- Lung Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Cancer, Hypoxia, and Metabolism
- Traditional Chinese Medicine Analysis
- Effects of Radiation Exposure
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Cancer Studies
- Click Chemistry and Applications
- Medicinal Plant Pharmacodynamics Research
- Intestinal Malrotation and Obstruction Disorders
- HIV/AIDS drug development and treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Traditional Chinese Medicine Studies
- HIV Research and Treatment
- Ferroptosis and cancer prognosis
- Ultrasound and Hyperthermia Applications
- Calcium signaling and nucleotide metabolism
- MRI in cancer diagnosis
- Herbal Medicine Research Studies
- Photodynamic Therapy Research Studies
- Lipid metabolism and disorders
- Ginkgo biloba and Cashew Applications
- Immune cells in cancer
- Hearing, Cochlea, Tinnitus, Genetics
- Neuroendocrine Tumor Research Advances
Shanghai Municipal Center For Disease Control Prevention
2024
First People's Hospital of Foshan
2024
China-Japan Friendship Hospital
2024
Fujian Medical University
2013-2023
First Affiliated Hospital of Fujian Medical University
2013-2023
Zhejiang University
2022
Sun Yat-sen Memorial Hospital
2021
Sichuan University
2019-2021
West China Second University Hospital of Sichuan University
2019-2021
Sun Yat-sen University
2017-2021
Icaritin (ICT) is a hydrolytic form of icariin isolated from plants the genus Epimedium. This study was to investigate radiosensitization effect icaritin and its possible underlying mechanism using murine 4T1 breast cancer cells. The combination at 3 µM or 6 with 8 Gy ionizing radiation (IR) in clonogenic assay yielded an ER (enhancement ratio) 1.18 1.28, CI (combination index) 0.38 0.19 DRI (dose reducing 2.51 5.07, respectively. These strongly suggest that exerted synergistic killing (?)...
BACKGROUND:Gastric cancer (GC) is a worldwide malignancy and the molecular mechanism of GC carcinogenesis has not been fully elucidated. Our previous study suggested CDCA5 played role in development via regulating cell proliferation, migration, apoptosis cells. MATERIAL AND METHODS:Here, we first carried out bioinformatics analysis found cyclin-dependent kinase 1 (CDK1) was possibly associated with using STRING. Then, expression levels CDK1 tissues were estimated through Oncomine The Cancer...
This study aims to explore the applicability of Nutrition Risk Screening 2002 (NRS2002) tool in screening nutritional risk and Patient-Generated Subjective Global Assessment (PG-SGA) determining nutrition status nasopharyngeal carcinoma (NPC) patients.NRS2002 PG-SGA were simultaneously applied evaluate NPC patients before induction chemotherapy, as well after radiotherapy. The results considered golden standard evaluating status, ROC curve value Youden index analyze NRS2002 effectiveness...
Naoxintong Capsule (NXT), a renowned traditional Chinese medicine (TCM) formulation, has been broadly applied in China for more than 30 years. Over decades, accumulating evidences have proven satisfactory efficacy and safety of NXT treating cardiovascular cerebrovascular diseases (CCVD). Studies conducted unceasingly, while this growing latest knowledge not yet interpreted properly summarized comprehensively. Hence, we systematically review the advancements research, from its chemical...
Compound Xueshuantong Capsule (CXC) is a traditional Chinese herbal formula composed of root Panax pseudoginseng var. notoginseng (Burkill) G. Hoo & C.L. Tseng, Astragalus membranaceus mongholicus (Bunge) P.K. Hsiao, Salvia miltiorrhiza charbonnelii (H. Lév.) C.Y. Wu, and Scrophularia ningpoensis Hemsl. CXC was approved by the China Food Drug Administration in 2003 (No. Z20030017) based on positive clinical effect treatment cardiovascular diseases. The present study designed to elucidate...
Constipation is one of the most common diseases in children and it also a significant healthcare burden, more than many other childhood diseases. For some children, 1st-line treatment cannot relieve their constipation symptoms maybe continue to adolescence. So, alternative options such as lactobacilli are needed. However, effectiveness safety still unclear. To investigate this question, we conduct systematic review meta-analysis.The protocol followed Preferred Reporting Items for Systematic...
To investigate the prognostic value of serum transferrin (TRF) level before intensity-modulated radiation therapy (IMRT) on radio-sensitivity and overall survival (OS) in patients with nasopharyngeal carcinoma (NPC). From October 2012 to 2016, a total 348 NPC First Affiliated Hospital Fujian Medical University were retrospectively analyzed our study. The concentration TRF was detected by method enzyme-linked immunosorbent assay (ELISA). In whole group, 46 received IMRT, 302 IMRT plus...
Discovery and identification of three bioactive compounds affecting endothelial function in Ginkgo biloba Extract (GBE) based on chromatogram-bioactivity correlation analysis. Three portions were separated from GBE via D101 macroporous resin then re-combined to prepare nine samples. 21 samples identified through UFLC-DAD-Q-TOF-MS/MS. Correlation analysis between differences endothelin-1 (ET-1) vivo was conducted. The results indicated that had close relevance ET-1:...
To address the safety problems posed by transportation of boar semen using LN, this study was conducted on short-term storage frozen in dry ice (−79 °C). Boar LN transferred to ice, kept for 1 day, 3 days, 5 7 or 8 and then moved back LN. The quality stored determined evaluate feasibility short-distance with ice. results showed that 60 °C s best condition thawing No significant differences spermatozoa motility, plasma membrane integrity, acrosome integrity were observed after compared (p...
Atopic dermatitis (AD), also called eczema, is one of the most familiar chronic diseases in childhood. A possible pathological mechanism immune dysfunction resulting IgE sensitization to allergens. The recent studies demonstrated that system can be affected by probiotics or prebiotics. However, effectiveness and safety prebiotics on prevention eczema are still unclear. To investigate this question, we conduct a systematic review meta-analysis.The protocol followed Preferred Reporting Items...
Objective To explore the effect of gambogic acid on reversal multi-drug resistance and expressions poly protein 1 (MDR1) P-glycopmtein (P-gp) in SW480/L-OHP cells. Methods Oxaliplatin resistant cells were established by gradually increasing concentration L-OHP intermittent treatment with high-dose parental (SW480). Methyl thiazolyl tetrazollum (MTT) method was used to detect index (RI) acid. The cell cycle, apoptosis determined flow cytometry assay. Expression MDR1 mRNA detected...
The study was conducted to investigate the short-term complications and prognostic factors in patients with esophagogastric junction adenocarcinoma (EGJA).This retrospective included 110 EGJA who underwent surgery from January 2010 November 2012 at First Affiliated Hospital of BengBu Medical College. overall survival were analyzed according patients' clinical characteristics.The incidence postoperative cardiopulmonary significantly higher preoperative disease or elderly (P < 0.05). Four...
The paper aims to discover the development rule of fetal parital bone.One hundred and eighty parietal bones 5-38th weeks old were observed measured.With Noback's method every fetus was made transparent then dyed dark red by Alizarin red.The measured data are added differential integral calculus formula calculate ossification length make correlated regression analysis.The results show that time different parts between 9th 38th week.The sagittal is 85.12 1.07mm coronary 82.62 1.24mm.from...
To explore the effect of tumor and normal lung volumes on volume-dose parameters in patients with non-small-cell cancer (NSCLC) who had undergone intensity-modulated radiation therapy (IMRT).The clinical data 208 NSCLC underwent radical IMRT between June 2014 2018 were retrospectively analyzed. A regression model curve was used to evaluate relative receiving greater than 5 20 Gy (V5, V20), mean dose (MLD), absolute spared from (AVS5, AVS20).The V5, V20, MLD bilateral fitted a quadratic...
To explore the effectof tumor volume on pulmonary dose-volume parameters by intensity-modulated radiation therapy (IMRT) in non-small cell lung cancer (NSCLC), and to provide a basis for dose IMRT treatment. Methods: A total of 204 patients with NSCLC received were retrospectively analyzed from June, 2009 October, 2013. The prescribed planning target (PTV) primary was 60-66Gy (2.00-2.25 Gy, 27-33 times all). fractional percent >5 or 20 Gy (V5, V20), absolute <5 (AVS5).The mean (MLD) normal...
Objective To evaluate the effect of tumor shape and location on pulmonary dose-volume parameters by intensity-modulated radiation therapy (IMRT) in patients with non-small cell lung cancer (NSCLC), aiming to provide a reference basis for establishing limits during IMRT. Methods Clinical data 208 NSCLC undergoing radical IMRT from June 2009 2016 were retrospectively analyzed. According location, cases divided into vertical bar group (n=127) horizontal (n=81), superior (n=103) inferior...
Asthma is the most common chronic lung disease in childhood, leading to a great burden healthcare system worldwide. Despite medication treatment, physiotherapy now applied for asthmatic children aiming improve their function and life quality. However, effectiveness of on quality (QoL) with asthma not clear. We are perform this study provide some evidence doctors treatment.PubMed, Embase Cochrane Library will be searched from inception 31 March 2019 randomized controlled trials (RCTs)...
Inaccurate acupoint determination is one of the problems in moxibustion treatment traditional Chinese medicine. Based on medicine theory and computer stereo vision technology, we developed an intelligent algorithm. Combined with attitude recognition framework, algorithm completes automatic hole finding. Experimental results show that performs well. Rotate mannequin so it at a different angle from camera field view. The difference measurement location all met clinical requirements.