A5032230958- Air Quality and Health Impacts
- Amyotrophic Lateral Sclerosis Research
- Climate Change and Health Impacts
- Environmental Justice and Health Disparities
- Health, Environment, Cognitive Aging
- Urban Transport and Accessibility
- COVID-19 impact on air quality
- COVID-19 epidemiological studies
- Statistical Methods and Bayesian Inference
- Autism Spectrum Disorder Research
- Air Quality Monitoring and Forecasting
- Pesticide Exposure and Toxicity
- Genetics and Neurodevelopmental Disorders
- COVID-19 Pandemic Impacts
- Environmental and Social Impact Assessments
- Urinary and Genital Oncology Studies
- Paraoxonase enzyme and polymorphisms
- Gallbladder and Bile Duct Disorders
- Data Analysis with R
- Telomeres, Telomerase, and Senescence
- Risk Perception and Management
- Fungal Infections and Studies
- Pluripotent Stem Cells Research
- Cholinesterase and Neurodegenerative Diseases
- Environmental Education and Sustainability
Columbia University
2017-2024
Healthy Start
2024
Rady Children's Hospital-San Diego
2014-2016
University of California, San Diego
2014-2016
Over the last decades, air pollution emissions have decreased substantially; however, inequities in persist. We evaluate county-level racial/ethnic and socioeconomic disparities changes from six source sectors (industry [SO
Numerous methods exist to analyze complex environmental mixtures in health studies. As an illustration of the different uses mixture methods, we employed geared toward distinct research questions concerning persistent organic chemicals (POPs) as a and leukocyte telomere length (LTL) outcome. With information on 18 POPs LTL among 1,003 U.S. adults (NHANES, 2001–2002), used unsupervised including clustering identify profiles similarly exposed participants, Principal Component Analysis (PCA)...
BACKGROUND: Adult-onset neurodegenerative diseases affect millions and negatively impact health care systems worldwide.Evidence suggests that air pollution may contribute to aggravation of neurodegeneration, but studies have been limited.OBJECTIVE: We examined the potential association between long-term exposure particulate matter ≤2:5 lm in aerodynamic diameter [fine (PM 2:5 )] disease Alzheimer's (AD) Parkinson's (PD) amyotrophic lateral sclerosis (ALS), using first hospitalization as a...
To mitigate the COVID-19 pandemic and prevent overwhelming healthcare system, social-distancing policies such as school closure, stay-at-home orders, indoor dining closure have been utilized worldwide. These function by reducing rate of close contact within populations result in decreased human mobility. Adherence to social distancing can substantially reduce disease spread. Thus, quantifying mobility compliance, especially at high temporal resolution, provide great insight into impact...
Background: Environmental health researchers often aim to identify sources or behaviors that give rise potentially harmful environmental exposures. Objective: We adapted principal component pursuit (PCP)—a robust and well-established technique for dimensionality reduction in computer vision signal processing—to patterns mixtures. PCP decomposes the exposure mixture into a low-rank matrix containing consistent of across pollutants sparse isolating unique extreme events. Methods: accommodate...
The negative impacts of global climate change are well-known, but the health benefits mitigation actions and their high monetary valuations less appreciated. Actions to reduce use fossil fuels greenhouse gas (GHG) emissions from energy production, industry, transportation, agriculture will also bring major public (see Figure 1).1 Economic care savings improved population can far exceed cost measures. Cities, regions, countries that implement gain immediate long-term economic these...
Abstract Studies suggest a link between particulate matter less than or equal to 2.5 μm in diameter (PM2.5) and amyotrophic lateral sclerosis (ALS), but our knowledge critical exposure windows have not been examined. We performed case-control study the Danish population spanning years 1989–2013. Cases were selected from National Patient Registry based on International Classification of Diseases codes. Five controls randomly Civil matched case vital status, age, sex. PM2.5 concentration at...
Long-term exposure to fine particulate matter (PM2.5) has been associated with disease aggravation in amyotrophic lateral sclerosis (ALS). In this study, we characterized long-term six major PM2.5 components and their individual association ALS.We leveraged 15 years of data from the New York Department Health Statewide Planning Research Cooperative System (2000-2014) calculate annual ALS first hospitalizations State. We used hospital admission as a surrogate prediction model estimate...
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. Limited evidence suggests ALS diagnosis may be associated with air pollution exposure and specifically traffic-related pollutants.
The association between fine particulate matter (PM2.5) and cardiovascular outcomes is well established. To evaluate whether source-specific PM2.5 differentially associated with disease in New York City (NYC), we identified sources examined the exposure risk of hospitalization for myocardial infarction (MI).We adapted principal component pursuit (PCP), a dimensionality-reduction technique previously used computer vision, as novel pattern recognition method environmental mixtures to apportion...
Statistical learning includes methods that extract knowledge from complex data. beyond generalized linear models, such as shrinkage or kernel smoothing methods, are being increasingly implemented in public health research and epidemiology because they can perform better instances with high-dimensional data-settings which traditional statistical fail. These novel however, often include random sampling may induce variability results. Best practices data science help to ensure robustness. As a...
BACKGROUND AND AIM: To mitigate the COVID-19 pandemic and prevent overwhelming healthcare system, social-distancing policies such as school closure, stay-at-home orders, indoor dining closure have been utilized worldwide. These function by reducing rate of close contact within populations results in decreased human mobility. Adherence to social distancing can substantially reduce disease spread. Thus, quantifying mobility compliance, especially at high temporal resolution, provide great...
OPS 21: Methodological progress in chemicals health effects research, Room 210, Floor 2, August 26, 2019, 4:30 PM - 5:30 Background. Multiple methods exist to analyze environmental mixtures studies. To illustrate the differences among based on research question each answer, we employed geared toward distinct questions a sample concerning persistent organic pollutants (POPs) as mixture and leukocyte telomere length (LTL) an outcome. Methods. With information 18 POPs LTL 1,003 U.S. adults...