A5049490876- Cutaneous lymphoproliferative disorders research
- Dermatology and Skin Diseases
- Nail Diseases and Treatments
- Autoimmune Bullous Skin Diseases
- Cutaneous Melanoma Detection and Management
- Hair Growth and Disorders
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Genetic and rare skin diseases.
- Psoriasis: Treatment and Pathogenesis
- Cancer and Skin Lesions
- Reconstructive Facial Surgery Techniques
- Lymphoma Diagnosis and Treatment
- Inflammasome and immune disorders
- Oral Health Pathology and Treatment
- Digital Imaging in Medicine
- Polyomavirus and related diseases
- Medical Malpractice and Liability Issues
- Body Image and Dysmorphia Studies
- Oral and Maxillofacial Pathology
- Urticaria and Related Conditions
- Atherosclerosis and Cardiovascular Diseases
- Ear Surgery and Otitis Media
- Nonmelanoma Skin Cancer Studies
- Full-Duplex Wireless Communications
Hospital Universitario Reina Sofía
2018-2025
Instituto Maimónides de Investigación Biomédica de Córdoba
2019-2025
University of Córdoba
2019-2025
Icahn School of Medicine at Mount Sinai
2023-2024
Mount Sinai Medical Center
2023
Abstract Background The incidence of adult‐onset atopic dermatitis (AOAD) is increasing. However, the unique characteristics AOAD compared to pediatric‐onset AD persisting into adulthood (POAD) are underexplored, hampering development targeted‐therapeutics for this growing population. We thus assessed profile in skin and blood that POAD. Methods collected biopsies from adults with AOAD, POAD, healthy controls ( n = 15 each group). Skin samples were analyzed by RNA sequencing, qRT‐PCR,...
This scoping review explores the effectiveness of IL-1 pathway inhibitors in managing PSTPIP1-associated inflammatory diseases (PAID). These are marked by abnormal activation due to genetic mutations.
Abstract Background This is the first report on effects of abrocitinib, a Janus kinase 1–selective inhibitor, expression skin biomarkers in patients with moderate‐to‐severe atopic dermatitis (AD). Methods JADE MOA (NCT03915496) was double‐blind Phase 2a trial. Adults were randomly assigned 1:1:1 to receive monotherapy once‐daily abrocitinib 200 mg, 100 or placebo for 12 weeks. The primary endpoint change from baseline markers inflammation (matrix metalloproteinase [MMP]‐12), epidermal...
Abstract Introduction Non-segmental vitiligo (NSV) is an autoimmune condition characterized by melanocyte loss. While skin-specific mechanisms are well-studied, systemic immune dysregulation contributing to NSV pathogenesis remains unclear. Objective This study employs a multi-omic single-cell approach investigate circulating cells in NSV, integrating transcriptional and chromatin accessibility data. Methods An integrative scRNA-seq/scATAC-seq analysis was conducted on PBMCs from patients...
Abstract Introduction Tape‐strips, a minimally invasive method validated for the evaluation of several skin diseases, may help identify asthma‐specific biomarkers in children with allergic asthma. Methods Skin tape‐strips were obtained and analyzed RNA‐Seq from moderate asthma (MAA) ( n = 11, mean age 7.00; SD 1.67), severe (SAA) 9, 9.11; 2.37), healthy controls (HCs) 12, 7.36; 2.03). Differentially expressed genes (DEGs) identified by fold change ≥2 false discovery rate <0.05....
Alopecia areata (AA) is an autoimmune disease causing non-scarring hair loss, with both genetic and environmental factors implicated. Recent research highlights a possible role for scalp microbiota in influencing local systemic inflammatory responses, potentially impacting AA progression. This study examines the link among imbalances, severity, inflammation. We conducted cross-sectional 24 participants, including patients of varying severities healthy controls. Scalp microbial communities...
A 42-year-old man with a history of psoriasis vulgaris was referred to our dermatology department 6 weeks worsening psoriasis. He had started treatment for bipolar disorder valproic acid 4 months prior. The patient crusty, adherent plaques reddish, sharply demarcated borders
This research-on-research study describes efforts to develop non-Cochrane systematic reviews (SRs) by analyzing demographical and time-course collaborations between international institutions using protocols registered in the International Prospective Register of Systematic Reviews (PROSPERO) or published scientific journals. We have an a priori protocol this study. Protocols journals were searched MEDLINE Embase databases; query terms "Systematic review" [Title] AND "protocol" from February...
Teledermatology is now fully incorporated into our clinical practice. However, after reviewing current legislation on the ethical aspects of teledermatology (data confidentiality, quality care, patient autonomy, and privacy) as well insurance professional responsibility, we observed that a specific regulatory framework still lacking related legal are at preliminary stage development. Safeguarding confidentiality autonomy ensuring secure storage transfer data essential telemedicine. One main...
Chin reconstruction poses a significant task for dermatologic surgeons due to its unique contour and shape, as well the fact that it features thickest skin on face, resulting in typically poorer scarring this area compared other facial locations.1 There are numerous reconstructive options employed closure of oncological surgical defects chin region, ranging from advancement, transposition2 or rotation flaps much more complex choices like free flaps.3 We present case defect midportion...
Die Rekonstruktion des Kinns ist wegen der besonderen Kontur und Form weil es sich um die dickste Haut im Gesicht mit meistens schlechterer Narbenbildung Vergleich zu anderen Gesichtsbereichen für Dermatochirurgen herausfordernd.1 Für den Verschluss onkologischer chirurgischer Defekte am Kinn gibt zahlreiche Rekonstruktionsmöglichkeiten, von Verschiebe-, Transpositions-2 oder Rotationslappen bis hin weitaus komplexeren Optionen wie freien Lappen reichen.3 Wir stellen einen Fall eines...