A5074464858- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Connective tissue disorders research
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Cardiovascular Issues in Pregnancy
- Hip disorders and treatments
- Complement system in diseases
- Infectious Aortic and Vascular Conditions
- Pulmonary Hypertension Research and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Colorectal Cancer Surgical Treatments
- Congenital Heart Disease Studies
- Mechanical Circulatory Support Devices
- Neurogenetic and Muscular Disorders Research
- Glaucoma and retinal disorders
- Cancer Treatment and Pharmacology
- Cardiac Structural Anomalies and Repair
- Venous Thromboembolism Diagnosis and Management
- Clinical Nutrition and Gastroenterology
- Renal Diseases and Glomerulopathies
- Blood Coagulation and Thrombosis Mechanisms
- Intensive Care Unit Cognitive Disorders
- Vascular anomalies and interventions
Oslo University Hospital
2018-2024
Kungälvs Sjukhus
1998
While serum-circulating complement destroys invading pathogens, intracellularly active complement, termed the “complosome,” functions as a vital orchestrator of cell-metabolic events underlying T cell effector responses. Whether intracellular is also nonredundant for activity myeloid immune cells currently unknown. Here, we show that monocytes and macrophages constitutively express component (C) 5 generate autocrine C5a via formation an C5 convertase. Cholesterol crystal sensing by induced...
Background and Purpose- A significant proportion of ischemic strokes are caused by emboli from unstable carotid artery plaques with intraplaque neovascularization (IPN) as a key feature plaque instability. IPN is not detectable conventional Doppler ultrasound. Contrast-enhanced ultrasound (CEUS) can visualize IPN, but its use limited in clinical practice because it requires an intravenous injection contrast. Superb microvascular imaging (SMI) without contrast uses algorithm to remove clutter...
Abstract Aims We aimed to assess the prevalence of mitral annulus disjunction (MAD) and explore association with aortic disease valve surgery in patients Marfan syndrome (MFS) Loeys–Dietz (LDS). Methods results included consecutive MFS fulfilling Revised Ghent Criteria LDS Nosology. MAD was identified by echocardiography quantified as longitudinal distance from ventricular myocardium hinge point posterior leaflet. Aortic events were defined dissection or prophylactic surgery. recorded need...
Abstract Background Contemporary management of uncomplicated type B aortic dissections (uTBAD) is based on the acuity and various morphological features. Medical therapy mandatory, while risks early thoracic endovascular repair (TEVAR) are balanced against potential for rupture, complex surgery, death. Improved morphology following TEVAR documented, but evidence improved overall survival lacking. The costs impact quality life also needed. Methods trial a randomized, open-label, superiority...
Objective: The multibranched off-the-shelf Zenith® t-Branch (Cook Medical, Bloomington, IN) device is commonly chosen for endovascular repair of thoracoabdominal aortic aneurysms. aim this study was to report early and mid-term outcomes in all patients treated with the Norway; Design Methods: A retrospective multicenter Norwegian centers performing complex undertaken. T-Branch from 2014 2020 were included. All postoperative computed tomography angiography images reviewed, demographic,...
Abstract Circulating compounds such as drugs and nutritional components might adhere to the oxygenator fibers tubing during ECMO support. This study evaluated amount of supplements adsorbed circuit under controlled ex vivo conditions. Six identical circuits were primed with fresh human whole blood maintained physiological conditions at 36 °C for 24 h. A dose supplement calculated a 70 kg patient was added. 150 mL volume drawn from priming bag control samples kept similar Blood obtained...
Unstable atherosclerotic carotid plaques with intraplaque neovascularization (IPN) carry a substantial risk for ischemic stroke. Conventional ultrasound methods fall short in detecting IPN, where superb microvascular imaging (SMI) has emerged as promising tool both visualizing and quantification. High levels of fibroblast growth factor 23 (FGF-23) have, observational studies, been suggested related to cardiovascular morbidity mortality. The association FGF-23 plaque instability remains...
Larsen syndrome is a hereditary disorder characterized by osteochondrodysplasia, congenital large-joint dislocations, and craniofacial abnormalities. The autosomal dominant type caused mutations in the gene that encodes connective tissue protein, filamin B (FLNB). Loeys-Dietz (LDS) an arterial aneurysms, dissections tortuosity, skeletal, including craniofacial, manifestations. Mutations five genes involved transforming growth factor beta (TGF-β) signaling pathway cause types of LDS. Stickler...
Atresia of the infrarenal inferior vena cava (IVC) is associated with thrombophilia and antithrombin (AT) deficiency (ATD) due to homozygosity for so-called Budapest 3 variant, c.391C > T, in gene, SERPINC1.
Abstract Background : Contemporary management of uncomplicated type B aortic dissections (uTBAD) is based on the acuity and various morphological features. Medical therapy mandatory, while risks early thoracic endovascular repair (TEVAR) are balanced against potential for rupture, complex surgery, death. Improved morphology following TEVAR documented, but evidence improved overall survival lacking. The costs impact quality-of-life also needed. Methods trial a randomized, open label,...
Abstract Background Mitral valve prolapse is a common finding in patients with Marfan and Loyes-Dietz syndrome. annulus disjunction (MAD), an atrial displacement of the hinge point mitral valve, has previously been associated non-syndromic MVP life-threatening ventricular arrhythmias. Purpose We aimed to assess prevalence MAD syndrome relate presence prolapse. Methods included genotype positive syndrome, fulfilling Revised Ghent Criteria. was defined as superior leaflets' ≥2mm beyond...
Abstract Funding Acknowledgements Type of funding sources: Public Institution(s). Main source(s): South-Eastern Norway Regional Health Authority Background Mitral valve prolapse is a common finding in patients with Marfan (MFS) and Loeys-Dietz syndromes (LDS). annulus disjunction (MAD) an atrial displacement the hinge point mitral that frequently coexists prolapse, but its clinical relevance connective tissue disorders unknown. Purpose To explore association between MAD severity aortic...