A5039798635- Analytical Chemistry and Chromatography
- Microfluidic and Capillary Electrophoresis Applications
- Hydrology and Watershed Management Studies
- Environmental Toxicology and Ecotoxicology
- Innovative Microfluidic and Catalytic Techniques Innovation
- Mass Spectrometry Techniques and Applications
- Crystallization and Solubility Studies
- Soil and Water Nutrient Dynamics
- Soil erosion and sediment transport
- Archaeology and ancient environmental studies
- Fish Ecology and Management Studies
- Healthcare Operations and Scheduling Optimization
- Hydrology and Sediment Transport Processes
- Heavy metals in environment
- Plant and animal studies
- Planetary Science and Exploration
- Insect and Pesticide Research
- Ultrasound in Clinical Applications
- Soil and Unsaturated Flow
- Aquatic Ecosystems and Phytoplankton Dynamics
- Protein purification and stability
- Water Systems and Optimization
- Atmospheric chemistry and aerosols
- Pesticide Residue Analysis and Safety
- Christian Theology and Mission
Millsaps College
2008-2025
State Street (United States)
2001-2025
Yale University
2024
University of York
2024
Health and Safety Executive
2023-2024
Northwestern University
2023
University of Chicago
2020
Philips (United States)
2020
University of Edinburgh
2019
Wokingham Hospital
2019
For many drugs, only racemic mixtures are available for clinical use. Because different stereoisomers of drugs often cause physiological responses, the use pure isomers could elicit more exact therapeutic effects. Differential complexation a variety drug by immobilized β-cyclodextrin was investigated. Chiral recognition and resolution were observed with number compounds from such clinically useful classes as β-blockers, calcium-channel blockers, sedative hypnotics, antihistamines,...
ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTChiral Separations: Fundamental Review 2010Timothy J. Ward* and Karen D. WardView Author Information Millsaps College, 1701 N. State Street, Box 150306, Jackson, Mississippi 39210* To whom correspondence should be addressed. Phone: (601) 974-1405. Fax: 974-1401. E-mail: [email protected]Cite this: Anal. Chem. 2010, 82, 12, 4712–4722Publication Date (Web):May 24, 2010Publication History Published online24 May 2010Published inissue 15 June...
Abstract Cyclodextrin chiral phases have been shown to be widely applicable for the separation of enantiomers, diastereomers, structural isomers and routine compounds. Two innovations recently occured in this field. First, efficiency selectivity β-cyclodextrin column has improved. Second, compatable TLC plates which produce separations analogous columns developed. These results are discussed subsequent a brief review published work. In addition, mechanism on cyclodextrin bonded media,...
ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTChiral SeparationsTimothy J. Ward* and Beth Ann BakerView Author Information Millsaps College 1701 North State Street, Box 150306, Jackson, Mississippi 39210* To whom correspondence should be addressed. Phone: (601) 974-1405 . Fax: 601) 974-1401. E-mail: [email protected]Cite this: Anal. Chem. 2008, 80, 12, 4363–4372Publication Date (Web):May 16, 2008Publication History Published online16 May 2008Published inissue 1 June...
Abstract Klebsiella pneumoniae has been classified into two types, classical K. (cKP) and hypervirulent (hvKP). cKP isolates are highly diverse important causes of nosocomial infections; they include globally disseminated antibiotic-resistant clones. hvKP sensitive to most antibiotics but virulent, causing community-acquired infections in healthy individuals. The virulence phenotype is associated with pathogenicity loci responsible for siderophore hypermucoid capsule production. Recently,...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDerivatized cyclodextrins immobilized on fused-silica capillaries for enantiomeric separations via capillary electrophoresis, gas chromatography, or supercritical fluid chromatographyDaniel W. Armstrong, Yubing. Tang, Timothy. Ward, and Molly. NicholsCite this: Anal. Chem. 1993, 65, 8, 1114–1117Publication Date (Print):April 15, 1993Publication History Published online1 May 2002Published inissue 15 April...
To investigate the associations between assignment of an oral hygiene aide staff member and risk factors for mortality from pneumonia in a nursing home to test hypothesis that this care would affect incidence pneumonia.Electronic medical records.Nursing home.One hundred forty-three residents Veterans Affairs Medical Center (VAMC) home.The electronic records 143 VAMC were analyzed pneumonia. A certified assistant had been assigned provide on two four wards. Researchers performed longitudinal...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFor capillary electrophoresisTimothy J. WardCite this: Anal. Chem. 1994, 66, 11, 632A–640APublication Date (Print):June 1, 1994Publication History Published online22 September 2008Published inissue 1 June 1994https://pubs.acs.org/doi/10.1021/ac00083a001https://doi.org/10.1021/ac00083a001research-articleACS PublicationsRequest reuse permissionsArticle Views241Altmetric-Citations63LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMicellar effects on molecular diffusion: theoretical and chromatographic considerationsDaniel W. Armstrong Timothy J. WardCite this: Anal. Chem. 1986, 58, 3, 579–582Publication Date (Print):March 1, 1986Publication History Published online1 May 2002Published inissue 1 March 1986https://pubs.acs.org/doi/10.1021/ac00294a019https://doi.org/10.1021/ac00294a019research-articleACS PublicationsRequest reuse permissionsArticle...
A diverse laboratory population of Daphnia magna Straus was established by combining individuals from eight sources. Artificial selection for increased resistance to the acute toxic effects cadmium performed, and after generations, average median effective concentration 61 180 microg/L. No differences in life span, offspring production, time first brood, number or intrinsic rate increase (r) were observed between cadmium-adapted controls under ideal conditions temperature feeding ration...
Chemical analyses of organic residues in fragments pottery from the large site Cahokia and surrounding smaller sites Illinois reveal theobromine, caffeine, ursolic acid, biomarkers for species Ilex (holly) used to prepare ritually important Black Drink. As recorded during historic period, men consumed Drink portions American Southeast ritual purification. This first demonstrated discovery occurs beaker vessels dating between A.D. 1050 1250 Cahokia, located far north known range holly times....
Excellent separations were achieved using a coated column to suppress electroosmotic flow and employing countercurrent process between chiral selector racemic solute. Using the macrocyclic antibiotic vancomycin as in capillary electrophoresis resolution of nonsteroidal anti inflammatories dansyl amino acids was achieved. Improvement sensitivity due elimination background absorbance increased efficiency removal wall adsorption effects are both this technique.
Five models are investigated for determining the percentage delivery of sediment to streams shallow landslides that evolve into debris flows. Models I–III based on flow run-out distance, Model IV snow avalanche distance. For these it is assumed 100% slopes above 10° and zero below 4°. intermediate slopes, distance estimate. V, derived from field data, estimates directly without need slope conditions. The model performances using 100 hypothetical hillslopes a limited database landslide in...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEnantiomeric resolution and chiral recognition of racemic nicotine analogs by .beta.-cyclodextrin complexation. Structure-enantiomeric relationships in host-guest interactionsJeffrey I. Seeman, Henry V. Secor, Daniel W. Armstrong, Karen D. Timmons, Timothy J. WardCite this: Anal. Chem. 1988, 60, 19, 2120–2127Publication Date (Print):October 1, 1988Publication History Published online1 May 2002Published inissue 1 October...