- Pharmacogenetics and Drug Metabolism
- Atherosclerosis and Cardiovascular Diseases
- Traditional Chinese Medicine Analysis
- Peroxisome Proliferator-Activated Receptors
- RNA modifications and cancer
- Cholesterol and Lipid Metabolism
- Psidium guajava Extracts and Applications
- Autophagy in Disease and Therapy
- Traditional Chinese Medicine Studies
- Pharmacology and Obesity Treatment
- Drug Transport and Resistance Mechanisms
- Bone Metabolism and Diseases
- Eicosanoids and Hypertension Pharmacology
- Healthcare and Venom Research
- Complementary and Alternative Medicine Studies
- Fuel Cells and Related Materials
- Computational Drug Discovery Methods
- Phytochemical Studies and Bioactivities
- Analytical Chemistry and Chromatography
Shuguang Hospital
2021-2025
Shanghai University of Traditional Chinese Medicine
2021-2025
PharmacoGenetics (China)
2007
Central South University
2007
Myocardial ischemia/reperfusion injury (MIRI) poses a formidable challenge to cardiac reperfusion therapy due the absence of effective clinical interventions. Methylation N6-methyladenosine (m6A), which is most common post-transcriptional modifications occurring within mammalian mRNA, believed be involved in MIRI by modulating autophagy. MicroRNAs (miRNAs) play crucial role regulating gene expression at level and have been implicated regulation m6A methylation. Suxiao Jiuxin Pill (SJP)...
Objective This study aimed to explore the regulatory effects of aerobic exercise on RANKL/RANK/OPG signaling pathway and evaluate its potential therapeutic osteoporosis in ovariectomized mice (OVX).Methods:1.Animal Experiment: 40 2-month-old SPF male SD rats, weighing (225±25) g, were purchased from Animal Experiment Center Xi’an Jiaotong University (Qualification Certificate No.: Shaanxi Medical Practice No. 17). The experiment was conducted at Experimental Yan’an College. Rats had free...
Dunyeguanxinning (DYGXN) has been shown to have therapeutic effects in preventing and treating atherosclerosis. However, the active components anti- atherosclerosis (AS) mechanisms of DYGXN remain be elucidated. This study aims explore functional prevention treatment (AS). The were identified using UPLC-Q-Orbitrap HRMS technology. Network pharmacology molecular docking utilized core targets DYGXN. An AS mouse model was established verify results obtained from network pharmacology. A total 20...