Pei–Shih Chen

ORCID: 0000-0001-8377-499X
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About
Contact & Profiles
Research Areas
  • Air Quality and Health Impacts
  • Climate Change and Health Impacts
  • Indoor Air Quality and Microbial Exposure
  • Air Quality Monitoring and Forecasting
  • Burkholderia infections and melioidosis
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Global Health Care Issues
  • Influenza Virus Research Studies
  • Inhalation and Respiratory Drug Delivery
  • Infection Control and Ventilation
  • Energy and Environment Impacts
  • Viral Infections and Vectors
  • Complementary and Alternative Medicine Studies
  • Chemical Looping and Thermochemical Processes
  • ERP Systems Implementation and Impact
  • Toxic Organic Pollutants Impact
  • COVID-19 epidemiological studies
  • Catalysis for Biomass Conversion
  • Water Treatment and Disinfection
  • Viral gastroenteritis research and epidemiology
  • Animal Disease Management and Epidemiology
  • Asthma and respiratory diseases
  • Alcohol Consumption and Health Effects
  • Noise Effects and Management
  • Impact of Light on Environment and Health

Kaohsiung Medical University
2015-2025

Yulin University
2024

Kaohsiung Medical University Chung-Ho Memorial Hospital
2018-2023

Central Police University
2014-2023

National Sun Yat-sen University
2014-2023

Chang Gung University
2019

Chang Gung Memorial Hospital
2019

Mackay Memorial Hospital
2015

University of Bahrain
2011

Faculty of Public Health
2010

The spread of influenza and highly pathogenic avian (H5N1) presents a significant threat to human health. Avian outbreaks in downwind areas Asian dust storms (ADS) suggest that viruses might be transported by storms.We developed technique measure ambient viruses. We then used this concentrations these on ADS days background days, assess the relationships between viruses, air pollutants.A high-volume sampler was parallel with filter cassette evaluate spiked samples unspiked samples. Then,...

10.1289/ehp.0901782 article EN public-domain Environmental Health Perspectives 2010-04-30

This study was undertaken to determine whether there an association between fine particles (PM2.5) levels and hospital admissions for cardiovascular diseases (CVD) in Kaohsiung, Taiwan. Hospital CVD (including ischemic heart disease [IHD], stroke, congestive failure [CHF], arrhythmias) ambient air pollution data Kaohsiung were obtained the period from 2006–2010. The relative risk of estimated using a case-crossover approach, controlling weather variables, day week, seasonality, long-term...

10.1080/15287394.2014.960044 article EN Journal of Toxicology and Environmental Health 2015-02-12

Many learners of English as a foreign language often feel that learning spoken is frustrating and quite difficult, especially when they have to talk English-speaking foreigners. In general, because are unfamiliar with the mode worried about making grammatical errors, very scared speak English. Furthermore, reading differ in many ways. For instance, seeing text containing new words, can stop look up words dictionary. Additionally, passage be read multiple times by understand it. Conversely,...

10.1080/10494820.2021.1960864 article EN Interactive Learning Environments 2021-08-13

Abstract The consumption of alcohol, tobacco and betel quid has been found to be an important contributor esophageal squamous cell carcinoma (ESCC) in Taiwan. genotoxic effect the ADH1B ALDH2 genes modulating individual's alcohol‐metabolizing capacity on ESCC may linked drinking behavior, intake pattern other exogenous factors. To investigate interplay these genetic environmental factors determining risk ESCC, a multicenter case‐control study was conducted. Here, 406 patients with...

10.1002/ijc.23264 article EN cc-by International Journal of Cancer 2007-11-21

Melioidosis results from an infection with the soil-borne pathogen Burkholderia pseudomallei, and cases of melioidosis usually cluster after rains or a typhoon. In endemic area Taiwan, B. pseudomallei is primarily geographically distributed in cropped fields northwest this area, whereas are densely populated district southeast. We hypothesized that contaminated generated aerosols which were carried by northwesterly wind to southeastern district. collected soil aerosol samples 72 km2 land,...

10.1371/journal.pntd.0003834 article EN cc-by PLoS neglected tropical diseases 2015-06-10

Contaminants of emerging concern such as organophosphate flame retardants (OPFRs) are associated with atmospheric fine particles (PM2.5), which pose the greatest health risk in world. However, few surveys have explored interaction between PM2.5 and OPFRs residential paired indoor/outdoor environments. 11 priority were investigated across 178 indoor outdoor air samples taken from 89 children's households southern Taiwan, cold warm seasons. This involved exploring their associations building...

10.1016/j.envint.2023.107871 article EN cc-by-nc-nd Environment International 2023-03-12

In spring, windblown dust storms originating in the deserts of Mongolia and China travel to Taipei city. These occurrences are known as Asian storm (ADS) events. The objective this study was assess possible associations constituents ADS with hospital pneumonia admissions residents Taipei, Taiwan, during period 1996–2001. Fifty-four episodes were identified classified index days. Daily on days compared comparison Two for each day, 7 d before after days, selected. results indicated a...

10.1080/15287390802114808 article EN Journal of Toxicology and Environmental Health 2008-08-06

The relationship between breast cancer mortality and air pollution was examined using an ecological design. study areas consisted of 61 municipalities in Taiwan. Air quality data for recorded concentrations fine particulate matter (PM2.5) from 2006–2009 were obtained as a marker traffic emissions used proxy polycyclic aromatic hydrocarbons (PAHs) exposure. Age-standardized rates calculated the years 1999–2008. A weighted multiple regression model to calculate adjusted risk ratio relation...

10.4209/aaqr.2011.09.0155 article EN Aerosol and Air Quality Research 2012-01-01

Among the air pollutants, particulate matter with an aerodynamic diameter less than 2.5 um (PM2.5) is of particular interest to environmental medicine as epidemiologic studies consistently reported that long-term exposure PM2.5 associated increased risk premature death in adults. Life expectancy a well-documented and important measure overall public health policy. However, few investigators examined relationship between levels adult life expectancy. In this Taiwan-wide study, county-level...

10.1080/15287394.2019.1658386 article EN Journal of Toxicology and Environmental Health 2019-07-18

Associations exist between fine particulate matter (PM2.5) exposure and impaired kidney function. However, the specific mechanisms components causing renal damage remain unclear. PM2.5 was collected from an industrial a rural area. Mice were categorized according to exposure, biochemical, western blotting, histological, immunohistochemical analyses performed evaluate impact of constituents on their kidneys. To assess different inflammatory responses, study conducted by exposing murine...

10.1016/j.ecoenv.2025.117808 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2025-02-01

A series of HIV protease inhibitors containing a novel C2 symmetrical "aminodiol" core structure were prepared from amino acid starting materials. The ability the aminodiols to inhibit replication in cell culture is comparable their isolated enzyme, result compatible with good membrane penetration by this class compounds. Optimization structure-activity led aminodiol 9a (Ki = 100 nM; ED50 (HIV-1) 80 nM) P1/P1 benzyl and P2/P2 Boc substituents. Compound selective inhibitor versus other...

10.1021/jm00038a005 article EN Journal of Medicinal Chemistry 1994-06-01

Influenza viruses cause pandemics in humans. The aim of this study was therefore to evaluate filter/real-time qPCR quickly and accurately determine quantify the airborne influenza avian virus. In study, sampling stress filtration virus storage effects for both extracted RNA were evaluated laboratory. Then, collection efficiencies open-face closed-face filter cassettes compared a wet poultry market. From July 8 August 19, 2006, total 36 air samples quantified by qPCR. recovery rate on stored...

10.1080/02786820802621232 article EN Aerosol Science and Technology 2009-01-14

Purpose. Aromatherapy massage is an alternative treatment in reducing the pain of cancer patients. This study was to investigate whether aromatherapy could improve Methods. We searched PubMed and Cochrane Library for relevant randomized controlled trials without language limitations between 1 January 1990 31 July 2015 with a priori defined inclusion exclusion criteria. The search terms included aromatherapy, essential oil, pain, ache, cancer, tumor, carcinoma. There were 7 studies which met...

10.1155/2016/9147974 article EN cc-by Evidence-based Complementary and Alternative Medicine 2016-01-01

Traditional culture and microscopy methods for evaluation of bioaerosols are slow, tedious, rather imprecise. In this study, the application flow cytometry that was combined with a fluorescent technique (FCM/FL) evaluated as to quickly accurately determine quantify total concentration viability bioaerosols. The optimal conditions five dyes [acridine orange (AO), SYTO-13, propidium iodide (PI), YOPRO-1, 5-cyano-2,3-ditolytetrazolium chloride (CTC)] used in FCM/FL were determined laboratory...

10.1039/b505224f article EN Journal of Environmental Monitoring 2005-01-01

Background Melioidosis is a severe bacterial infection caused by Burkholderia pseudomallei with high case-fatality rate. Epidemiological and animal studies show the possibility of inhalation transmission. However, no B. concentrations in ambient air have been researched. Here, we developed method to quantify then measured during typhoon season non-typhoon determine factors influencing levels. Methods We quantified using filter/real-time qPCR Zoynan Region Kaohsiung, southern Taiwan....

10.1371/journal.pntd.0002877 article EN cc-by PLoS neglected tropical diseases 2014-05-29

Although culture-based analysis remains the primary method for environmental bioaerosol analysis, better understanding and quantifying of bioaerosols both culture- nonculture-based methods should be used compared. Here, flow cytometry with fluorochrome (FCM/FL) was applied to evaluate sampling performance impingement (AGI-30 all-glass impinger) filtration (track-etched polycarbonate filter) different types fluorescent dye staining (cell membrane integrity metabolism) then compared a...

10.1080/027868290925534 article EN Aerosol Science and Technology 2005-03-01

To investigate the relationship between air pollution and risk of death attributed to gastric cancer, a matched cancer case-control study was conducted using deaths that occurred in Taiwan from 2004 through 2008. Data for all eligible were obtained compared control group consisting individuals who died causes other than neoplasms diseases associated with gastrointestinal (GIT) disorders. The controls pair-matched cases by gender, year birth, death. Each randomly selected set possible each...

10.1080/15287394.2011.590100 article EN Journal of Toxicology and Environmental Health 2011-07-28

Abstract Mycobacterium tuberculosis infection remains one of the major public health issues worldwide. Current qualitative assays (only positive or negative results) do not provide comprehensive information regarding risk M. tuberculosis. This study attempted to develop a quantitative assay measure air concentration in care setting. A total 22 samples were taken from pressure isolation rooms patients. The was filtered through Nuclepore filter with sampling time 8 h. DNA tuberculosisin these...

10.1080/027868290945767 article EN Aerosol Science and Technology 2005-04-01

This study was undertaken to evaluate whether endoscopic sinus surgery (ESS) with a microdebrider had an impact on complication rates, and facilitate the determination of factors associated complications in patients who underwent ESS at tertiary referral center Taiwan.This investigation retrospective literature review. We analyzed 997 consecutive Mackay Memorial Hospital Taipei, Taiwan from January 2006 through February 2010. All data including those patient medical information, peri-...

10.1016/j.jcma.2015.11.001 article EN cc-by-nc-nd Journal of the Chinese Medical Association 2015-12-17

Jumping on the bed is a favorite behavior of children; however, no study has investigated increased air pollutants resulting from jumping bed. Therefore, we aimed to investigate elevated concentrations particulate matter (PM) and bioaerosols making Simulation was performed at sixty schoolchildren's houses in Taiwan. PM10, PM2.5, PM1 (PM with aerodynamic diameter less than 10, 2.5, 1 μm, respectively) airborne bacteria, fungi endotoxin were simultaneously measured over simulation background...

10.1016/j.envpol.2018.11.053 article EN cc-by-nc-nd Environmental Pollution 2018-11-21

Outbreaks of avian influenza virus (AIV) have raised public concerns recently. Airborne AIV has been evaluated in live poultry markets and case farms; however, no study discussed airborne ambient air the winter habitats migratory birds. Therefore, this aimed to evaluate AIV, specifically H5, H7, H9, a critical habitat birds assess factors influencing transmission provide novel insights into epidemiology influenza. A total 357 samples were collected Aogu Wetland, Taiwan, Republic China,...

10.1021/acs.est.2c04528 article EN Environmental Science & Technology 2022-10-26
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