperse dye, namely, 1-amino-4-hydroxy-2-phenoxyanthraquinone (Disperse Red 60, R60), to isocyanate groups miscibility with waterborne poly(urethane-urea) (WPU) was reported. The modified dye R60-OH prepared by alkylation 3-bromopropan-1-ol. Subsequently, reacted trifunctional (named R60-O-THDI), which...

10.1021/acsapm.2c02238 article EN ACS Applied Polymer Materials 2023-04-17

Abstract A breathable waterborne poly-(urethane/urea) (WPU) coating for textiles was synthesized by a pre-polymer method with 4,4′-Diisocyanate dicyclohexylmethane (H 12 MDI), Poly(propylene oxide)- b -poly(ethylene -poly(propylene oxide) triblock diols (PO-EO-PO diols), and Polyteramethylene glycol (PTMG). The PO-EO-PO were incorporated into the WPU to improve swelling issue of frequently observed in polyethylene (PEO) segments. stability, mechanical property, thermal properties,...

10.1088/2053-1591/abba50 article EN cc-by Materials Research Express 2020-09-21

Humic acid (HA), know to be ubiquitous in the natural environment, is present almost all soil, surface water, and plants. Earlier studies indicate that HA can affect thyroid economy via binding with iodide, inhibiting both peroxidase hepatic 5'-deiodinase rodents. However, effect of HA, a peroxisome proliferator rodents, on hormone receptor (TR) proliferator-activated (PPAR) human cells has not yet been examined. In this study, we demonstrate malic enzyme activity transcriptional activities...

10.1089/105072502760043422 article EN Thyroid 2002-05-01

This paper examines the impact of big data capability and value network reconstruction on digital business platforms ecosystem cocreation value. Furthermore, it presents a mechanism model, with model innovation as mediating variable. The findings this study are considerable importance for seeking to enhance their platform co-creation value, particularly in light reconstruction.

10.18686/frim.v2i6.4669 article EN Forum on research and innovation management. 2024-10-13

O-GlcNAcylation is a highly dynamic post-translational modification that plays key role in regulating phosphorylation of protein and cell survival. The proteins level regulated dynamically by O-GlcNAc transferase (OGT) β-N-acetylglucosaminidase (O-GlcNAcase, OGA). Although previous studies have suggested the neurodegenerative diseases, mechanism Alzheimer's disease (AD) remains unclear.The decrease alloxan, an OGT inhibitor, increase NAG-thiazolines (NAG-Ae), O-GlcNAcase inhibitor were...

10.5507/bp.2018.042 article EN cc-by Biomedical Papers 2018-09-05

In Taiwan, the numbers of elderly population and people with disabilities are rising. Accordingly, addressing accessible transportation needs these groups is an important issue. Currently, long-term care bus services in Taiwan provide on-demand point-to-point shuttle for elderly. However, currently unable to meet increasing market demand, resulting lower administrative efficiency unsatisfactory service quality. response, present study approaches challenge providing from a design perspective,...

10.21606/drs.2020.239 article EN cc-by-nc Proceedings of DRS 2020-09-10

Abstract The solvent‐free self‐healable waterborne poly(urethane‐urea) (SH‐WPU) product is environmentally friendly due to its lower volatile organic compounds emission during the coating process. This research revealed a strategy for breathable textile coating, that longer life of SH‐WPU coated fabric based on self‐healing dynamics triggered by disulfide bond rearrangement upon temperature elevation (e.g., ironing). was synthesized with 4,4′‐methylenebis cyclohexyl isocyanate as hard...

10.1002/app.52773 article EN Journal of Applied Polymer Science 2022-06-21

10.3980/j.issn.1672-5123.2017.9.32 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2017-09-01
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