A5029112933- Obesity, Physical Activity, Diet
- Eating Disorders and Behaviors
- Obesity and Health Practices
- Regulation of Appetite and Obesity
- Growth Hormone and Insulin-like Growth Factors
- Stress Responses and Cortisol
- Diabetes Management and Research
- Spaceflight effects on biology
- Diabetes Management and Education
- Mindfulness and Compassion Interventions
- Asthma and respiratory diseases
- Infant Development and Preterm Care
- HIV-related health complications and treatments
- Metabolism, Diabetes, and Cancer
- HIV/AIDS drug development and treatment
- Health and Lifestyle Studies
- Diabetes Treatment and Management
- Lipid metabolism and disorders
- Sleep and related disorders
- Pharmaceutical studies and practices
- Thyroid Disorders and Treatments
- Birth, Development, and Health
- Nutritional Studies and Diet
- Ovarian function and disorders
- Child Nutrition and Feeding Issues
Kings County Hospital Center
2020
United States Food and Drug Administration
2020
Elmhurst Hospital Center
2020
Mount Sinai Queens
2020
Queens Hospital Center
2020
State University of New York
2012-2020
Icahn School of Medicine at Mount Sinai
2020
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2015-2019
National Institutes of Health
2015-2019
United States Department of Health and Human Services
2016
In early 2020, the FDA requested that manufacturer of lorcaserin voluntarily withdraw drug from market because a signal increased cancer risk. The concluded drug's benefits don't outweigh its risks for any identifiable patient population.
Summary Background Youths with overweight and obesity report frequent instances of weight‐based teasing. However, little is known about the prospective associations between teasing changes in body composition among youth. Objective To assess mass index (BMI) fat a longitudinal study youths with, or at‐risk for, obesity. Methods One hundred ten participated observational study. The Perception Teasing Scale was administered at baseline. Height, weight, were obtained baseline follow‐ups (range:...
ABSTRACT Objective Adolescent emotional‐eating, referring to eating in response negative affective states, is frequently reported by those with loss of control (LOC) eating. Although LOC has been shown predict exacerbated disordered and excess weight/adiposity gain, the extent which either alone or combination LOC, predicts adverse outcomes not determined. Thus, we examined associations baseline emotional‐eating changes eating, BMI, adiposity over 1‐year, what degree presence absence...
Objective To examine the associations among self-reported loss-of-control (LOC) eating, emotion dysregulation, body mass, and objective energy intake youth. Emotion dysregulation may be 1 individual factor that promotes excess increases in mass youth with LOC eating. Method Children adolescents (N = 230; 8 to 17 years) enrolled a nonintervention study completed structured interview determine presence or absence of Children's was assessed via parent-report Child Behavior Checklist. Youth also...
Background . Blood pressure (BP) percentiles in childhood are assessed according to age, gender, and height. Objective To create a simple BP/height ratio for both systolic BP (SBP) diastolic (DBP). study the relationship between ratios corresponding children. Methods We analyzed data on height from 2006-2007 NHANES data. were calculated 3775 Receiver-operating characteristic (ROC) curve analyses performed calculate sensitivity specificity of as diagnostic tests elevated (>90%)....
Loss of control (LOC) eating in youth is associated with excess body weight and adiposity. After adjusting for fat mass, LOC have higher blood pressure low-density lipoprotein cholesterol compared to without eating. Increased inflammation may account this relationship, although few data examined hypothesis. Therefore, study explored the association between high-sensitivity C-reactive protein (hsCRP), a marker inflammation.We investigated hsCRP concentrations relation convenience sample 194...
In adults, obesity is associated with abnormalities of thyroid function; there are fewer studies in paediatric cohorts.To examine associations weight and adiposity indices function thyroid-related metabolic factors children.A sample 1203 children without (body mass index [BMI] < 95th percentile; N = 631) (BMI ≥ 572), age 5-18 years, had height measured (to calculate BMI-Z score for sex) blood collected the morning thyroid-stimulating hormone (TSH), free thyroxine (FT4) leptin. A subset (N...
Prospective data suggest depressive symptoms worsen insulin resistance and accelerate type 2 diabetes (T2D) onset.We sought to determine whether reducing in overweight/obese adolescents at risk for T2D would increase sensitivity mitigate risk.We conducted a parallel-group, randomized controlled trial comparing 6-week cognitive-behavioral (CB) depression prevention group with health education (HE) control 119 adolescent girls mild-to-moderate (Center Epidemiological Studies-Depression Scale...
Objective Eating in the absence of hunger (EAH) refers to consumption palatable foods a sated state. It has been proposed that EAH promotes excess weight gain youth; yet there are limited prospective data support this hypothesis. We examined whether at baseline predicted increases body mass (BMI and BMIz) fat (kg) 1 year later among adolescent boys girls. Methods was assessed as adolescents' snack following eating satiety from an ad libitum lunch buffet. Parents also completed questionnaire...
Background. Underlying insulin resistance and/or obesity has clearly been implicated in the development of metabolic syndrome adolescents and young adults with polycystic ovarian (PCOS). It is not clear however what role hyperandrogenism on or its those parameters associated syndrome. Methods. We studied 107 adolescent girls; 54 had PCOS according to NIH criteria. Data was obtained for systolic diastolic blood pressure (SBP DBP), body mass index (BMI), total testosterone (T), luteinizing...
Children with obesity have low spontaneous growth hormone (GH) secretion. High circulating free fatty acid (FFA) concentration is believed to inhibit GH secretion in those obesity. In adults, lipolytic inhibition niacin lowers FFA and increases GH, but there are no prior studies children obesity.The objective of the study was determine dose frequency administration required lower stimulate obesity.Dose-finding nondiabetic ages 6-12 years body mass index (BMI) ≥ 95th percentile given 250 mg...
The aim of this study is to elucidate factors that may influence paternal attachment preterm infants in an urban hospital setting. Fathers admitted a level III neonatal intensive care unit (NICU) were eligible for study. Paternal Postnatal Attachment Scale (PPAS) questionnaire invokes five domains: patience, tolerance, pleasure, affection and pride. Clinical demographic data collected along with the PPAS identify influencing attachment. Infants studied 28.1 ± 3.3 weeks gestational age birth...
Adults with binge eating disorder may have an exaggerated or blunted cortisol response to stress. Yet, limited data exist among youth who report loss of control (LOC) eating, a developmental precursor disorder.We studied reactivity 178 healthy adolescents and without LOC eating. Following buffet lunch meal were randomly assigned watch neutral sad film clip. After, they offered snacks from multi-item array assess in the absence hunger. Salivary was collected at -80, 0, 30 50 min relative...
<b><i>Background/Aims:</i></b> Animal studies suggest that leptin may adversely affect bone mineral density (BMD). Clinical have yielded conflicting results. We therefore investigated associations between and parameters in children. <b><i>Methods:</i></b> 830 healthy children (age = 11.4 ± 3.1 years; 75% female; BMI standard deviation score [BMIz] 1.5 1.1) had fasting serum measured with ELISA body composition by dual-energy X-ray...
Few studies have characterized the relation between parent’s depression symptoms and adolescent’s in adolescents at-risk for type 2 diabetes (T2D). We evaluated associations of parental with metabolic functioning adolescent offspring T2D. One-hundred sixteen parents girls a family history completed surveys symptoms. Adolescents’ degree risk T2D was estimated from body mass index (BMI; kg/m2) standard score, percent adiposity dual-energy x-ray absorptiometry scan, whole insulin sensitivity...