A5101513377- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Nuclear physics research studies
- Quantum Chromodynamics and Particle Interactions
- Cardiac electrophysiology and arrhythmias
- Acute Myocardial Infarction Research
- Radioactive contamination and transfer
- Radiation Detection and Scintillator Technologies
- Particle physics theoretical and experimental studies
- Radioactivity and Radon Measurements
- Coronary Interventions and Diagnostics
- Nuclear Physics and Applications
- Radioactive element chemistry and processing
- Atomic and Molecular Physics
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Infectious Diseases and Mycology
- Molecular Spectroscopy and Structure
- Coronary Artery Anomalies
- Advanced Algebra and Geometry
- Liver Disease and Transplantation
- Bartonella species infections research
Fudan University
2021-2025
Sun Yat-sen University
2021-2025
Zhongshan Hospital
2021-2025
The First Affiliated Hospital, Sun Yat-sen University
2021-2025
Hangzhou First People's Hospital
2015-2024
Xuzhou Medical College
2024
Second People’s Hospital of Huai’an
2024
Tongji University
2023-2024
Adrian College
2023
Directorate of Medicinal and Aromatic Plants Research
2023
Abstract Aims Patients with heart failure preserved ejection fraction (HFpEF) and atrial fibrillation (AF) have worse clinical outcomes than those sinus rhythm (SR). We aim to investigate whether maintaining SR in patients HFpEF through a strategy such as AF ablation would improve outcomes. Methods results This is cohort study that analysed 1034 (median age 69 [63–76] years, 46.2% [478/1034] female) AF. Of these, 392 who underwent first-time were assigned the group, remaining 642 patients,...
Ventricular arrhythmia (VA) originating from the left ventricular summit (LVS) poses particular challenges, with higher rates of ablation failure. To further evaluate anatomical approach subaortic region for LVS VAs and their electrophysiological characteristics. The study enrolled 27 consecutive patients sympatomatic who received an R-L ILT in our center. Three different mapping results were obtained as earliest activation sites (EAS) observed RVOT (group 1), 2), epicardial 3),...
Abstract Background The severe unfavorable effects of doxorubicin on the heart restrict its clinical usage. Numerous investigations document that cyclic GMP-AMP synthase (cGAS) activator interferon genes (STING) cascade influences inflammation along with immune response in a variety diseases. pathophysiological function cGAS-STING Doxorubicin-induced cardiomyopathy (DIC) is, nevertheless, unknown. Methods In vivo, cardiotoxicity was triggered by single dose intra-peritoneal inoculation (15...
Based on the beyond-mean-field Skyrme-Hartree-Fock model, we investigate energy spectra and possible cluster structure in $^{12}\mathrm{C}$ its $\mathrm{\ensuremath{\Lambda}}$ hypernucleus $_{\phantom{\rule{0.16em}{0ex}}\phantom{\rule{0.16em}{0ex}}\mathrm{\ensuremath{\Lambda}}}^{13}\mathrm{C}$. The up-to-date Skyrme-type $N\mathrm{\ensuremath{\Lambda}}$ interaction SLL4 reduced $NN$ SGII are employed. Low-lying of $^{12}\mathrm{C}$, including lowest five ${0}^{+}$ states, predicted discussed...
Purpose: LINC00680 was reported to be involved in various cancers through multiple mechanisms. Therefore, we intended investigate its role the progression of non-small cell lung cancer (NSCLC). Materials and Methods: Firstly, quantitative real-time polymerase chain reaction (qRT-PCR) used test NSCLC tissue lines. Subsequently, A549 H1299 cells were transfected with overexpressing plasmids their proliferation colony formation apoptosis tested by Transwell assay flow cytometry. In addition,...
Myocardial hypertrophy plays an essential role in the structural remodeling of heart and progression to failure (HF). There is urgent need understand mechanisms underlying cardiac develop treatments for early intervention. Dangshen Erling decoction (DSELD) a clinically used formula Chinese medicine treating coronary disease patients with HF. However, mechanism by which DSELD produces its cardioprotective effects remains largely unknown. This study explored on myocardial hypotrophy both vitro...
The $\mathrm{\ensuremath{\Lambda}}\mathrm{\ensuremath{\Lambda}}$ pairing effects in spherical and deformed multi-$\mathrm{\ensuremath{\Lambda}}$ hyperisotopes are investigated the framework of Skyrme-Hartree-Fock approach employing a $\ensuremath{\delta}$ force with strength $\mathrm{\ensuremath{\Lambda}}$ hyperons being $4/9$ that for nucleons. For hyperisotopes, occurrences magic numbers $\ensuremath{-}S=2$, 8, 18, 20, 34, 58, 68, 70, which attributed to Woods-Saxon-like hyperon potential,...
Limited data are available on the outcomes of cryoballoon ablation (CBA)-based pulmonary vein isolation (PVI) for atrial fibrillation (AF) in patients with heart failure (HF) preserved ejection fraction (HFpEF) and mildly reduced (HFmrEF). The present study aimed to evaluate safety effectiveness CBA such patients.Consecutive AF referred CBA-based PVI from two highly experienced electrophysiology centres were included this retrospective study. Of 651 undergoing CBA, 471 cases divided into...
The deformations of multi-$\la$ hypernuclei corresponding to even-even core nuclei ranging from $^8$Be $^{40}$Ca with 2, 4, 6, and 8 hyperons are studied in the framework deformed Skyrme-Hartree-Fock approach. It is found that reduced when adding 2 or $\la$ hyperons, but enhanced 4 6 hyperons. These differences attributed fact filled gradually into three $p$ orbits, which [110]1/2$^-$ orbit prolately degenerate [101]1/2$^-$ [101]3/2$^-$ orbits oblately deformed.
Enhanced late sodium current (INaL) is reportedly related to an increased risk of atrial fibrillation (AF). Moricizine, as a widely used anti-arrhythmia drug for suppressing ventricular tachycardia, has also been shown prevent paroxysmal AF. However, the mechanism its therapeutic effect remains poorly understood.Angiotensin II (Ang II) was induced in C57Bl/6 mice (male wild-type) 4 weeks increase susceptibility AF, and acetylcholine-calcium chloride induce The whole-cell patch-clamp...
Charmed ${\mathrm{\ensuremath{\Lambda}}}_{c}^{+}$ hypernuclei are investigated in the framework of deformed Skyrme-Hartree-Fock approach. Their ground-state bulk properties, single-particle energy levels, potential curves, as well existence limit charmed studied with particular regard to effects deformation. ${\mathrm{\ensuremath{\Lambda}}}_{c}^{+}\phantom{\rule{4pt}{0ex}}1p$ states found be strongly bound, nuclei.
The influence of hyperons on localized clusters is studied in deformed nuclei $^{20}\mathrm{Ne}$ and $^{28}\mathrm{Si}$ the spherical nucleus $^{40}\mathrm{Ca}$ by employing Skyrme-Hartree-Fock approach localization function. It found that $p$ state initially tend to occupy orbitals with shapes similar core nucleus. exhibits a robust prolate configuration characterized an $\ensuremath{\alpha}{\ensuremath{-}}^{12}\mathrm{C}\ensuremath{-}\ensuremath{\alpha}$ cluster, while displays less...