A5063956962- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Peripheral Neuropathies and Disorders
- SARS-CoV-2 and COVID-19 Research
- Clostridium difficile and Clostridium perfringens research
- Escherichia coli research studies
- Antibiotic Resistance in Bacteria
- Bacteriophages and microbial interactions
- Genomics and Phylogenetic Studies
- Cancer Research and Treatments
- Bacterial Identification and Susceptibility Testing
- Veterinary medicine and infectious diseases
- Viral Infections and Immunology Research
- Listeria monocytogenes in Food Safety
- RNA Interference and Gene Delivery
- Influenza Virus Research Studies
Hospital Nacional Cayetano Heredia
2021
Erasmus MC
2021
Johns Hopkins Medicine
2021
Johns Hopkins University
2021
United States Naval Medical Research Unit SOUTH
2019-2021
University of Glasgow
2021
Instituto Nacional de Salud Pública
2019
National University of San Marcos
2019
Klebsiella variicola is considered an emerging pathogen in humans and has been described different environments. K. belongs to pneumoniae complex, which expanded the taxonomic classification hindered epidemiological evolutionary studies. The present work describes molecular epidemiology of based on MultiLocus Sequence Typing (MLST) developed for this purpose. In total, 226 genomes obtained from public data bases 28 isolates were evaluated, mainly humans, followed by plants, various animals,...
<h3>Objective</h3> To identify the clinical phenotypes and infectious triggers in 2019 Peruvian Guillain-Barré syndrome (GBS) outbreak. <h3>Methods</h3> We prospectively collected neurophysiologic data of patients with GBS admitted to a tertiary hospital Lima, Peru, between May August 2019. Molecular, immunologic, microbiological methods were used causative agents. Sera from 41 controls compared cases for antibodies <i>Campylobacter jejuni</i> gangliosides. Genomic analysis was performed on...
Campylobacter jejuni is a leading cause of diarrheal disease worldwide, and currently no preventative interventions are available. C. an invasive mucosal pathogen that has variety polysaccharide structures on its surface, including capsule. In phase 1 studies, capsule conjugate vaccine was safe but poorly immunogenic when delivered alone or with aluminum hydroxide. Here, we report enhanced immunogenicity the liposome adjuvants containing monophosphoryl lipid A without QS-21, known as ALF...
Abstract Background Campylobacter jejuni is a leading cause of bacterial diarrhea worldwide, and increasing rates fluoroquinolone (FQ) resistance in C. are major public health concern. The rapid detection tracking FQ critical needs developing countries, as these antimicrobials widely used against C . infections. Detection point mutations at T86I the gyrA gene by real-time polymerase chain reaction (RT-PCR) tool that may improve tracking. Methods isolates obtained from children with Peru were...
Campylobacter jejuni is the leading bacterial cause of diarrhea worldwide. A capsular polysaccharide (CPS) conjugate vaccine under development and requires determination valency. However, distribution CPS types circulating globally presently poorly described. We aimed to determine whether type in Peru differs from that other endemic regions. used a multiplex polymerase chain reaction (PCR) assay for detection encoding genes capable distinguishing all 35 on isolates two prospective...
In 2018/2019, two large Guillain–Barré Syndrome (GBS) outbreaks took place in Peru. Here, we report a comprehensive analysis of biological samples from GBS patients the 2019 outbreak. We applied metagenomic, microbiologic, and serological analyses to different collected patients. Further phenotypic genomic characterization was conducted on Campylobacter jejuni isolates samples. Microbiologic metagenomic revealed several with multiple co-infections, yet no common infectious agents were found...