A5062627255- Plant-Microbe Interactions and Immunity
- Legume Nitrogen Fixing Symbiosis
- Nematode management and characterization studies
- Plant Pathogenic Bacteria Studies
- Soybean genetics and cultivation
- Microbial Community Ecology and Physiology
- Enzyme Catalysis and Immobilization
- Microbial bioremediation and biosurfactants
- Probiotics and Fermented Foods
- Biofuel production and bioconversion
- Plant Pathogens and Fungal Diseases
- Photosynthetic Processes and Mechanisms
- Gut microbiota and health
- Plant Stress Responses and Tolerance
- Nanoplatforms for cancer theranostics
- Cancer-related Molecular Pathways
- Photodynamic Therapy Research Studies
- Protist diversity and phylogeny
- Enzyme Production and Characterization
- Plant Virus Research Studies
- Nigella sativa pharmacological applications
- Plant Parasitism and Resistance
- Essential Oils and Antimicrobial Activity
- Plant Toxicity and Pharmacological Properties
- Cynara cardunculus studies
New York University
2019-2024
New York University Abu Dhabi
2020-2024
The University of Western Australia
2023
University of Technology Sydney
2023
Max Planck Institute for Marine Microbiology
2023
Jahangirnagar University
2019-2020
Southern Illinois University Carbondale
2006-2019
Lahore University of Management Sciences
2015-2018
The Ohio State University
2011-2017
Max Planck Institute of Molecular Plant Physiology
2009
Although the functions of a few effector proteins produced by bacterial and oomycete plant pathogens have been elucidated in recent years, information for vast majority pathogen effectors is still lacking, particularly those plant-pathogenic fungi. Here, we show that avirulence AvrPiz-t from rice blast fungus Magnaporthe oryzae preferentially accumulates specialized structure called biotrophic interfacial complex then translocated into (Oryza sativa) cells. Ectopic expression transgenic...
Abstract Missense mutations in p53 are severely deleterious and occur over 50% of all human cancers. The majority these located the inherently unstable DNA-binding domain (DBD), many which destabilize further expose its aggregation-prone hydrophobic core, prompting self-assembly mutant into inactive cytosolic amyloid-like aggregates. Screening an oligopyridylamide library, previously shown to inhibit amyloid formation associated with Alzheimer’s disease type II diabetes, identified a...
Photodynamic therapy (PDT) and photothermal (PTT) have gained considerable attention as potential alternatives to conventional cancer treatments. However, these approaches remain limited by low solubility, poor stability, inefficient targeting of many common photosensitizers (PSs) agents (PTAs). To overcome the aforementioned limitations, we engineered biocompatible biodegradable tumor-targeted upconversion nanospheres with imaging capabilities. The multifunctional consist a sodium yttrium...
Abstract RPM1-interacting protein 4 (RIN4) is a multifunctional Arabidopsis thaliana that regulates plant immune responses to pathogen-associated molecular patterns (PAMPs) and bacterial type III effector proteins (T3Es). RIN4, which targeted by multiple defense-suppressing T3Es, provides mechanistic link between PAMP-triggered immunity (PTI) effector-triggered suppression of defense. Here we report on structure–function analysis RIN4-mediated PTI. Separable fragments including those...
Abstract Heterodera glycines, the soybean cyst nematode (SCN), causes most damaging chronic disease of (Glycine max). Host resistance requires allele at rhg1. Resistance destroys giant cells created in plant's roots by nematodes about 24 to 48 h after commencement feeding. In addition, 4 8 d later, a systemic acquired develops that discourages later infestations. The molecular mechanisms control rhg1-mediated response appear be multigenic and complex, as judged transcript abundance changes,...
Abstract Background Soybean ( Glycine max (L. Merr.)) resistance to any population of Heterodera glycines (I.), or Fusarium virguliforme (Akoi, O’Donnell, Homma & Lattanzi) required a functional allele at Rhg1/Rfs2 . H. , the soybean cyst nematode (SCN) was an ancient, endemic, pest whereas F. causal agent sudden death syndrome (SDS), recent, regional, pest. This study examined role receptor like kinase (RLK) GmRLK18-1 (gene model Glyma_18_02680 1,071 kbp on chromosome 18 genome...
Abstract Drosophila melanogaster larvae are classified as herbivores and known to feed on non-carnivorous diet under normal conditions. However, when nutritionally challenged these exhibit cannibalistic behaviour by consuming a composed of larger conspecifics. Herein, we report that cannibalism in is confined not only scavenging conspecifics size, but also their eggs. Moreover, such develop normally those grown standard cornmeal medium. When stressed, can consume carnivorous derived from...
Extracts from many types of plants show several evidences beneficial health effects in the living system. Calendula officinalis is a well known medicinal plant our country. The purpose this study was to examine effectiveness C. for control growth and survival microorganisms. inhibition tested by paper disc agar diffusion method. Minimum inhibitory concentration (MIC) determined tube dilution leaf extract showed (MIC, inhibitory) Escherichia coli, Klebsiella pneumoniae, Bacillus subtilis...
Abstract Background The protein encoded by GmRLK18-1 ( Glyma_18_02680 on chromosome 18) was a receptor like kinase (RLK) within the soybean (Glycine max L. Merr.) Rhg1/Rfs2 locus. locus underlies resistance to cyst nematode (SCN) Heterodera glycines (I.) and causal agent of sudden death syndrome (SDS) Fusarium virguliforme (Aoki). Previously leucine rich repeat (LRR) domain expressed in Escherichia coli . Results aims here were evaluate LRRs ability to; homo-dimerize; bind larger proteins;...
Tomato yellow leaf curl virus (TYLCV), a member of the genus Begomovirus Geminiviridae family, causes disease tomato that significantly affects production worldwide. SA (salicylic acid), JA (jasmonic acid) or mimetic, COR (coronatine) applied exogenously resulted in improved resistance against TYLCV infection. When compared to mock treated leaves, pretreatment with three compounds followed by TYCLV stem infiltration also caused greater accumulation H2O2. We employed RNA-Seq (RNA sequencing)...
Abstract Coronatine (COR) is a non‐host specific phytotoxin secreted by Pseudomonas syringae pv. tomato that can induce leaf chlorosis and increase the virulence of pathogens during plant–pathogen interactions. Studies have shown COR regulate multiple physiological processes in plants, but its involvement bacterial pathogenesis plant growth regulation not well understood. In this study, transcriptome sequencing was carried out on 4‐week‐old leaves were either mock‐treated or treated with...
Photosynthetic eukaryotes, such as microalgae and plants, foster fundamentally important relationships with their microbiome based on the reciprocal exchange of chemical currencies. Among these, dicarboxylate metabolite azelaic acid (Aze) appears to play an important, but heterogeneous, role in modulating these microbiomes, it is used a carbon source for some heterotrophs toxic others. However, ability Aze promote or inhibit growth, well its uptake assimilation mechanisms into bacterial...
In most studies of enzyme kinetics it has been found sufficient to use the classical Transition State Theory (TST) Eyring and others. This theory was based on solvent being an ideal dilute substance treated as a heat bath. However, enzymes in organisms adapted very low (psychrophiles) high (thermophiles) temperatures are also subjected variable solute concentrations viscosities. Therefore, TST may not always be applicable reactions carried out various solvents with viscosities ranging from...
Molecular interplay between two species is largely driven by protein–protein interactions and protein modifications that set the pace of co‐evolution in these species. During host–pathogen interactions, proteins involved virulence defence impart tempospatial dynamic post‐translational ( PTM s) to gain advantage for causative Pathogens mainly cause disease plant hosts secreting elicitors (peptides small molecules) or inter‐ intracellular space host cells. These pathogen have evolved a wide...