A5102017385- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Tryptophan and brain disorders
- Mental Health Treatment and Access
- Child and Adolescent Psychosocial and Emotional Development
- Attention Deficit Hyperactivity Disorder
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Mental Health Research Topics
- Streptococcal Infections and Treatments
- Mental Health and Psychiatry
- Functional Brain Connectivity Studies
- Autism Spectrum Disorder Research
- Neural and Behavioral Psychology Studies
- Adolescent and Pediatric Healthcare
- Genetics and Neurodevelopmental Disorders
- Maternal and Neonatal Healthcare
- Obsessive-Compulsive Spectrum Disorders
- Advanced Neuroimaging Techniques and Applications
- Healthcare professionals’ stress and burnout
- Urological Disorders and Treatments
- Sexuality, Behavior, and Technology
- Child and Adolescent Health
- Perfectionism, Procrastination, Anxiety Studies
- Psychology and Mental Health
- Suicide and Self-Harm Studies
University of Coimbra
2015-2024
Hospitais da Universidade de Coimbra
2013-2024
Clinical Academic Center of Braga
2022
Centro Hospitalar do Baixo Vouga
2021
Hospital Clínico Universitario de Valladolid
2020
University of Algarve
2010
Introdução: A perturbação de hiperatividade e défice atenção (PHDA) é uma das patologias neuropsiquiátricas mais comuns, afetando cerca 2%‑4% da população adulta. intervenção farmacoterapêutica primeira linha são os psicoestimulantes como o metilfenidato as anfetaminas. Geralmente, terapêutica farmacológica segunda utilizada quando há ineficácia, intolerância ou contraindicação para uso estimulantes. Métodos: Estudo retrospetivo observacional dos doentes seguidos na Consulta...
Abstract Background Deficits in executive function (EF) are consistently reported autism spectrum disorders (ASD). Tailored cognitive training tools, such as neurofeedback, focused on enhancement might have a significant impact the daily life functioning of individuals with ASD. We report first real-time fMRI neurofeedback (rt-fMRI NF) study targeting left dorsolateral prefrontal cortex (DLPFC) Methods Thirteen without intellectual disability and seventeen neurotypical completed rt-fMRI...
Executive functions and motivation have been established as key aspects for neurofeedback success. However, task-specific influence of cognitive strategies is scarcely explored. In this study, we test the ability to modulate dorsolateral prefrontal cortex, a strong candidate clinical application in several disorders with dysexecutive syndrome, investigate how feedback contributes better performance single session. Participants both (n = 17) sham-control 10) groups were able DLPFC most runs...
Introduction: Recently, university counseling services have been faced with an increasing number of students seeking psychological support. However, human resources and time constraints limit the to respond adequately. national guidelines for Mental Health Services in Higher Education recommended stepped care approach increase efficiency. The present study aimed explore implementation a model Portuguese public university, analyzing students’ sociodemographic clinical characteristics,...
Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) is a crucial component of the cellular machinery responsible for homeostasis. The selective inhibition SERCA by thapsigargin (TG) leads to perturbations in signaling, which can trigger endoplasmic (ER) stress. unfolded protein response (UPR) pathway activated ER stress and induces an adaptive preserve cell survival or committee cells programmed death, depending on duration and/or level. Early stages stimulate mitochondrial metabolism but under...
Introduction: Illness behaviour and Help-Seeking can have great impact on patient's health quality of life; therefore, it's important to an appropriate scale assess these constructs.Objectives: To study the psychometric qualities IHSBS Portuguese mental patients, its reliability, construct concurrent validity, measured using Stigma Scale (SS).Methods: The sample comprised 140 with different psychiatric diagnosis (70% women), mean age 39.49 years old (SD=15.71;V=18-78), followed in centers...
This study aims to evaluate whether mitochondrial changes occur in the early stages of bipolar disorder (BD). Using fibroblasts derived from BD patients and matched controls, levels proteins involved biogenesis dynamics (fission fusion) were evaluated by Western Blot analysis. Mitochondrial membrane potential (MMP) was studied using fluorescent probe TMRE. morphology analyzed with Mitotracker Green mitophagy quantifying co-localization HSP60 (mitochondria marker) LC3B (autophagosome...
The profile of executive function (EF) in adults with Schizophrenia (SCZ) and autism spectrum disorder (ASD) remains unclear. This study aims to ascertain if distinct EF patterns can be identified between each clinical condition by comparing the neuropsychological SCZ ASD, for whom differential diagnosis is still highly challenging. Forty-five individuals (15 SCZ, 15 controls) matched age, sex, education level, handedness underwent intelligence evaluation testing working memory, inhibition,...
Neonatal lupus erythematosus is a rare, passively acquired autoimmune disease, caused by maternal autoantibodies. The most common manifestations are skin rash and congenital heart block. Cutaneous may be present at birth, but often develop within few weeks after delivery. Congenital block as bradycardia in utero or during physical examination birth. Approximately 40–60% of mothers asymptomatic when the infants diagnosed. We case child, born with lesions face, scalp, trunk, limbs...
Introduction In recent years, researchers and clinicians have shown an increasing interest in self-compassion. Indeed, several studies suggested that self-compassion is a positive factor for mental physical health. The Self-Compassion Scale (SCS; Neff, 2003) has been widely used to assess six dimensions of (self-kindness, self-judgment, common humanity, isolation, mindfulness over-identification) among diverse populations. Recently, it also perinatal samples but its psychometric properties...
Schizophrenia-spectrum disorders (SSD) are characterized by impaired emotion processing and attention. SSD patients more sensitive to the presence of emotional distractors. But despite growing interest on emotion-attention interplay, interference in is far from fully understood. Moreover, research date has not established link between attentional control SSD. This study thus aimed investigate effects facial expression SSD, manipulating perceptual load.Twenty-two 22 healthy controls performed...
Neonatal meningitis is a serious disease with significant mortality and morbidity. Its signs symptoms are subtle, non-specific, atypical or absent. Cephalohaematoma frequent in newborns complications uncommon, including local infection after haematogenous spread the setting of bacteraemia possibility osteomyelitis, epidural abscess subdural empyema. We report case late preterm newborn, an unremarkable pregnancy, born by vacuum-assisted vaginal delivery that presented fifth day life...
Background Metastatic tumours sometimes present with neuropsychiatric symptoms, however psychiatric symptoms as rarely the first clinical manifestation. Cutaneous melanoma is third most common cause of brain metastasis, known risk factors increasing chance such central nervous system metastization. Objectives We a report delirium manifestation metastases, illustrating relevance an adequate and early differential diagnosis. Methods In addition to describing case, searches were undertaken in...
Introduction The term burn-out or burnout, means 'burn to exhaustion', this was first used by Herbert Freundenberg. According Freundenberg, burnout is a 'state of physical and mental exhaustion conditioned the individual's professional activity'. That manifested through set signs symptoms associated with emotional breakdown that result from total energy lack resources forces 'help' others.Objectives Assess occurrence in Portuguese gastroenterologists understand how certain sociodemographic...
Abstract Aim Patients in early phases of schizophrenia or mood disorders with psychotic symptoms have a wide array metabolic abnormalities. We analysed the potential predictive value uric acid (UA) levels and other parameters first‐episode psychosis patients to differentiate between non‐affective affective psychosis. Methods Retrospective chart review all referenced unit ( n = 149), 2012 2017, available UA levels. included 37) were compared according follow‐up diagnosis disorder. Results...
The prevalence of autism spectrum disorders (ASD) is increasing, and the correlates involvement this population in criminal justice system have been reported. People with ASD specific deficits such as difficulties social communication behavior, impulsivity, misinterpretation rules, obsessions, restricted interests, increasing their vulnerability to becoming victims offenders. Herein, we report case a male 40 high-functioning patient accused stalking. This paper highlights clinical forensic...
Innate vulnerabilities in autism spectrum disorder (ASD) could increase the risk of comorbid psychiatric conditions and judicial problems. Persistent deficits social communication, narrow, repetitive interests, or sensory impairments lead to deviant behaviors. This case study refers a 22-year-old male who exhibited behavioral particularities agreement with presence frotteurism kleptomania. The impulsive nature these behaviors was consistent stereotyped patterns. Premorbid impairments, mainly...