A5049319310- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Cytomegalovirus and herpesvirus research
- Herpesvirus Infections and Treatments
- Infectious Diseases and Tuberculosis
- Diagnosis and treatment of tuberculosis
- Genomics and Phylogenetic Studies
- Parvovirus B19 Infection Studies
- Antibiotic Use and Resistance
- Mosquito-borne diseases and control
- Hematological disorders and diagnostics
- Respiratory viral infections research
- Antibiotic Resistance in Bacteria
- Urinary Tract Infections Management
- Infectious Diseases and Mycology
- Hepatitis B Virus Studies
- RNA and protein synthesis mechanisms
- Analytical Methods in Pharmaceuticals
- Ocular Infections and Treatments
- Bacillus and Francisella bacterial research
- Computational Drug Discovery Methods
- Immunodeficiency and Autoimmune Disorders
- Ocular Diseases and Behçet’s Syndrome
- Polyomavirus and related diseases
- Cancer therapeutics and mechanisms
University of Padua
1988-2022
Azienda Ospedaliera di Padova
2014-2020
Abstract BACKGROUND To evaluate the effect of chemotherapy on humoral immunity to vaccine‐preventable disease, authors investigated persistence protective antibody titers in a group patients who were alive and well after they treated for pediatric malignancies. METHODS Serum levels evaluated polio, tetanus, hepatitis B, rubella, mumps, measles 192 children. The terms lack loss , respectively, used describe absence tested only both before determined have chemotherapy. RESULTS Overall, serum...
Assessing cytomegalovirus (CMV)-specific cell-mediated immunity (CMI) represents an appealing strategy for identifying transplant recipients at risk of infection. In this study, we compared two gamma interferon-releasing assays (IGRAs), Quantiferon-CMV and CMV enzyme-linked immunosorbent spot (ELISPOT), to determine the ability each test predict protective CMV-specific T-cell responses. Two hundred twenty-one ELISPOT tests were conducted on 120 adult kidney (KTRs), including 100...
Immunological tests, including the QuantiFERON-TB Gold In-Tube (QFT-IT) assay, represent an important aid for diagnosing active tuberculosis (TB) and latent TB infections in children, but concerns about their use children <5 years of age persist. This is a multicenter retrospective study comparing population 226 to 521 adults with pulmonary or extrapulmonary TB.
ABSTRACT Human cytomegalovirus (CMV) infection is a major cause of congenital leading to birth defects and sensorineural anomalies, including deafness. Recently, cell-mediated immunity (CMI) in pregnant women has been shown correlate with CMV transmission. In this study, two interferon gamma release assays (IGRA), the enzyme-linked immunosorbent spot (ELISPOT) QuantiFERON assays, detecting CMV-specific CMI were compared. These performed for 80 CMV-infected (57 primarily 23 nonprimarily) 115...
One hundred and twenty-two Mycobacterium chimaera strains isolated in Italy from cardiac surgery-related patients, surgery-unrelated patients heater-cooler units, were submitted to whole-genome sequencing subsequent SNP analysis. All but one belonged Subgroup 1.1 (19/23) or 1.8 (3/23). Only 28 out of 79 units groupings other than 1.8. The instead distributed across the phylogenetic tree. Our data, first on isolates Italy, are agreement with a recent large genomic study suggesting common...
Gamma interferon release assays were recently introduced in health care worker (HCWs) screenings for tuberculosis surveillance. In longitudinal surveys, conversions and reversions are seen, yet whether these changes unspecific or an expression of new infections microbial clearance remains unclear. order to further elucidate changes, we analyzed outbreak 15 transient 53 HCWs who operate the same laboratory handle specimens potentially containing Mycobacterium underwent screening by...
Mycobacterium abscessus complex, hereinafter Mab, is a taxonomic group of rapidly growing, nontuberculous mycobacteria (NTM). Despite major advances in understanding virulence, pathogenicity and mechanism antibiotic resistance, Mab remains significant cause pulmonary extra-pulmonary disease. Herein, we describe disseminated, macrolide-resistant, subspecies infection occurring severely immune-compromised 34-year-old allotransplanted female patient affected by chronic graft versus host disease...
Abstract One hundred and twenty-two Mycobacterium chimaera strains isolated in Italy from cardiac surgery-related patients, surgery-unrelated patients heater-cooler units, were submitted to whole-genome sequencing subsequent SNP analysis. All but one belonged Subgroup 1.1 (19/23) or 1.8 (3/23). Only 28 out of 79 units groupings other than 1.8. The instead distributed across the phylogenetic tree. Our data, first on isolates Italy, are agreement with a recent large genomic study suggesting...