A5089826010- Cardiac pacing and defibrillation studies
- Innovative Energy Harvesting Technologies
- Wireless Power Transfer Systems
- Neuroscience and Neural Engineering
- Energy Harvesting in Wireless Networks
- Cardiac Arrhythmias and Treatments
- solar cell performance optimization
- Advanced Battery Technologies Research
- Coronary Interventions and Diagnostics
- Advanced Sensor and Energy Harvesting Materials
- Fuel Cells and Related Materials
- Wireless Body Area Networks
- Advanced battery technologies research
- Chalcogenide Semiconductor Thin Films
- Neurological disorders and treatments
- Cardiac Imaging and Diagnostics
- Optical Coherence Tomography Applications
- Vascular Procedures and Complications
- Biomedical and Engineering Education
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Viral Infections and Immunology Research
- Advanced Fiber Laser Technologies
- Ocular and Laser Science Research
- Peripheral Artery Disease Management
University of Bern
2014-2024
University Hospital of Bern
2016-2024
University of Michigan
2016-2018
BACKGROUND Contemporary pacemakers (PMs) are powered by primary batteries with a limited energy-storing capacity.PM replacements because of battery depletion common and unpleasant bear the risk complications.Batteryless PMs that harvest energy inside body may overcome these limitations.OBJECTIVE The goal this study was to develop batteryless PM solar module converts transcutaneous light into electrical energy.METHODS Ex vivo measurements were performed modules placed under pig skin flaps...
Today's cardiac pacemakers are powered by batteries with limited energy capacity. As the battery's lifetime ends, pacemaker needs to be replaced. This surgical re-intervention is costly and bears risk of complications. Thus, a without primary desirable. The goal this study was test whether transcutaneous solar light could power pacemaker.We used three-step approach investigate feasibility sunlight-powered pacing. First, harvestable estimated. Theoretically, subcutaneously implanted 1 cm(2)...
Contemporary leadless pacemakers only feature single-chamber pacing capability. This study presents a prototype of dual-chamber pacemaker. Highly energy-efficient intrabody communication was implemented for wireless pacemaker synchronization. Optimal parameters were obtained by in vivo and ex measurements the heart blood. The successfully performed vivo. presented method may future also enable cardiac resynchronization therapy.
Active electronic implants are powered by primary batteries, which induces the necessity of implant replacement after battery depletion. This causes repeated interventions in a patients' life, bears risk complications and is costly. By using energy harvesting devices to power implant, device replacements may be avoided size reduced dramatically. Recently, several groups presented prototypes subcutaneous solar cells. However, data about expected real-life output subcutaneously implanted cells...
cardiac pacemakers require regular medical follow-ups to ensure proper functioning. However, device replacements due battery depletion are common and account for ∼25% of all implantation procedures. Furthermore, conventional pacemaker leads which prone fractures, dislocations or isolation defects. The ensuing surgical interventions increase risks the patients costs that need be avoided.in this study, we present a method harvest energy from endocardial heart motions. We developed novel...
Energy harvesting devices are widely discussed as an alternative power source for todays active implantable medical devices. Repeated battery replacement procedures can be avoided by extending the implants life span, which is goal of energy concepts. This reduces risk complications patient and may even reduce device size. The continuous powerful contractions a human heart ideally qualify substitute. In particular, in close proximity to such pacemakers, defibrillators or bio signal (ECG)...
Subdermal solar harvesting has the potential to obviate need for periodic battery replacements as required in patients with cardiac pacemakers. The achievable power output of subdermal module depends on implantation depth, optical skin properties and an important part cell characteristics. Monte Carlo simulations light distribution human were used estimate cells under midday sunlight exposure geographical mid-latitudes a function depth panel size. For darkest type, daily energy demand modern...
Life expectancy of contemporary cardiac pacemakers is limited due to the use an internal primary battery. Repeated device replacement interventions are necessary, which leads elevated risk for patients and increase health care costs. The aim our study investigate feasibility powering endocardial pacemaker by converting a minimal amount heart's kinetic energy into electric energy. intrinsic muscle activity makes it ideal candidate as continuous source pacemakers. For this reason, we developed...
Contemporary cardiac implantable electronic devices such as pacemakers or event recorders are powered by primary batteries. Device replacement due to battery depletion may cause complications and is costly. The goal of energy harvesting power the implant with from intracorporeal sources vibrations blood flow. By replacing batteries harvesters, reinterventions can be avoided size total device might reduced. This paper introduces a lever, which deflected stream within right ventricular outflow...
Eight commercially available percutaneous transluminal coronary angioplasty (PTCA), including semi-compliant and non-compliant balloons, have been assessed in detail on their tip, balloon, shaft, RX-Port, hypotube design. Important performance characteristics such as tip deformation, balloon elongation, deflation rate quantified.Five catheters of each model were evaluated during various tests. The robustness the tips was through compression, measuring any occurrence damage. longitudinal...
Cardiac pacemakers are powered by batteries, which become exhausted after a few years. This is problem in particular for leadless as they difficult to explant. Thus, autonomous devices energy harvesters desired.We developed an harvester endocardial implantation. The device contains microgenerator convert flexible turbine runner's rotation into electrical energy. runner driven the intracardiac blood flow; magnetic coupling allows hermetical sealing. has volume of 0.34 cm3 and weight 1.3 g....
Abstract Background Radiofrequency catheter ablation (RFA) is an effective treatment for atrial fibrillation. However, lesions are usually only assessed functionally. The immediate effect of RFA on the tissue not directly visualized. Optical coherence tomography (OCT) imaging technique that uses light to capture high‐resolution images with histology‐like quality. Therefore, it might be used high‐precision lesions. Methods and results ( n = 25) were produced freshly excised left right...
To treat stenosed coronary arteries, percutaneous transluminal angioplasty (PTCA) balloon catheters must combine pushability, trackability, crossability, and rewrap behavior. The existing anatomic track model (ASTM F2394) for catheter testing lacks 3D morphology, vessel tortuosity, compliance, making evaluating performance characteristics difficult. This study aimed to develop a three-dimensional patient-specific phantom (3DPSP) device safe training interventional cardiologists.
Abstract Background Percutaneous transluminal coronary angioplasty (PTCA) balloon catheters must withstand high pressures required for the lesion treatment, pushing loads during insertion, and pulling withdrawal. These pose a challenge especially polymeric tubular shafts with small cross sections. In order to enable new design innovations better understand mechanics of current catheter technologies, tensile properties polyamide (PA) 12 were investigated. PA dog bone specimens medical tubes...
Significance: Active implants require batteries as power supply. Their lifetime is limited and may a second surgical intervention for replacement. Intracorporal energy harvesting techniques generate within the body supply implant. Solar cells below skin can be used to harvest from light. Aim: To investigate potential of subdermal solar harvesting. Approach: We evaluated global radiation data defined time slots calculated output module based on cell characteristics. assumed exposure profiles...
Finite-element (FE) simulations that go beyond the linear elastic limit of materials can aid development polymeric products such as stretch blow molded angioplasty balloons. The FE model requires input an appropriate elastoplastic material model. Up to onset necking, identification hardening curve is well established. Subsequently, additional information cross-section and triaxial stress state inside specimen required. present study aims inversely identify post-necking behavior...
Background: Recently introduced leadless cardiac pacemakers effectively overcome all lead-related limitations of conventional pacemaker systems. However, these devices only feature single-chamber pacing capability although dual-chamber is highly desirable due to physiologic reasons. Implanting a into the right atrium and second one ventricle would enable dual chamber but requires wireless communication for device synchronization. Conventional radiofrequency telemetry not suitable this...
An autonomous energy source within a human body is of key importance in the development medical implants. This work deals with modelling and validation an harvesting device which converts myocardial contractions into electrical energy. The mechanism consists clockwork from commercially available wrist watch. We developed physical model able to predict total amount generated when applying external excitation. For model, custom-made hexapod robot was used accelerate along given trajectory....