A5049430915- Air Quality and Health Impacts
- Heavy Metal Exposure and Toxicity
- Liver Disease Diagnosis and Treatment
- Carcinogens and Genotoxicity Assessment
- Hepatitis C virus research
- Climate Change and Health Impacts
- Noise Effects and Management
- Hepatitis B Virus Studies
- Suicide and Self-Harm Studies
- Effects and risks of endocrine disrupting chemicals
- COVID-19 epidemiological studies
- Hearing, Cochlea, Tinnitus, Genetics
- Mosquito-borne diseases and control
- Energy and Environment Impacts
- Ocular Surface and Contact Lens
- Mental Health Treatment and Access
- Occupational exposure and asthma
- Infectious Diseases and Tuberculosis
- Pharmacological Effects and Assays
- Ocular Infections and Treatments
- Neuroscience and Neuropharmacology Research
- Hepatitis Viruses Studies and Epidemiology
- Global Health Care Issues
- Cervical Cancer and HPV Research
- Paraoxonase enzyme and polymorphisms
Cathay General Hospital
2025
Kaohsiung Medical University Chung-Ho Memorial Hospital
2011-2024
Kaohsiung Medical University
2012-2023
Ministry of Health and Welfare
1996-2020
Taipei City Government
2010-2016
Institute of Occupational Safety
2002-2014
University of Copenhagen
2012
National Taiwan University
2012
National Sun Yat-sen University
2012
National Taiwan University Hospital
2010
There is growing evidence with regard to the association between hepatitis C virus (HCV) infection and type 2 diabetes mellitus (T2DM). However, mutual link related virological implication have not been fully clarified. The impact of B (HBV) on epidemiological remains unclear. This study aimed elucidate T2DM viral infections, especially HCV infection. It also analyze associated characteristics implication.Cross-sectional analysis a computer-sampling survey among 10,975 participants (aged...
Objectives We evaluated the association between exposure to polycyclic aromatic hydrocarbons (PAHs) and immunological measurements using blood samples from coke oven workers exposed high low PAH levels. Methods A population-based cross-sectional study was conducted 2008–2009 with steel-rolling as control groups, respectively. Questionnaires on basic demographic information were administered. Personal breathing zone urine collected quantify personal intake biological response doses....
Hepatitis B virus (HBV) and hepatitis C (HCV) infections are major causes of liver disease in Taiwan have a great impact on the health this country. This study investigated seroprevalence HBV HCV southern Taiwan. Screening programs were performed from September 1999 to August 2005 for community-based surveillance disease. A total 28,797 adults Taiwan, including Kaohsiung City (n = 14,036), County 7,713), Pingtung 7,048) participated. The mean age was 50.3 ± 14.6 years (range, 20-97 years),...
The authors conducted a population-based, case-control study in Kaohsiung, southern Taiwan, Republic of China, to investigate the association between residential petrochemical exposure and leukemia risk among subjects 29 years age younger. Between November 1997 June 2003, 171 cases 410 controls matched for sex were recruited. Since assessment impacts depends on accurate estimates, developed procedure using geographic information system tools assign subjects' exposure. resulting...
Kaohsiung City, a modern metropolis of 1.5 million persons, has been the focus dengue virus activity in Taiwan for several decades. The aim this study was to provide temporal and spatial description epidemiology City by using data all laboratory-confirmed cases during 2003-2009. We investigated age- sex-dependent incidence rates spatiotemporal patterns confirmed through passive or active surveillance. Elderly persons were at particularly high risk virus-related sickness death. Of cases, ≈75%...
Background . This study tested the hypothesis that circulating microparticles (MPs) are useful biomarkers for predicting one-year mortality in patients with end-stage non-small cell lung cancer (ES-NSCLC). Methods and Results One hundred seven were prospectively enrolled into between April 2011 February 2012, each patient received regular follow-up after enrollment. Levels of four MPs circulation, (1) platelet-derived activated (PDAc-MPs), (2) apoptotic (PDAp-MPs), (3) endothelial-derived...
Abstract Sulfotransferase (SULT) 1A1 detoxifies and bioactivates a broad spectrum of substrates including xenobiotics. It has been suggested that the SULT1A1 his ( histidine ) allele, which is caused by for arg arginine substitution due to G→A transition at codon 213, carries significantly higher risk women develop breast cancer. We investigated association between / genotype esophageal cancer in men, 187 cases squamous cell carcinoma 308 controls from 3 medical centers Taiwan. Cigarette...
Lead exposure causes cardiac and vascular damage in experimental animals. However, there is considerable debate regarding the causal relationship between lead cardiovascular dysfunction humans. Paraoxonase 1 (PON1), a high-density lipoprotein-associated antioxidant enzyme, capable of hydrolyzing oxidized lipids thus protects against atherosclerosis. Previous studies have shown that several other metal ions are able to inhibit PON1 activity vitro. To investigate whether has influence on serum...
Abstract The carcinogenetic impact of risk factors on esophageal cancer (EC) may differ according to the portion esophagus where tumor occurs. It is unclear why more squamous cell carcinomas (SCC) developed in middle location. We carried out a multicenter case–control study Taiwan assess anatomical subsite discrepancy for this neoplasm regard consumption alcohol, tobacco and betel quid. Four hundred forty seven incident patients with pathology‐proven SCC (107 were upper‐third [U/3‐EC], 199...
The occurrence of out-of-hospital cardiac arrest (OHCA) is a critical life-threatening event which frequently warrants early defibrillation with an automated external defibrillator (AED). optimization allocating limited number AEDs in various types communities challenging. We aimed to propose two-stage modeling framework including spatial accessibility evaluation and priority ranking identify the highest gaps between demand supply for AEDs. In this study, total 6135 OHCA patients were...
Ambulance response times and resuscitation efforts are critical predictors of the survival rate after out-of-hospital cardiac arrests (OHCA). On other hand, rural-urban differences in OHCA rates an important public health issue.We retrospectively reviewed January 2011-December 2013 registry data Kaohsiung City, Taiwan. With particular focus on geospatial variables, we aimed to unveil risk factors predicting overall until hospital admission. Spatial analysis, network Kriging method by using...
OBJECTIVES: To investigate the relation of individual occupational exposure to total particulates benzene soluble fraction (BSF) ambient air with urinary 1-hydroxypyrene (1-OHP) concentrations among coke oven workers in Taiwan. METHODS: 80 and 50 referents were monitored individually for BSF breathing zone over three consecutive days. Exposures categorised as high, medium, or low based on situations. The high group (n = 18) worked oven. medium groups 41 n 21) at side > 4 hours < a day,...