A5101966018- Retinal Diseases and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Advanced Glycation End Products research
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Systemic Lupus Erythematosus Research
- Infectious Diseases and Tuberculosis
- Retinal and Optic Conditions
- Neurological Disorders and Treatments
- Otitis Media and Relapsing Polychondritis
- Protease and Inhibitor Mechanisms
- Blood Coagulation and Thrombosis Mechanisms
- Vasculitis and related conditions
- Proteoglycans and glycosaminoglycans research
- Cerebral Venous Sinus Thrombosis
- Immune cells in cancer
- Adolescent and Pediatric Healthcare
- Cell Adhesion Molecules Research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immune Response and Inflammation
- Pericarditis and Cardiac Tamponade
- Heme Oxygenase-1 and Carbon Monoxide
- Receptor Mechanisms and Signaling
- Cardiac Structural Anomalies and Repair
- Iron Metabolism and Disorders
Baylor College of Medicine
2023
WinnMed
2019
Mayo Clinic
2019
Wayne State University
2016
Institute of Post Graduate Medical Education and Research
2010-2014
Bose Institute
2014
Bose (United States)
2014
Institute of Ophthalmology
2013
New blood vessel formation in the retina because of prolonged hypoxia is believed to be directly associated with increased expression several growth factors and angiogenic cytokines. In present study, we made an attempt investigate possible association promoter polymorphisms interleukin 6, tumor necrosis factor α, 10 for pathogenesis proliferative diabetic retinopathy (PDR).This case-control study comprised 493 volunteers (253 PDR cases 240 controls). Cases controls were ascertained such...
Eales' disease (ED) is an idiopathic retinal vasculitis characterized by capillary nonperfusion and neovascularization. Previous reports on ED demonstrated that T-cell-mediated immunoresponse differential cytokine production in inflammatory angiogenic stage seem to influence the extent severity of this disease. Therefore, purpose study investigate gene polymorphisms occurrence ED.One hundred twenty-one patients with were recruited from Eastern Indian population compared 223 matched healthy...
In Brief Purpose: To evaluate erythrocyte redox state and its surrogates in patients with different stages of diabetic retinopathy their association cellular metabolic derangement developed retinal microvascular cells. Methods: Sixty type 2 nonproliferative (NPDR), 85 proliferative (PDR), 70 diabetes but without were considered as control (DC) for the study. addition, 65 normal individuals enrolled healthy this Erythrocyte oxidized nicotinamide adenine dinucleotide phosphate / reduced (NADP+...
Eales disease (ED) is an idiopathic, inflammatory, venoocclusive disorder of peripheral retina resulting in retinal angiogenesis and vitreous hemorrhage. The objective the present study to investigate expression activation gelatinase associated with neovascularization ED relation between levels cytokine tumor necrosis factor-α, known upregulate matrix metalloproteinase (MMP) on various cells.Vitreous serum samples from 19 patients who underwent surgery were estimated for MMP-2, MMP-9, tissue...
To identify the distribution, differential Toll-like receptor (TLR) expression, and functional contribution of monocyte subpopulations in inflammatory stage Eales' disease (ED).Peripheral blood mononuclear cells were isolated from nine patients during ED age- sex-matched healthy controls. The expression CD14, CD16, TLR-2, TLR-4 on monocytes was measured by flow cytometry. CD14⁺, CD16⁻, CD16⁺ populations sorted basis magnetic-activated cell-sorting methodology, levels cytokines ELISA.In...
ABSTRACT Conventional and molecular techniques were applied to detect characterize drug resistance of mycobacteria in the sputum samples clinically confirmed tuberculosis. The sensitivities mycobacterium detection by ZN staining, culture, multiplex PCR, restriction fragment length polymorphism (RFLP) 27.7%, 19.9%, 92.9%, 95.7%, respectively, but all 100% specific. conventional multiple-allele-specific PCR (MAS-PCR) methods enabled establishment 19.3% 86.9% cases, respectively. We...
ABSTRACT Background and Objectives Microcytic hypochromic anemia is the most common feature of alpha-thalassemia depends on number alpha genes deleted. Therefore, in this study, we aim to determine deletion mutations among microcytic cases West Bengal correlate them with different biochemical parameters endophenotypes. Methods Two hundred sixty patients were recruited. The GAP-PCR technique was adopted identify 3.7 kb 4.2 mutation HBA gene. Results Forty found have either or which represents...
INTRODUCTION:The primary cause of visual loss in the country like India are cataract, glaucoma, malnutrition, age related macular degeneration and diabetic retinopathy (DR) 1 .DR is most common microvascular complication both type 2 diabetes mellitus (DM) frequent single newly reported cases blindness among adults group 20 -75 years .Visual due to either develops from increased permeability retinal vessels (diabetic edema) or by proliferation new .Several angiogenic factors such as VEGF,...
19531 Background: Linolinamide is a well-established anti-angiogenic agent used extensively in relapsed & refractory multiple myeloma. The aim of our study was to evaluate the activity Thalidomide-dexamethasone combination patients symptomatic Myeloma as first line therapy and see toxicity Asian-Indian population. Materials Method: During period from July 2006 December 2007 we selected consecutive 24 haemato-oncology department Netaji Subhash Chandr Bose Cancer Research Institute. age range...