Jinmei Chen

ORCID: 0000-0003-0981-760X
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Research Areas
  • Advanced Radiotherapy Techniques
  • Lung Cancer Diagnosis and Treatment
  • Effects of Radiation Exposure
  • Brain Metastases and Treatment
  • Lung Cancer Research Studies
  • Traditional Chinese Medicine Studies
  • Ginseng Biological Effects and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Head and Neck Cancer Studies
  • Cancer Cells and Metastasis
  • Cancer survivorship and care
  • Blood transfusion and management
  • Constructed Wetlands for Wastewater Treatment
  • Management of metastatic bone disease
  • Soil Carbon and Nitrogen Dynamics
  • Pharmacological Effects of Natural Compounds
  • Medical Research and Treatments
  • Genomics, phytochemicals, and oxidative stress
  • Seed Germination and Physiology
  • Electrochemical sensors and biosensors
  • Folate and B Vitamins Research
  • Signaling Pathways in Disease
  • Nematode management and characterization studies
  • Ultrasound and Hyperthermia Applications
  • Sports and Physical Education Research

Northwest A&F University
2024

CNEX (China)
2024

First Affiliated Hospital of Fujian Medical University
2009-2024

Fujian Medical University
2009-2024

Northwest University
2024

First People's Hospital of Nanning
2023

Shanghai Sixth People's Hospital
2022

Shanghai Jiao Tong University
2022

Hebei Normal University
2022

Guangxi University of Chinese Medicine
2020

Radiation-induced lung injury (RILI) is a common complication of thoracic radiotherapy, but efficacious therapy for RILI lacking. This study ascertained whether glycyrrhetinic acid (GA; functional hydrolyzed product glycyrrhizic acid, which extracted from herb licorice) can protect against and investigated its relationship to the transforming growth factor (TGF)-β1/Smads signaling pathway. C57BL/6 mice were divided into four groups: control group, GA group two irradiation (IR) groups. IR...

10.1093/jrr/rrw091 article EN cc-by-nc Journal of Radiation Research 2016-09-27

Hepatocellular carcinoma (HCC) is a malignant cancer with rapid progression, vascular invasion, high recurrence rate and poor prognosis, so it necessary to take early measures halt this process. Accumulating evidence indicates that collagen XV (translated by Col15a1) basement membrane molecule related tumour metastasis in several organs. However, the potential function of liver associated HCC remains be further elucidated.Col15a1 was overexpressed HepG2 HCCLM3 cells. CCK8 colony formation...

10.21037/jgo-22-299 article EN Journal of Gastrointestinal Oncology 2022-09-02

Spinal infection is a rarely occurred pathology, whose diagnosis remains major challenge due to the low sensitivity of culturing techniques. Metagenomic next-generation sequencing (mNGS) novel approach identify pathogenic organisms in infectious diseases. In this study, mNGS technology was adopted for detection spinal from tissue and pus samples. Additionally, diagnostic performance evaluated, by comparing it with that conventional microbial culture, histopathological results as gold...

10.3389/fcimb.2022.967584 article EN cc-by Frontiers in Cellular and Infection Microbiology 2022-10-27

The aim of this study was to investigate the association between absolute volumes lung spared from low-dose irradiation and radiation-induced injury (RILI) after intensity-modulated radiotherapy (IMRT) for cancer. normal relative receiving greater than 5, 10, 20 30 Gy (V5–30) mean dose (MLD), (AVS5–30) bilateral ipsilateral lungs 83 patients were recorded. Any clinical factors dose–volume parameters with Grade ≥2 RILI analyzed. median follow-up 12.3 months; 18 (21.7%) cases 2 RILI, seven...

10.1093/jrr/rrv057 article EN cc-by-nc Journal of Radiation Research 2015-10-09

Abstract The addition of La 2 O 3 to an aniline polymerizing system promote the formation polyaniline nanofibers (PANI-La ) is herein demonstrated. fiberization rate significantly increased by inducing . Only trace amounts lanthanum advantageously remain in product, which therefore negligibly influence electrochemical characteristics resulting fibers. Research for reaction kinetics PANI-La nanofiber indicates that redox between leucoemeraldine and emeraldine controlled electron transfer...

10.1524/zpch.2013.0252 article EN Zeitschrift für Physikalische Chemie 2013-01-01

The aim of the present study was to investigate role complement activation in pathogenesis neuropathic pain (NPP) induced by peripheral nerve injury. We modified a classical chronic constriction injury (CCI) model (mCCI), and verified its reliability rats. Furthermore, reverse transcription-PCR immunohistochemistry were conducted spinal dorsal horn effect inhibitor, cobra venom factor (CVF), on behavior mCCI found that rats group presented better general condition, without signs autophagy...

10.3892/ijmm.2013.1344 article EN International Journal of Molecular Medicine 2013-04-11

The present study aimed to investigate the effect of protease-activated receptor 2 (PAR-2) on cell proliferation, invasion and metastasis in esophageal EC109 line. Two short hairpin RNA (shRNA) expression plasmids were constructed based PAR-2 mRNA sequence humans, they transfected into cancer line, stable interference line (shRNA-PAR-2 EC109) was obtained by puromycin selection. Following transfection shRNA-1, significantly downregulated level protein cells (P<0.05). proliferation with shRNA...

10.3892/ol.2017.6711 article EN Oncology Letters 2017-08-03

Abstract Background: Patients with brain metastases (BM) often suffer from peritumoral edema. The purpose of study was to assess the effect anlotinib in alleviating edema and increasing tumour regression symptomatic BM patients during radiotherapy. Methods: volumes (Vt), (Ve) whole (Vb) were delineated based on MRI acquired before after rates Vt, Ve lesion volume (Vl =Vt + Ve) percentage Vl Vb assessed 1 month radiotherapy compared pre-radiotherapy. A multivariate logistic analysis used...

10.21203/rs.3.rs-4192392/v1 preprint EN cc-by Research Square (Research Square) 2024-04-05

The aim of the present study was to assess clinical outcomes and prognostic factors lung adenocarcinoma patients with brain metastases (BMs) after intracranial local therapy.

10.2147/cmar.s476837 article EN cc-by-nc Cancer Management and Research 2024-07-01

The aim of the present study was to investigate safety and short‑term results early high volume lung lavage in treatment acute severe smoke inhalation injuries dogs. A high‑volume normal saline complex solution left performed 1 h subsequent bilateral pulmonary sawdust injury Lavage right conducted following an interval 30 min or 4 h. perfluorodecalin dogs with unilateral injury. identified that between two lungs safer compared a 30‑min interval. Following lavage, increase levels free radical...

10.3892/mmr.2013.1877 article EN Molecular Medicine Reports 2013-12-23

To explore the effect of tumor and normal lung volumes on volume-dose parameters in patients with non-small-cell cancer (NSCLC) who had undergone intensity-modulated radiation therapy (IMRT).The clinical data 208 NSCLC underwent radical IMRT between June 2014 2018 were retrospectively analyzed. A regression model curve was used to evaluate relative receiving greater than 5 20 Gy (V5, V20), mean dose (MLD), absolute spared from (AVS5, AVS20).The V5, V20, MLD bilateral fitted a quadratic...

10.6061/clinics/2021/e2769 article EN cc-by Clinics 2021-01-01

To explore the effectof tumor volume on pulmonary dose-volume parameters by intensity-modulated radiation therapy (IMRT) in non-small cell lung cancer (NSCLC), and to provide a basis for dose IMRT treatment. Methods: A total of 204 patients with NSCLC received were retrospectively analyzed from June, 2009 October, 2013. The prescribed planning target (PTV) primary was 60-66Gy (2.00-2.25 Gy, 27-33 times all). fractional percent >5 or 20 Gy (V5, V20), absolute <5 (AVS5).The mean (MLD) normal...

10.11817/j.issn.1672-7347.2017.04.008 article EN PubMed 2017-04-28

Objective To evaluate the effect of tumor shape and location on pulmonary dose-volume parameters by intensity-modulated radiation therapy (IMRT) in patients with non-small cell lung cancer (NSCLC), aiming to provide a reference basis for establishing limits during IMRT. Methods Clinical data 208 NSCLC undergoing radical IMRT from June 2009 2016 were retrospectively analyzed. According location, cases divided into vertical bar group (n=127) horizontal (n=81), superior (n=103) inferior...

10.3760/cma.j.issn.1004-4221.2018.08.012 article EN 2018-08-15
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