A5036208747- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Biology and Fertility
- Ectopic Pregnancy Diagnosis and Management
- Ovarian function and disorders
- Prenatal Screening and Diagnostics
- Reproductive System and Pregnancy
- Pregnancy and Medication Impact
- Endometriosis Research and Treatment
- Biochemical Analysis and Sensing Techniques
- Pelvic floor disorders treatments
- Adolescent and Pediatric Healthcare
- Obesity, Physical Activity, Diet
- Sirtuins and Resveratrol in Medicine
- Regulation of Appetite and Obesity
- Pregnancy and preeclampsia studies
- Diet, Metabolism, and Disease
- COVID-19 Impact on Reproduction
- Epigenetics and DNA Methylation
- Histone Deacetylase Inhibitors Research
- Ferroptosis and cancer prognosis
- Adenosine and Purinergic Signaling
- Nutrition, Genetics, and Disease
- Antioxidant Activity and Oxidative Stress
- Maternal and fetal healthcare
Guangxi Medical University
2023-2025
First Affiliated Hospital of GuangXi Medical University
2023-2025
National Clinical Research
2024
Peking University
2024
Peking University Third Hospital
2024
Ministry of Education of the People's Republic of China
2024
Beijing Obstetrics and Gynecology Hospital
2024
Tumor Hospital of Guangxi Medical University
2023
Abstract Background: The sirtuin family is well recognized for its crucial involvement in various cellular processes. Nevertheless, studies on role the human endometrium are limited. This study aimed to explore expression and localization of endometrium, focusing 3 (SIRT3) potential oxidative imbalance polycystic ovary syndrome (PCOS). Methods: Endometrial specimens were collected from both patients with PCOS controls undergoing hysteroscopy at Center Reproductive Medicine, Peking University...
Background: The relationship between the intake of artificial sweetener (AS) and adverse pregnancy outcomes is under-researched, existing studies yield inconsistent conclusions. Methods/Objectives: A mendelian randomization (MR) approach was employed to investigate causal AS outcomes. Instrumental variables related exposure phenotype were selected for analysis. analysis conducted using genome-wide association summary data from public datasets. Inverse variance weighted, MR-Egger, weighted...
Abstract Recurrent implantation failure (RIF) is a leading impediment to assisted reproductive technology, yet the underlying pathogenesis of RIF remains elusive. Recent studies have sought uncover novel biomarkers and etiological factors by profiling transcriptomes endometrial samples. Nonetheless, inherent heterogeneity among published scarcity experimental validations hinder identification robust markers RIF. Hence, we integrated six publicly accessible datasets with 209 samples,...
Abstract Purpose To investigate the association between IR and pregnancy outcomes in URIF patients, as well to evaluate potential benefits of metformin improving this population. Methods A total 250 women diagnosed with URIF, undergoing vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) from January 2019 February 2022, were recruited study. The patients divided into group non-IR according homeostasis model assessment (HOMA) index. further classified based on whether they...
The relationship between the intake of artificial sweetener (AS) and adverse pregnancy outcomes is under-researched, existing studies yield inconsistent conclusions. A Mendelian randomization (MR) approach was employed to investigate causal AS outcomes. Instrumental variables related exposure phenotype were selected for analysis. analysis conducted using genome-wide association study summary data from public datasets. inverse variance weighted, MR-Egger, weighted median, simple mode, mode...
<title>Abstract</title> <bold>Background: </bold>Cervical cancer (CC) is the second most prevalent mortality rate for women’ globally and fourth gynecological tumor. Dysregulation of histone acetylation (HA) influences pathogenesis cancer. However, there a dearth comprehensive research on HA in CC. <bold>Methods: </bold>We conducted univariate multivariate Cox LASSO regression analyses to assess prognostic relevance 36 HA-related genes identified previous studies. A model was developed by...
To assess the safety and efficiency of in vitro fertilization/ intracytoplasmic sperm injection embryo transfer (IVF/ICSI-ET) on maternal neonatal perinatal outcomes women (≥40y) with singleton pregnancies.
Both in vitro fertilization and embryo transfer (IVF-ET) intracytoplasmic sperm injection (ICSI-ET) have been recommended for unexplained primary infertility after recurrent artificial insemination with homologous semen failure (UAIHF), but few studies focused on the safety efficiency of IVF/ICSI-ET technique these patients. In this study, we compared outcomes perinatal postnatal complications between UAIHF patients tubal (TI) patients.We conducted a retrospective study TI who underwent at...
The female ovaries are critical for follicle growth and development in the process known as “folliculogenesis”. This complex is regulated by various factors, among which microenvironment around follicles appears to be crucial. According previous studies, folliculogenesis an energy-demanding process. In fact, well-balanced follicular energy metabolism associated with ovarian function fertility. Consequently, glucose has been widely described main source of during folliculogenesis. Generally,...
BackgroundWe previously reported that obese mice had significantly high lipid content in embryos, and excessive lipids are detrimental to embryonic development. However, whether maternal obesity has an effect on vitrification injury subsequent pregnancy outcomes is still controversial. This study was conducted clarify the influence of by vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI).MethodsWe retrospectively collected medical record IVF/ICSI patients from reproductive...
Objective: Some patients fail to obtain an embryo for transplantation during previous in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles, and require multiple reproductive treatments. This study aimed evaluate whether changing the control ovarian stimulation (COS) protocol subsequent cycle could improve laboratory clinical outcomes these patients. Methods: Patients without a transplantable (TE) IVF/ICSI cycles were recruited their second cycles. They classified...