A5066466055- Cardiac Health and Mental Health
- Heart Failure Treatment and Management
- Pediatric Pain Management Techniques
- Cardiovascular Function and Risk Factors
- Anesthesia and Pain Management
- Health Systems, Economic Evaluations, Quality of Life
- Pain Management and Opioid Use
- Stroke Rehabilitation and Recovery
- Cardiac Arrest and Resuscitation
- Biochemical Analysis and Sensing Techniques
- Nuclear Receptors and Signaling
- Musculoskeletal pain and rehabilitation
- Advanced Chemical Sensor Technologies
- Parkinson's Disease Mechanisms and Treatments
- Medication Adherence and Compliance
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular and exercise physiology
- Metabolomics and Mass Spectrometry Studies
Cambridge Cognition (United Kingdom)
2018-2021
Peninsula College of Medicine and Dentistry
2015-2016
University of Plymouth
2015-2016
Background Cardiac rehabilitation improves health-related quality of life (HRQoL) and reduces hospitalizations in patients with heart failure, but international uptake cardiac for failure remains low. Design methods The aim this multicentre randomized trial was to compare the REACH-HF (Rehabilitation EnAblement CHronicHeart Failure) intervention, a facilitated self-care home-based programme usual care adults reduced ejection fraction (HFrEF). study primary hypothesis that addition...
Introduction Home-based cardiac rehabilitation may overcome suboptimal rates of participation. The overarching aim this study was to assess the feasibility and acceptability novel Rehabilitation EnAblement in CHronic Hear Failure (REACH-HF) intervention for patients with heart failure preserved ejection fraction (HFpEF) their caregivers. Methods results Patients were randomised 1:1 REACH-HF plus usual care (intervention group) or alone (control group). is a home-based comprehensive...
Early detection of Alzheimer's disease (AD) will help researchers to better understand the and develop improved treatments. Recent developments have thus focused on identifying biomarkers for mild cognitive impairment due AD (MCI) during preclinical phase. The aim this pilot study is determine whether exhaled volatile organic compounds (VOCs) can be used as a non-invasive method distinguish controls from MCI, there are differences between MCI AD. gas chromatography—ion mobility spectrometry...
<b>Objective</b> To determine whether patient controlled analgesia (PCA) is better than routine care in patients presenting to emergency departments with moderate severe pain from traumatic injuries. <b>Design</b> Pragmatic, multicentre, parallel group, randomised trial. <b>Setting</b> Five English hospitals. <b>Participants</b> 200 adults (71% (n=142) male), aged 18 75 years, who presented the department requiring intravenous opioid for treatment of injuries and were expected be admitted...
Introduction The Rehabilitation EnAblement in CHronic Heart Failure (REACH-HF) trial is part of a research programme designed to develop and evaluate health professional facilitated, home-based, self-help rehabilitation intervention improve self-care health-related quality life people with heart failure their caregivers. will assess the clinical effectiveness cost-effectiveness REACH-HF patients systolic impact on outcomes Methods analysis A parallel two group randomised controlled 1:1...
Introduction The Rehabilitation EnAblement in CHronic Heart Failure patients with (HF) preserved ejection fraction (REACH-HFpEF) pilot trial is part of a research programme designed to develop and evaluate facilitated, home-based, self-help rehabilitation intervention improve self-care quality life (QoL) heart failure their caregivers. We will assess the feasibility definitive REACH-HF HFpEF impact on echocardiographic outcomes bloodborne biomarkers also be assessed. Methods analysis A...
<b>Objective</b> To determine whether patient controlled analgesia (PCA) is better than routine care in providing effective for patients presenting to emergency departments with moderate severe non-traumatic abdominal pain. <b>Design</b> Pragmatic, multicentre, parallel group, randomised trial <b>Setting</b> Five English hospitals. <b>Participants</b> 200 adults (66% (n=130) female), aged 18 75 years, who presented the department requiring intravenous opioid treatment of pain and were...
Background Rates of participation in centre (hospital)-cardiac rehabilitation by patients with heart failure are suboptimal. Heart has two main phenotypes differing underlying pathophysiology: reduced ejection fraction is characterised depressed left ventricular systolic function (‘reduced fraction’), whereas preserved diagnosed after excluding other causes dyspnoea normal fraction. This programme aimed to develop and evaluate a facilitated home-based cardiac intervention that could increase...
The effect of patient-controlled analgesia during the emergency phase care on prevalence persistent pain is unkown. We studied individuals with traumatic injuries or abdominal 6 months after hospital admission via department using an opportunistic observational study design. This was conducted postal questionnaires that were sent to participants recruited multi-centre solutions in setting study. Patients prior chronic states opioid use not studied. Questionnaires included EQ5D, Brief Pain...
Background Home-based models of cardiac rehabilitation may overcome suboptimal rates participation. Aim This study sought to assess the feasibility and acceptability a novel healthcare professional facilitated home-based comprehensive self-management REACH-HF intervention for patients with heart failure preserved ejection fraction (HFpEF) their caregivers. Method Patients were randomised 1 plus usual care (intervention group) or alone (control group). Outcomes collected at baseline, 3 6...
Objectives & Background The clinical effectiveness of patient controlled analgesia (PCA) has been demonstrated in a variety settings. However, PCA is rarely utilized the emergency department (ED). aim this study was to compare cost versus treatment as usual (TAU) patients admitted ward from ED with pain due traumatic injury or non-traumatic abdominal pain. This cost-effectiveness analysis previously reported PAin SoluTions In Emergency Setting (PASTIES) study. Methods Pain scores were...