A5100338380- Intensive Care Unit Cognitive Disorders
- Anesthesia and Neurotoxicity Research
- Central Venous Catheters and Hemodialysis
- Neurological Disease Mechanisms and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Genomics and Phylogenetic Studies
- Vascular Procedures and Complications
- Parkinson's Disease and Spinal Disorders
- Myasthenia Gravis and Thymoma
- Anesthesia and Sedative Agents
- Advanced Neuroimaging Techniques and Applications
- Neurological Disorders and Treatments
- Family and Patient Care in Intensive Care Units
- Acute Ischemic Stroke Management
- Cancer Genomics and Diagnostics
- Organ Transplantation Techniques and Outcomes
- Atmospheric and Environmental Gas Dynamics
- Electrocatalysts for Energy Conversion
- Liver physiology and pathology
- Hydrogen Storage and Materials
- Ectopic Pregnancy Diagnosis and Management
- Autoimmune Neurological Disorders and Treatments
- Cancer Treatment and Pharmacology
- Botulinum Toxin and Related Neurological Disorders
- Pregnancy and Medication Impact
Tianjin University of Science and Technology
2024
Liuzhou Maternal and Child Health Hospital
2024
Beijing Tsinghua Chang Gung Hospital
2024
Tsinghua University
2024
Changchun Normal University
2024
Southwest University of Science and Technology
2024
Sun Yat-sen University
2011-2023
Fudan University
2019-2023
The First Affiliated Hospital, Sun Yat-sen University
2009-2023
Zhongshan Hospital
2019-2023
Purpose: This study aimed to identify brain areas with white matter changes that contribute motor recovery of affected limbs during acute sub-acute phases subcortical infarction. Methods: Diffusion tensor imaging was performed 1, 4, and 12 weeks after stroke onset in 18 patients acu te infarct, age- risk factor-matched controls. Fugl-Meyer scale used assess levels impairment, Statistical Parametric Mapping applied determine fractional anisotropy (FA) for the entire order correlated recovery....
Background: Structural variations (SVs) are common genetic alterations in the human genome that could cause different phenotypes and diseases, including cancer. However, detection of structural using second-generation sequencing was limited by its short read length, which restrained our understanding variations. Methods: In this study, we developed a 28-gene panel for long-read employed it to Oxford Nanopore Technologies Pacific Biosciences platforms. We analyzed 28 breast cancer-related...
Abstract Current methods for evaluating the accuracy of germline variant calls are restricted to easy-to-detect high-confidence regions, thus ignoring a substantial portion difficult variants beyond benchmark regions. We established four DNA reference materials from immortalized cell lines derived Chinese Quartet including parents and monozygotic twins. integrated 4.2 million small 15,000 structural multiple platforms bioinformatic pipelines reliability inside The genetic built-in-truth...
Abstract Background Patients treated in the intensive care unit (ICU) may experience a reversal of day and night. The circadian rhythm ICU patients can be disturbed. Methods To explore relationship between delirium rhythms melatonin, cortisol sleep. A prospective cohort study was carried out surgical tertiary teaching hospital. who were conscious during stay after surgery scheduled to for more than 24 h enrolled. Serum melatonin plasma levels measured three times by drawing arterial blood on...
1. Whether damage to the blood-brain barrier (BBB) occurs in remote areas after a focal cortical lesion remains unknown. The present study investigated tight junction-related proteins and junction microstructure ipsilateral thalamus during acute stage middle cerebral artery occlusion (MCAO) aspiration (CAL) rats. 2. Thirty-six hypertensive normotensive rats were subjected MCAO or CAL; another 18 each group submitted sham operation. Zonula Occluden (ZO)-1, occludin albumin detected by western...
Hybrid heterostructure materials have received considerable attention due to the integration of each component and abundant functional applications in micromotor, catalyst, photothermal therapy, drug delivery, bioimaging. However, preparation...
Executive dysfunction has been observed in patients with left-sided anterior corona radiata infarction. However, whether posterior infarction could cause executive is unclear. Also, secondary damage the left frontal white matter following ipsilateral infarct causal or not and contributes to occurrence development of dysfunction, still uncertain.Twelve underwent diffusion tensor imaging (DTI) an functional assessment at week 1 (W1), 4 (W4), 12 (W12) after onset. Color duplex sonography...
Postoperative delirium is a common severe complication in patients the intensive care unit after cardiac surgery. We developed two-stage prediction model and quantified risk of developing postoperative to assist early prevention before surgery.We conducted prospective cohort study consecutively recruited adult The Confusion Assessment Method for was used diagnose 5 days postoperatively. stage I constructed using patient demographics, health conditions laboratory results obtained...
Objective Nonconvulsive status epilepticus (NCSE) is an uncommon clinical manifestation in patients with TBC1D24 mutations. In addition, NCSE has not been reported as a syndrome together cerebellar ataxia and ophthalmoplegia. Methods Here, we report the genetical features of 4-year-old patient NCSE, ophthalmoplegia caused by novel We performed 24hour-video electroencephalogram (EEG) result, MR imaging gene sequencing for her parents to diagnosis. Results this patient, identified...
In this review, we summarized three cases of myasthenia gravis (MG) with taste disorder and describe their clinical features in detail. Three MG patients presented significant bulbar palsy symptoms, high AChR-Ab titers, negative MuSK-Ab, were diagnosed thymoma. Furthermore, observed that dysgeusia could manifest earlier than the occurrence typical even predict a relapse or myasthenic crisis course MG. We believe is non-motor symptom MG, which especially exists thymoma serious palsy....
Abstract Aim The aims of this study are: (a) to determine the incidence postoperative delirium (POD) among surgical intensive care unit (ICU) patients in China and identify risk factors, especially, which are modifiable have value for developing a prediction model; (b) develop validate model recognize high‐risk ICUs; (c) investigate short‐ long‐term outcomes delirious predictors patient outcomes. Design A single‐centre prospective cohort study. Methods Patients will be enrolled from three...
Introduction: Heart valvular calcification (HVC) is an important predictor of cardiovascular events (CEs) and all-cause mortality in dialysis patients. Patients the early stage or those with central venous catheters (CVC) are also at high risk mortality. It could be a confounding factor for prognosis HVC on CE. Methods: From March 2017 to April 2022, CE was studied retrospectively 158 hemodialysis (HD) patients who used arteriovenous fistulas grafts as vascular access entered HD more than 12...
A 57-year-old woman with myasthenia gravis (MG), who had experienced a myasthenic crisis, complained of coughing while drinking. At first, this appeared to be sequela the crisis. However, after further investigation, problem was identified as tracheoesophageal fistula, complication tracheostomy. Here, we describe special case in hope that can improve diagnostic accuracy by providing reminder for other physicians consider differences between MG and fistula. It is very important pay more...
<b><i>Background:</i></b> Orthostatic hypotension (OH) is the key manifestation of autonomic dysfunction with many causes. Systemic neurological causes such as paraneoplastic syndrome are usually ignored. <b><i>Methods:</i></b> We retrospectively analyzed clinical and examination data 2 patients who were hospitalized, onset symptom OH diagnosed syndrome. <b><i>Results:</i></b> The characteristic an initial OH, positive...
Abstract Aims To evaluate the feasibility and efficacy of Mirabilite combined with Lactulose in older patients after abdominal surgery. Design It is a retrospective observational cohort study pre post intervention group. Methods Medical records were retrospectively reviewed postoperative Intensive Care gastrointestinal tract dysfunction (aged >60 years) Surgical Unit from January 2017–December 2018. Results One hundred sixty‐seven post‐surgical analysed; 74 received + treatment 93...
Silent brain infarction (SBI) had a higher prevalence in ischemic stroke patients than healthy population. Intracranial artery calcification, as the important component of atherosclerosis, is known risk factor stroke. Whether it also SBI uncertain. We aimed to assess association between and carotid siphon calcification (CSC) patients. retrospectively collected consecutive data acute with without by Magnetic Resonance Imaging (MRI) using non-contrast Computerized Tomography (NCCT). used...
Abstract Aims To investigate the beliefs and attitudes of intensive care unit (ICU) nurses patients' family members towards an open visitation policy in ICU China to explore reasons that promote or hinder improve policy. Background Open policies are widely recommended many countries. However, there gaps between evidence practice. Most ICUs still use a restrictive for visits, which raises controversy. There limited visiting times, visitors not allowed enter ICU. Study Design A multicentre...