A5100410153- COVID-19 Clinical Research Studies
- Mesenchymal stem cell research
- Long-Term Effects of COVID-19
- Cytokine Signaling Pathways and Interactions
- Coronary Interventions and Diagnostics
- Atherosclerosis and Cardiovascular Diseases
- Lipoproteins and Cardiovascular Health
- Autophagy in Disease and Therapy
- Cancer, Hypoxia, and Metabolism
- Temporomandibular Joint Disorders
- Adipose Tissue and Metabolism
- MicroRNA in disease regulation
- SARS-CoV-2 and COVID-19 Research
- Genetics, Aging, and Longevity in Model Organisms
- Laser Applications in Dentistry and Medicine
- Cancer Immunotherapy and Biomarkers
- Macrophage Migration Inhibitory Factor
- Cancer, Lipids, and Metabolism
- Liver Disease Diagnosis and Treatment
- Acute Myocardial Infarction Research
- Pancreatitis Pathology and Treatment
- Telomeres, Telomerase, and Senescence
- Cancer Treatment and Pharmacology
- Neuroendocrine Tumor Research Advances
- Immune cells in cancer
Second Hospital of Shandong University
2009-2024
Shandong University
2011-2020
Shandong First Medical University
2009
Il-Yang Pharmaceutical (South Korea)
2006
Purpose The objective of this study was to investigate the risk cardiovascular toxicities related PD-1/PD-L1 inhibitors in solid tumors. Methods A literature search performed following participants, interventions, comparisons, outcomes, and design (PICOS) principles, adhered Preferred Reporting Items for Systematic Reviews Meta-Analyses (PRISMA) guidelines. Data analysis conducted using Review Manager version 5.4. Results This meta-analysis included 69 randomized controlled trials (RCTs)...
The coronavirus disease (COVID-19) outbreak has catastrophically threatened public health worldwide and presented great challenges for clinicians. To date, no specific drugs are available against severe acute respiratory syndrome 2. Mesenchymal stem cells (MSCs) appear to be a promising cell therapy owing their potent modulatory effects on reducing healing inflammation-induced lung other tissue injuries. present pilot study aimed explore the therapeutic potential safety of MSCs isolated from...
The outbreak of coronavirus disease (COVID-19) has brought great challenges to the world. objectives this study were describe baseline characteristics and changes biomarkers these COVID-19 patients identify predictive value above markers for patient death. Using death as observational endpoints, clinical data inpatients in a special ward Wuhan, China retrospectively collected. Univariate multivariate Cox regression analyses used evaluate prognostic laboratory changes. This included 75...
Background/Aims: We aimed to evaluate the distribution of abnormal liver-related biomarkers in patients with coronavirus disease (COVID-19) and explore prognostic value elevated liver enzymes synthetic capacity regards patient mortality. Patients Methods: This retrospective observational study included 80 laboratory-confirmed COVID-19 cases. Data were collected from electronic medical record system by a trained team physicians. Alanine aminotransferase (ALT), aspartate (AST), total bilirubin...
Background: The essential hypertension (EH) pathophysiology remains poorly understood. Many studies indicate that reduced leukocyte telomere length (LTL) is involved in the EH pathogenesis, however, direct analysis of arterial (ATL) from patients and normotensive individuals did not show a difference. To address these discrepant observations between LTL ATL, we performed comprehensive analyses LTL, telomerase gene expression their genetic variants healthy controls patients. Methods:...
Mesenchymal stem cells (MSCs) have been shown to be involved in bone injury repair. Programmed cell death 4 (PDCD4) is not only a tumor suppressor gene but also plays roles the regulation of MSC function. The aim study was uncover PDCD4 potential regulatory and mechanisms osteogenic differentiation defect repair MSCs. shRNA technique used knock down expression umbilical cord-derived mesenchymal (shPDCD4-UCMSCs). Their phenotype characterized by flow cytometry verified. We found that...
To evaluate the prognostic value of LP-PLA2 and hs-CRP to stability atherosclerotic plaques. Forty-eight New Zealand White rabbits were randomly divided into control group, stable plaque P53 + drug group. Rabbits in group fed a regular diet. underwent balloon-induced arterial wall injury then diet 1% cholesterol. Then Ad5-CMV transfection 10th week; The pharmacologic triggering with Russell's viper venom (RVV) histamine 24 h 48 before euthanized. Intravascular ultrasound (IVUS) was used...
article: Analysis of clinical efficacy and incidence complications percutaneous coronary intervention in the treatment angina pectoris elderly patients with heart disease - Minerva Surgery 2021 Aug 03 Medica Journals