- Effects and risks of endocrine disrupting chemicals
- Melamine detection and toxicity
- Esophageal Cancer Research and Treatment
- Carcinogens and Genotoxicity Assessment
- Mercury impact and mitigation studies
- Air Quality and Health Impacts
- Heavy Metal Exposure and Toxicity
- Helicobacter pylori-related gastroenterology studies
- Oral Health Pathology and Treatment
- Lung Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Cervical Cancer and HPV Research
- Toxic Organic Pollutants Impact
- Epigenetics and DNA Methylation
- Alcohol Consumption and Health Effects
- Cardiac Imaging and Diagnostics
- Glutathione Transferases and Polymorphisms
- Cancer-related gene regulation
- Radiomics and Machine Learning in Medical Imaging
- Esophageal and GI Pathology
- Health, Environment, Cognitive Aging
- Head and Neck Cancer Studies
- Liver Disease Diagnosis and Treatment
- Cancer-related Molecular Pathways
- Gene Regulatory Network Analysis
Kaohsiung Medical University
2016-2025
Kaohsiung Medical University Chung-Ho Memorial Hospital
2016-2025
Education Department of Fujian Province
2025
Peking University
2024
National Health Research Institutes
2000-2023
Jiangsu Provincial Center for Disease Control and Prevention
2010-2023
Peking University Shenzhen Hospital
2023
Nanjing Medical University
2023
Second Affiliated Hospital of Zhejiang University
2023
National Sun Yat-sen University
2008-2022
Purpose: To prospectively evaluate accuracy of multi–detector row computed tomographic (CT) images for preoperative staging gastric cancer by using surgical and histopathologic results as reference standards. Materials Methods: This study had institutional review board approval; informed consent was obtained from all patients. Multi–detector CT included acquisition virtual gastroscopy after air distention contrast material–enhanced dynamic transverse multiplanar reformation (MPR) water...
Abstract A multicenter case‐control study was conducted in northern and southern Taiwan to clarify the independent combined effects of alcohol intake, tobacco smoking betel quid chewing on risk esophageal cancer. total 513 patients with newly diagnosed histopathologically confirmed squamous cell carcinoma esophagus 818 gender, age hospital‐matched controls were included. We found a significant dose‐response relationship between duration intensity consumption 3 substances development this...
Nanoemulsion as a strategy for improving the oral bioavailability and anti-inflammatory activity of andrographolide Ching-Chi Yen,1 Yi-Chen Chen,1 Ming-Tsang Wu,2 Chia-Chi Wang,1,3 Yu-Tse Wu1,4 1School Pharmacy, College Kaohsiung Medical University, Kaohsiung, Taiwan; 2Chinese Medicine Department, Ditmanson Foundation, Chiayi Christian Hospital, City, 3PhD Program in Toxicology, 4Department Research, University Taiwan Background: Andrographolide (AG), compound with low water solubility,...
Coronary Arterial Calcification on Low-Dose Ungated MDCT for Lung Cancer Screening: Concordance Study with Dedicated Cardiac CTMing-Ting Wu1 2, Pinchen Yang3, Yi-Luan Huang1 Jian-Shyong Chen2, Chiung-Chen Chuo2, Chinson Yeh4 and Ruey-Sheng Chang2 5Audio Available | Share
Objectives We evaluated the association between exposure to polycyclic aromatic hydrocarbons (PAHs) and immunological measurements using blood samples from coke oven workers exposed high low PAH levels. Methods A population-based cross-sectional study was conducted 2008–2009 with steel-rolling as control groups, respectively. Questionnaires on basic demographic information were administered. Personal breathing zone urine collected quantify personal intake biological response doses....
In a subset of lung adenocarcinomas, the epidermal growth factor receptor (EGFR) is activated by kinase domain mutations and/or gene amplification, but interaction between two types abnormalities complex and unclear. For this study, we selected 99 consecutive never-smoking women East Asian origin with adenocarcinomas that were characterized histologic subtype. We analyzed EGFR PCR-capillary sequencing, copy number fluorescence chromogenic in situ hybridization quantitative PCR, expression...
Abstract The consumption of alcohol, tobacco and betel quid has been found to be an important contributor esophageal squamous cell carcinoma (ESCC) in Taiwan. genotoxic effect the ADH1B ALDH2 genes modulating individual's alcohol‐metabolizing capacity on ESCC may linked drinking behavior, intake pattern other exogenous factors. To investigate interplay these genetic environmental factors determining risk ESCC, a multicenter case‐control study was conducted. Here, 406 patients with...
Background The purpose of this study was to examine the relationship phthalates exposure with thyroid function in pregnant women and their newborns. Methods One hundred forty-eight Taiwanese maternal infant pairs were recruited from E-Da hospital southern Taiwan between 2009 2010 for analysis. One-spot urine samples blood third trimester cord at delivery collected. Nine phthalate metabolites determined by triple quadrupole liquid chromatography tandem mass spectrometry, whereas serum used...
The protective effect of statin on Alzheimer disease (AD) is still controversial, probably due to the debate about when start use and lack any large-scale randomized evidence that actually supports hypothesis. purpose this study was examine early mild-to-moderate AD in total Taiwanese population. This a population-based case-control study, using population citizens seen general medical practice; therefore, findings can be applied patients were those with newly diagnosed dementia (ICD-9...