A5013921766- Organoboron and organosilicon chemistry
- Protein Kinase Regulation and GTPase Signaling
- Antifungal resistance and susceptibility
- Catalytic Cross-Coupling Reactions
- Click Chemistry and Applications
- Chemical synthesis and alkaloids
- Pneumonia and Respiratory Infections
- Chemical Synthesis and Reactions
- Synthesis and biological activity
- Phenothiazines and Benzothiazines Synthesis and Activities
- Chronic Lymphocytic Leukemia Research
- 14-3-3 protein interactions
- Bacterial biofilms and quorum sensing
- Sulfur-Based Synthesis Techniques
- Signaling Pathways in Disease
- Fungal Plant Pathogen Control
- Cellular transport and secretion
- Catalytic C–H Functionalization Methods
- Microbial Metabolism and Applications
- Synthesis and Biological Evaluation
- Cystic Fibrosis Research Advances
- Chronic Myeloid Leukemia Treatments
- Antibiotic Resistance in Bacteria
Université Claude Bernard Lyon 1
2020-2024
Laboratoire de Chémo-biologie synthétique et thérapeutique
2021
Normandie Université
2018
Institut National des Sciences Appliquées Rouen Normandie
2018
Université de Rouen Normandie
2018
Laboratoire COBRA
2018
The nitrosation of indoles under slightly acidic conditions and reverse addition leads to the preparation corresponding indazole-3-carboxaldehydes in high yields greatly minimizes side reactions.
A series of 4-membered sulfur-containing heterocycles was designed and evaluated for their ability to inhibit protein kinase DYRK1A, a target known have several potential therapeutic applications including cancers, Down syndrome or Alzheimer's disease.Our medicinal chemistry strategy relied on the design new compounds using ring contraction/isosteric replacement constrained analogy DYRK1A inhibitors, thus resulting in inhibitory activity enhancement.Whereas good effect targeted observed...
A series of sulfur-containing tetracycles was designed and evaluated for their ability to inhibit protein kinase DYRK1A, a target known have several potential therapeutic applications including cancers, Down syndrome or Alzheimer's disease. Our medicinal chemistry strategy relied on the design new compounds using ring contraction/isosteric replacement constrained analogy DYRK1A inhibitors, thus resulting in inhibitory activity enhancement. Whereas good effect targeted observed 5-hydroxy 4i-k (IC
This data article is related to a research paper entitled "Solvent- and metal-free hydroboration of alkynes under microwave irradiation" (Gioia et al. TETL-D-19-01698) [1]. Herein we present the spectral acquired from synthesis (E)-alkenyl boronic acid pinacol esters. The include general information synthetic procedure affording target derivatives, which were fully characterized by Nuclear Magnetic Resonance (1H 13C NMR) and, for most part, Electrospray Ionization High Resolution Mass...