Aimed at efficient production of 5-hydroxymethylfurfural (HMF) in a green and sustainable way, dehydrogenation fructose was enhanced by liquid–liquid extraction membrane dispersion microreactor. On account the high mass-transfer rate resulted from dripping flow, obtained HMF readily extracted aqueous phase to organic phase, effectively preventing sequence side reaction leading selectivity. Enhanced extraction, duration decreased 60 min traditional stirred reactor 4 microreactor, an increase...

Microbubbles have gained universal interest due to their wide applications in water treatment, cosmetics, and pharmaceutical industry potential gas–liquid reactions such as hydrogenation oxidation. However, microbubble formation organic solvents has been seldom investigated. A controllable efficient platform is built investigate using a hydrophilic ceramic membrane hydrophobic polytetrafluoroethylene (PTFE) membrane. The effect of wettability on the size microbubbles studied with change...

Abstract Microbubble column reactors (MBCRs) have the significant advantages of high gas holdup, large gas‐liquid interfacial area, and excellent mass transfer performance, making them attractive for applications such as hydrogenation oxidation. However, there is still a lack comprehensive understanding flow behavior in MBCRs. In this work, effects liquid superficial velocities on regimes, residence time distribution, holdup are investigated. The increases linearly with increase velocity,...

Using the precipitation method, we propose a new process for preparation of high specific surface area and large pore volume ZnO nanoparticles in unconfined space with NH4HCO3 ZnSO4·7H2O as reactants. The mixing performance reaction system was improved by gas atomization continuous gas-based impinging streams before reaction. By virtue environment division, obtained have very good dispersion performance. Under optimal conditions, were synthesized 88.89 m2/g, an average diameter 7 nm, 0.68...

Background: Colorectal cancer (CRC) has few or no symptoms and is often diagnosed at its end stage. Boeravinone B (BB) a natural rotenoid which induces an antioxidative effect been used in prevention. In this study, we scrutinized the chemoprotective of BB against 1,2dimethyl hydrazine (DMH) induced CRC rats. Methods: Subcutaneous administration DMH (40 mg/kg) was for induction rats, followed by oral BB. The body weight, tumor volume, incidence, total number tumors were estimated all rat...

A flexible on-demand cell-free protein synthesis platform using a tube-in-tube reactor is established for continuous of different drugs.

Involved in most aerobic biochemical processes, oxygen affects cellular functions, and organism behaviors. Protein synthesis, as the underlying biological process, is unavoidably affected by regulation of delivery utilization. Bypassing cell wall, cell-free protein synthesis (CFPS) systems are well adopted for precise analysis bioprocesses. Here a reliable flow platform was developed measuring analyzing on processes combining Escherichia coli-based CFPS tube-in-tube reactor. This allows...

The inflammatory indexes are attracting increasing attention as a prognostic predictor for colorectal cancer (CRC). However, the value of preoperative lymphocyte-to-C-reactive protein ratio (LCR) in patients with non-metastatic CRC remains to be established.A total 955 from 2010 2014 at single center were included. Receiver operating characteristic curves (ROC) generated define optimal cutoff indexes, and areas under curve (AUC) calculated compare predictive among indexes. Fine Gray...

Here, we present a strategy for rapid measurement of gas solubility in ionic liquids based on simple configuration tube-in-tube reactor. Ionic can be rapidly saturated without direct contact and liquid via semipermeable Teflon AF-2400 inner tubing the reactor, easily determined by steady-state flux balance both flowing into Solubility data gaseous carbon dioxide (CO2), ethylene (C2H4), ethane (C2H6) several ([Emim][NTf2], [Omim][NTf2], [Bmim][BF4], [Bmim][PF6], [Omim][NTf2]) were...

Along with the occurrence of cisplatin resistance, treatment on gastric cancer (GC) becomes difficult. Therefore, researches new therapeutic methods to revert resistance are becoming increasingly urgent. qRT-PCR was used quantify expression miR-4486, JAK3 in SGC-7901 or SGC-7901/DDP cell lines. WB utilized analyze JAK3, STAT3 and p-STAT3 CCK-8 assay determine IC50 both lines viability The target relationship between miR-4486 determined by luciferase assay. MiR-4486 apoptosis flow cytometry....

The increased mortality of gastric cancer (GC) is mainly attributed to the development chemoresistance. Circular RNAs, as novel type biomarkers in GC, have attracted wide attention. purpose this study was investigate functional role circ_0081143 GC with doxorubicin (DR) resistance and its potential action mechanism.The expression circ_0081143, miR-129-2-3p YES proto-oncogene 1 (YES1) tissues cells measured by quantitative real-time polymerase chain reaction. half maximal inhibitory...

Counter-current operation has been widely applied to enhance the extraction efficiency for systems with low distribution coefficients, which was hindered in microextraction because viscous force and surface tension dominate over gravity inertial force. In this study, a novel design of tube-in-tube microextractor relying on poly tetra fluoroethylene membrane construct stable interface proposed conduct continuous counter-current extraction. Extraction kinetics two different membranes pore...

Background: To summarise data from previous reports and perform a meta-analysis to compare the short-term surgical outcomes post-operative recovery between single-incision multi-port laparoscopic distal gastrectomy (MLDG) for gastric cancer. Methods: A systematic literature search was performed using PubMed Embase databases relevant were extracted. Short-term of (SLDG) MLDG cancer compared fixed or random-effect model. Results: In total, we identified five studies involving 983 participants...

Abstract In this work, an unsteady‐state strategy for rapid measurement of gas diffusivity in liquid is proposed, which has a quick perturbation the flow rate inner tube obtaining change across membrane with time. The taken full advantages tube‐in‐tube reactor that possesses high permeability Teflon AF‐2400 to accelerate diffusion without direct contact between two phases. With developed mathematical model fitting recorded variation time, can be determined within 0.5–3 min compared...