- melanin and skin pigmentation
- Skin Protection and Aging
- Retinoids in leukemia and cellular processes
- Arsenic contamination and mitigation
- Dermatologic Treatments and Research
- Dermatology and Skin Diseases
- Heavy Metal Exposure and Toxicity
- Allergic Rhinitis and Sensitization
- Circadian rhythm and melatonin
- Psoriasis: Treatment and Pathogenesis
- Laser Applications in Dentistry and Medicine
- Contact Dermatitis and Allergies
- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Cancer-related Molecular Pathways
- Skin and Cellular Biology Research
- Cell Adhesion Molecules Research
- Systemic Sclerosis and Related Diseases
- Nonmelanoma Skin Cancer Studies
- NF-κB Signaling Pathways
- Energy and Environment Impacts
- Asthma and respiratory diseases
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Trace Elements in Health
- Dermatological and Skeletal Disorders
Kaohsiung Medical University
2014-2024
National Health Research Institutes
2007-2024
Kaohsiung Medical University Chung-Ho Memorial Hospital
2012-2023
Research Center for Applied Science, Academia Sinica
2016
Kaohsiung Municipal Hsiao-Kang Hospital
2011
Dalian Polytechnic University
2008-2009
National Museum of Marine Biology and Aquarium
2007-2008
National Taiwan University Hospital
2004-2007
National Taiwan University
2003-2006
Kaohsiung Armed Forces General Hospital
1999
Neutrophil extracellular traps (NETs) have been implicated in the development of certain immune-mediated diseases, but their role psoriasis has not clearly defined. Human β-defensin-2 (HBD-2) is an important antimicrobial peptide overexpressed epidermis. We evaluated whether amount NETs increased and determined effect on HBD-2 production epidermal keratinocytes. Using fluorescent microscopy, we found that patients with (n = 48) had higher NETotic cells peripheral blood compared to healthy...
The lesions of nine patients with early striae distensae (SD) during puberty were examined by light and electron microscopy. Specific changes seen in very stage SD, clinically uninvolved skin 0.5 to 3 cm remote from the edge long axis SD lesions. Sequential elastolysis accompanied mast cell degranulation appeared first, followed an influx activated macrophages that enveloped fragmented elastic fibers. relationships among fibers, cells, present work suggest their critical roles process...
Abstract: Narrow‐band ultraviolet‐B (UVB) radiation is an effective treatment for vitiligo vulgaris. However, the mechanisms of narrow‐band UVB in inducing repigmentation lesions are not thoroughly clarified. The purpose our study was to investigate effects irradiation on melanocyte proliferation and migration vitro . Our results showed that cell counts as well [3H]thymidine uptake melanocytes were significantly enhanced by UVB‐irradiated keratinocyte supernatants. In these supernatants, a...
Background: The aims of this study were to examine the direct and indirect effects posttraumatic stress disorder (PTSD), major depressive (MDD), disaster-exposure experience, gender, perceived family support on suicide risk (including ideation attempt) in adolescents 3 months after they had experienced Typhoon Morakot-associated mudslides Taiwan using a structural equation model (SEM). Methods: Two hundred seventy-one worst affected mountainous regions southern recruited. Suicide diagnoses...
Abstract: The term 'hand dermatitis' describes inflammatory skin condition localized to the hands. Nurses working at hospital settings are prone develop hand dermatitis. current study aimed evaluate whether certain genetic polymorphisms were associated with development of atopic eczema or non-atopic dermatitis in Taiwanese population. Kaohsiung Medical University Hospital recruited. Atopic eczema, and normal control groups identified. serine protease inhibitor Kazal type 5 (SPINK5),...