A5038393119- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Kidney Stones and Urolithiasis Treatments
- Urinary Bladder and Prostate Research
- Urological Disorders and Treatments
- Pediatric Urology and Nephrology Studies
- Epigenetics and DNA Methylation
- Renal cell carcinoma treatment
- Hormonal and reproductive studies
- Prostate Cancer Diagnosis and Treatment
- Ureteral procedures and complications
- Ferroptosis and cancer prognosis
- Prostate Cancer Treatment and Research
- Urologic and reproductive health conditions
- Sexual function and dysfunction studies
- Pelvic floor disorders treatments
- Cancer, Lipids, and Metabolism
- Cancer-related Molecular Pathways
- Peptidase Inhibition and Analysis
- Infectious Disease Case Reports and Treatments
- Adrenal and Paraganglionic Tumors
- Urinary Tract Infections Management
- Minimally Invasive Surgical Techniques
- Renal and related cancers
- Multiple and Secondary Primary Cancers
Kaohsiung Medical University Chung-Ho Memorial Hospital
2016-2025
Kaohsiung Medical University
2016-2025
Chinese People's Liberation Army
2025
First Affiliated Hospital of Kunming Medical University
2024-2025
Kunming Medical University
2024-2025
Qingdao University
2025
Qingdao Municipal Hospital
2025
Tianjin Medical University
2024
Southern Medical University
2024
Mackay Memorial Hospital
2024
Abstract Aims The aims of the present study were to investigate voiding patterns, tissue constituents and expressions cyclooxygenase‐2 (COX‐2) nitric oxide synthase (NOS) involved in ketamine‐induced ulcerative cystitis rat urinary bladder. Methods Thirty Sprague–Dawley rats distributed into three groups which received saline or ketamine (25 mg/kg/day) for a period 14 28 days. In each group, cystometry was performed weekly concentration its metabolites (norketamine) assayed....
Background To increase the survival span after dialysis in patients with end-stage renal disease (ESRD), identifying specific cancer risks is crucial screening of these patients. The aim this study was to investigate various cancers an incident group comparison a non-dialysis group. Method We conducted nationwide cohort by using data from Taiwan National Health Insurance Research Database. Patients who initially received long-term between January 1997 and December 2004, were selected defined...
Previously, p53 (also known as TP53) gene mutations have been shown to be frequently detected in highly malignant urothelial cancers. Evidence has accumulating that the disruption of normal function may lead genomic instability, including predisposition amplification. Furthermore, abrogated by MDM2 (murine double minute-2) amplification some human tumors. Our purpose was investigate relationship between proto-oncogene and alteration cancers examining existence 14 other proto-oncogenes 50...
Ketamine abusers develop severe lower urinary tract symptoms. The major aims of the present study were to elucidate ketamine-induced ulcerative cystitis and bladder apoptosis in association with oxidative stress mediated by mitochondria endoplasmic reticulum (ER). Sprague-Dawley rats distributed into three different groups, which received normal saline or ketamine for a period 14 28 days, respectively. Double-labeled immunofluorescence experiments performed investigate tight junction...
Background: Urothelial carcinoma (UC) commonly occurs in the urinary bladder (UB) and rarely upper tract (UT).Its molecular pathogenesis, however, remains obscure.Though constitutive phosphorylation of Signal Transducer Activator Transcription 5 (STAT5) is an important part carcinogenesis generally, researchers have not systematically investigated this process specifically relation to UC.The present study addresses gap.Through data mining a published transcriptomic database UBUCs (GSE32894),...
Several groups have proposed features to identify low-risk patients who may benefit from endoscopic kidney-sparing surgery in upper tract urothelial carcinoma (UTUC).To evaluate standard risk stratification features, develop an optimal model ≥pT2/N+ stage at radical nephroureterectomy (RNU), and compare it with the existing unvalidated models.This was a collaborative retrospective study that included 1214 underwent ureterorenoscopy biopsy followed by RNU for nonmetastatic UTUC between 2000...
Numerous microorganisms residing in the gastrointestinal and genitourinary tracts affect host health. We investigated stool voided urine samples collected from patients with benign prostatic hyperplasia (BPH) or prostate cancer (PC) a control group to explore potential relationship between human microbiota disease, aimed identify correlations pathogenic taxonomic units. studied microbial composition using 16S rRNA sequencing operational units (OTUs). Extracted genome was amplified filtered...
Upper tract urothelial carcinoma (UTUC) presents a significant recurrence risk following radical nephroureterectomy (RNU). Patients on dialysis may experience unique clinical trajectories due to uremic states and altered immune responses. To evaluate the impact of intravesical survival outcomes in patients with UTUC undergoing RNU, identify predictive factors influencing prognosis. A retrospective cohort study analyzed 402 non-metastatic treated RNU between 2001 2014. were stratified into (n...
The objective of the present study was to evaluate impact dialysis on patients with upper tract urothelial carcinoma (UTUC) who are undergoing surgical intervention, as well identify predictive factors linked contralateral recurrence. A retrospective review conducted underwent radical nephroureterectomy (RNU) for non-metastatic UTUC at our institution from 2000 2013. recurrence rate calculated using Kaplan-Meier method, and multivariate logistic regression analysis employed examine...
Chronic kidney disease (CKD) due to type 2 diabetes mellitus (T2DM) has emerged as a significant global health burden, with rising incidence and prevalence rates observed over the past decades. We utilized latest data from Global Burden of Disease Study (GBD) 2021. Firstly, we reported number incidence, prevalence, deaths, Disability-Adjusted Life Years (DALYs) attributed CKD T2DM, accompanied by their respective Age-Standardized Rates (ASRs), for year This analysis encompassed perspective...
Renal function after radical nephroureterectomy (RNU) in patients with advanced upper tract urothelial carcinoma (UTUC) is an indicator of eligibility for postoperative chemotherapy. The present study aimed to utilize machine learning predicting renal status RNU and investigate the contribution several features this prediction. retrospective included 764 medical records non‑metastatic UTUC who received from 2008 2022. were divided into training (n=534) testing (n=230) datasets. Several...
Purpose: Existing T3 subclassifications for upper tract urothelial cancer (UTUC) are limited by heterogeneity and a primary focus on renal pelvis tumors. Our study aimed to propose novel pT3 subclassification system specifically tailored UTUC patients. Materials Methods: This analyzed 120 cases from Taiwanese multicenter registry, using standardized pathology report single pathologist evaluation. Results: Univariate analysis revealed survival differences based existing subclassifications....